Meliae cortex extract exhibits anti-allergic activity through the inhibition of Syk kinase in mast cells

Toxicology and Applied Pharmacology

Volumn 220, Issue 3, 2007, Pages 227-234

  Lee, Jun Ho ^a   Ko, Na Young ^a   Kim, Nam Wook ^a   Mun, Se Hwan ^a   Kim, Jie Wan ^a   Her, Erk ^a   Kim, Bo Kyung ^a   Seo, Dong Wan ^b   Chang, Hyun Wook ^c   Moon, Tae Chul ^c   Han, Jeung Whan ^d   Kim, Young Mi ^e   Choi, Wahn Soo ^a  

^a Konkuk University School of Medicine   (South Korea)

^b Kangwon National University   (South Korea)

^c Yeungnam University   (South Korea)

^d Sungkyunkwan University   (South Korea)

^e Duksung Women's University   (South Korea)

Author keywords

Allergic reaction; MAP kinase; Mast cells; Meliae cortex; Syk kinase

Indexed keywords

ALCOHOL; COMPOUND 48-80; CYTOKINE; HISTAMINE; MELIAE CORTEX EXTRACT; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PLANT EXTRACT; PROTEIN KINASE B; PROTEIN KINASE SYK; THAPSIGARGIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ALLERGIC REACTION; ANAPHYLAXIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOSE RESPONSE; DRUG ACTIVITY; DRUG MECHANISM; DRUG POTENCY; ENZYME PHOSPHORYLATION; HERB; IC 50; MALE; MAST CELL; MAST CELL DEGRANULATION; MELIAE CORTEX; MOUSE; NONHUMAN;

ANAPHYLAXIS; ANIMALS; ANTI-ALLERGIC AGENTS; CELL DEGRANULATION; CELL LINE, TUMOR; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION; IMMUNOBLOTTING; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MAST CELLS; MELIA AZEDARACH; MICE; MICE, INBRED BALB C; MICE, INBRED ICR; MITOGEN-ACTIVATED PROTEIN KINASES; P-METHOXY-N-METHYLPHENETHYLAMINE; PHOSPHORYLATION; PLANT EXTRACTS; PROTEIN-TYROSINE KINASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; THAPSIGARGIN; TUMOR NECROSIS FACTOR-ALPHA;

MUS;

EID: 34247255349     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2006.10.034     Document Type: Article

References (30)

