Age is a risk factor for maladaptive changes in rats exposed to increased pressure loading of the right ventricular myocardium

Cardiology in the Young

Volumn 17, Issue 2, 2007, Pages 202-211

  Vida, Vladimiro L ^a   Angelini, Annalisa ^a   Ausoni, Simonetta ^a   Bilardi, Alessandra ^a   Ori, Carlo ^a   Vlassich, Francesca ^a   Zoso, Valentina ^a   Milanesi, Ornella ^a   Sartore, Saverio ^a   Barbera, Mila della ^a   Zaglia, Tania ^a   Thiene, Gaetano ^a   Stellin, Giovanni ^a  

^a UNIVERSITY OF PADOVA   (Italy)

Author keywords

Congenital defects; Extra cellular matrix; Heart failure; Remodeling; Ventricular function

Indexed keywords

ALPHA ACTIN; MYOSIN HEAVY CHAIN BETA;

AGE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ECHOCARDIOGRAPHY; HEART AFTERLOAD; HEART MUSCLE CAPILLARY; HEART MUSCLE CELL; HEART MUSCLE FIBROSIS; HEART RIGHT VENTRICLE OVERLOAD; HEART VENTRICLE HYPERTROPHY; HEART VENTRICLE REMODELING; HEART VENTRICLE WALL; HEART WEIGHT; MALE; MORPHOMETRICS; NONHUMAN; PROTEIN EXPRESSION; RAT; SPRAGUE DAWLEY RAT;

AGE FACTORS; ANIMALS; BLOTTING, WESTERN; DISEASE MODELS, ANIMAL; ECHOCARDIOGRAPHY; EXERTION; FOLLOW-UP STUDIES; HEART VENTRICLES; HYPERTROPHY, RIGHT VENTRICULAR; MALE; MUSCLE PROTEINS; MYOCARDIAL CONTRACTION; MYOCARDIUM; RATS; RATS, SPRAGUE-DAWLEY; RISK FACTORS; VENTRICULAR FUNCTION, RIGHT; VENTRICULAR PRESSURE;

EID: 34247267593     PISSN: 10479511     EISSN: 14671107     Source Type: Journal    
DOI: 10.1017/S1047951107000376     Document Type: Article

References (21)

1. Wells WJ, Blackstone E. Intermediate outcome after Mustard and Senning procedures: A study by the Congenital Heart Surgeons Society. Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu 2000; 3: 186-197.
2. Duncan BW, Mee RB. Management of the failing systemic right ventricle. Semin Thorac Cardiovasc Surg 2005; 17: 160-169.
3. Brawn WJ. The double switch for atrioventricular discordance. Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu 2005; 8: 51-56.
4. Gorenflo M, Serpi M, Schnabel PA, et al. Pathological changes of the myocardium in patients after atrial repair for transposition of the great arteries: A possible explanation for left ventricular dysfunction after secondary arterial switch. Z Kardiol 2003; 92: 742-746.
5. Rentzsch A, Abd El Rahman MY, Hui W, et al. Assessment of myocardial function of the systemic right ventricle in patients with D-transposition of the great arteries after atrial switch operation by tissue Doppler echocardiography. Z Kardiol 2005; 94: 524-531.
6. Singh TP, Humes RA, Muzik O, Kottamasu S, Karpawich PP, Di Carli MF. Myocardial flow reserve in patients with a systemic right ventricle after atrial switch repair. J Am Coll Cardiol 2001; 37: 2120-2125.
7. Millane T, Bernard EJ, Jaeggi E, et al. Role of ischemia and infarction in late right ventricular dysfunction after atrial repair of transposition of the great arteries. J Am Coll Cardiol 2000; 35: 1661-1668.
8. Schaub MC, Hefti MA, Harder BA, Eppenberger HM. Various hypertrophic stimuli induce distinct phenotypes in cardiomyocytes. J Mol Med 1997; 75: 901-920.
9. Clement S, Chaponnier C, Gabbiani G. A subpopulation of cardiomyocytes expressing alpha-skeletal actin is identified by a specific polyclonal antibody. Circ Res 1999; 85(10): E51-e58.
10. Glantz S. Primer of biostatistics. Fifth ed. McGraw-Hill, United States, 2002.
11. + currents in nonfailing human hearts. Similarities between right septal subendocardial and left subepicardial ventricular myocytes. Circulation 1995; 92: 1179-1187.
12. Urbanek K, Quaini F, Tasca G, et al. Intense myocyte formation from cardiac stem cells in human cardiac hypertrophy. Proc Natl Acad Sci USA 2003; 100: 10440-10445.
13. Li F, Wang X, Capasso JM, Gerdes AM. Rapid transition of cardiac myocytes from hyperplasia to hypertrophy during postnatal development. J Mol Cell Cardiol 1996; 26: 1737-1746.
14. Schmid P, Jaermann T, Boesiger P, et al. Ventricular myocardial architecture as visualised in postmortem swine hearts using magnetic resonance diffusion tensor imaging. Eur J Cardiothorac Surg 2005; 27: 468-472.
15. Anderson RH, Ho SY, Redmann K, Sanchez-Quintana D, Lunkenheimer PP. The anatomical arrangement of the myocardial cells making up the ventricular mass. Eur J Cardiothorac Surg 2005; 28: 517-525.
16. Lunkenheimer PP, Redmann K, Anderson RH. Further discussions concerning the unique myocardial band. Eur J Cardiothorac Surg 2005; 28: 779-780.
17. Manabe I, Shindo T, Nagai R. Gene expression in fibroblasts and fibrosis. Circ Res 2002; 91: 1103-1113.
18. Ikeda S, Hamada M, Hiwada K. Cardiomyocyte apoptosis with enhanced expression of P53 and Bax in right ventricle after pulmonary arterial banding. Life Sci 1999; 65: 925-933.
19. Harada K, Komuro I, Shiojima I, et al. Pressure overload induces cardiac hypertrophy in angiotensin II type 1A receptor knockout mice. Circulation 1998; 97: 1952-1959.
20. Carnes CA, Geisbuhler TP, Reiser PJ. Age-dependent changes in contraction and regional myocardial myosin heavy chain isofrom expression in rats. J Appl Physiol 2004; 97: 446-453.
21. LekanneDeprez RH, van den Hoff MJ, de Boer PA, et al. Changing patterns of gene expression in the pulmonary trunk-banded rat heart. J Mol Cell Cardiol 1998; 30: 1877-1888.