1. Alfonso A., Cabado A.G., Vieytes M.R., and Botana L.M. Functional compartments in rat mast cells for cAMP and calcium on histamine release. Cell. Signalling 12 (2000) 343-350
2. Ali H., Cunha-Melo J.R., Saul W.F., and Beaven M.A. Activation of phospholipase C via adenosine receptors provides synergistic signals for secretion in antigen-stimulated RBL-2H3 cells. Evidence for a novel adenosine receptor. J. Biol. Chem. 265 (1990) 745-753
3. Beaven M.A. Calcium signalling: sphingosine kinase versus phospholipase C?. Curr. Biol. 6 (1996) 798-801
4. Church M.K., and Levi-Schaffer F. The human mast cell. J. Allergy Clin. Immunol. 99 (1997) 155-160
5. Galli S.J. New concepts about the mast cells. N. Engl. J. Med. 328 (1993) 257-265
6. Gordon J.R., Burd P.R., and Galli S.J. Mast cells as a source of multifunctional cytokines. Immunol. Today 11 (1990) 458-464
7. 2 pathway in a rat mast cell line: indications of different pathways for release of arachidonic acid and secretory granules. J. Immunol. 154 (1995) 5391-5402
8. 2 pathway by FcεR1 is not shared by a G protein-coupled receptor. J. Biol. Chem. 270 (1995) 10960-10967
9. Hirasawa N., Sato Y., Fujita Y., Mue S., and Ohuchi K. Inhibition by dexamethasone of antigen-induced c-Jun N-terminal kinase activation in rat basophilic leukemia cells. J. Immunol. 161 (1998) 4939-4943
10. Ishizuka T., Chayama K., Takeda K., Hamelmann E., Terada N., Keller G.M., Johnson G.L., and Gelfand E.W. Mitogen-activated protein kinase activation through FcεRI and stem cell factor receptor is differentially regulated by phosphatidylinositol 3-kinase and calcineurin in mouse bone marrow-derived mast cells. J. Immunol. 16 (1999) 2087-2094
11. Jabril-Cuenod B., Zhang C., Scharenberg A.M., Paolini R., Numerof R., Beaven M.A., and Kinet J.P. Syk-dependent phosphorylation of Shc: a potential link between FcεR1 and the Ras/MAP kinase signaling pathway through Sos and Grb2. J. Biol. Chem. 271 (1996) 16268-16272
12. Kay A.B. Allergy and allergic diseases. N. Engl. J. Med. 344 (2001) 30-37
13. Kay A.B. Allergy and allergic diseases. N. Engl. J. Med. 344 (2001) 109-113
14. Kemp S.F., and Lockey R.F. Anaphylaxis: a review of causes and mechanisms. J. Allergy Clin. Immunol. 110 (2002) 341-348
15. Kim D.K. Pharmacognosy (2001), Dongmyung-Sa, Seoul 132-133
16. Kim C.D., Lee W., No K., Park S., Lee M., Lim S., and Roh S. Anti-allergic action of buckwheat (Fagopyrum esculentum Moench) grain extract. Int. Immunopharmacol. 3 (2003) 129-136
17. Kovarova M., and Rivera J. A molecular understanding of mast cells activation and the promise of anti-allergic therapeutics. Curr. Med. Chem. 11 (2004) 2083-2091
18. Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage t4. Nature 227 (1970) 680-685
19. Lee J.H., Chang S.H., Park Y.S., Her E., Lee H.Y., Park J.W., Han J.W., Kim Y.M., and Choi W.S. In-vitro and in-vivo anti-allergic actions of Arecae semen. J. Pharm. Pharmacol. 56 (2004) 927-933
20. Lee J.H., Seo J.Y., Ko N.Y., Chang S.H., Her E., Park T., Lee H.Y., Han J.W., Kim Y.M., and Choi W.S. Inhibitory activity of Chrysanthemi sibirici herba extract on RBL-2H3 cells mast cells and compound 48/80-induced anaphylaxis. J. Ethnopharmacol. 95 (2004) 425-430
21. Lee J.H., Kim N.W., Her E., Kim B.K., Hwang K.H., Choi D.K., Lim B.O., Han J.W., Kim Y.M., and Choi W.S. Rubiae Radix suppresses the activation of mast cells through the inhibition of Syk kinase for anti-allergic activity. J. Pharm. Pharmacol. 58 (2006) 503-512
22. Lorentz A., Klopp I., Gebhardt T., Manns M.P., and Bischoff S.C. Role of activator protein 1, nuclear factor-kappaB, and nuclear factor of activated T cells in IgE receptor-mediated cytokine expression in mature human mast cells. J. Allergy Clin. Immunol. 111 (2003) 1062-1068
23. Makino T., Furuta Y., Wakushima H., Fujii H., Saito K., and Kano Y. Anti-allergic effect of Perilla frutescens and its active constituents. Phytother. Res. 17 (2003) 240-243
24. Metcalfe D.D., Kaliner M., and Donlon M.A. The mast cell. Crit. Rev. Immunol. 3 (1981) 23-74
25. Murakami M., Kambe T., Shimbara S., and Kudo I. Functional coupling between various phospholipase A2s and cyclooxygenases in immediate and delayed prostanoid biosynthetic pathways. J. Biol. Chem. 274 (1999) 3103-3115
26. Nagai T., Arai Y., Emori M., Nunome S., Yabe T., Takeda T., and Yamada H. Anti-allergic activity of a Kampo (Japanese herbal) medicine "Sho-seryu-to (Xiao-Qing-Long-Tang)" on airway inflammation in a mouse model. Int. Immunopharmacol. 4 (2004) 1353-1365
27. Putney J.W., and Bird G.S.J. The signal for capacitative calcium entry. Cell 75 (1993) 199-201
28. Siraganian R.P., Zhang J., Suzuki K., and Sada K. Protein tyrosine kinase Syk in mast cell signaling. Mol. Immunol. 38 (2002) 1229-1233
29. Turner H., and Kinet J.-P. Signalling through the high-affinity IgE receptor FcεRI. Nature 402 (1999) B24-B30
30. Zhang C., Baumgartner R.A., Yamada K., and Beaven M.A. Mitogen-activated protein (MAP) kinase regulates production of tumor necrosis factor-alpha and release of arachidonic acid in mast cells. Indications of communication between p38 and p42 MAP kinases. J. Biol. Chem. 272 (1997) 13397-13402