Scale-up trials of foam-granulation technology - High shear

Pharmaceutical Technology

Volumn 31, Issue 4, 2007, Pages 94-108

  Sheskey, Paul ^a   Keary, Colin ^b   Clark, Dan ^b   Balwinski, Karen ^b  

^a DOW CHEMICAL COMPANY   (United States)

^b NONE

Author keywords

Foam binder; High shear granulation; Scale up; Tableting

Indexed keywords

BATCH DATA PROCESSING; FOAMS; MANUFACTURE; SCALABILITY; TESTING;

FOAM BINDER; HIGH SHEAR GRANULATION; TABLETING;

GRANULATION;

CROSCARMELLOSE SODIUM; LACTOSE; MAGNESIUM STEARATE; METHYLCELLULOSE; MICROCRYSTALLINE CELLULOSE; NAPROXEN;

BATCH PROCESS; CONTINUOUS PROCESS; CONTROLLED RELEASE FORMULATION; DRUG GRANULATION; DRUG MANUFACTURE; FOAM; REVIEW; SCALE UP; SHEAR RATE; TABLET MANUFACTURE; TECHNOLOGY;

EID: 34247248891     PISSN: 15432521     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (10)

1. "Niro Pharma Systems - History," http://www.collette.be, accessed Dec. 22, 2006.
2. Various papers presented at Advances in Wet Granulation Technology for Solid Oral Dosage Forms, AAPS Pharmaceutical Technologies Summer Conference, Lansdowne, VA, June 8-13, 2003.
3. M. Bardin, P.C. Knight, and J.P.K. Seville, "On Control of Particle Size Distribution in Granulation Using High-Shear Mixers," Powder Technol. 140, 169-175 (2004).
4. C.M. Keary and P.J. Sheskey, "Preliminary Report of the Discovery of a New Pharmaceutical Granulation Process Using Foamed Aqueous Binders," Drug Dev. Ind. Pharm. 30 (8), 831-845 (2004).
5. T. Hlinak, "Granulation and Scale-up Issues in Solid Dosage Form Development," Am. Pharm. Rev. 3 (4), 33-36 (2000).
6. M. Yasumura and K. Ashihara, "Scale-up of Oral Solid Dosage Forms," Pharm. Technol. Japan 12 (9), 1279-1289 (1996).
7. E. Russo, "Typical Scale-up Problems and Experiences," Pharm. Technol. 8 (11), 46-48, 50-51, 54-56 (1984).
8. K. Ashihara and M. Yasumura, "Scale-Up for Solid Drugs as Illustrated by Scale-Up of a Granulation Process," Kagaku Kogaku 60 (3), 180-182 (1996).
9. P. Sheskey, C. Keary, and D. Clark, "Foam Granulation: Scale-up of Immediate Release and Controlled Release Formulations from Laboratory Scale to Manufacturing Scale," poster presented at the 2006 Annual Meeting and Exposition of the American Association of Pharmaceutical Scientists, San Antonio, TX, USA, Oct. 29-Nov. 2, 2006.
10. H. Leuenberger, "New Trends in the Production of Pharmaceutical Granules: The Classic Batch Concept and the Problem of Scale-Up," Eur. J. of Pharm. and Biopharm 52, 279-288 (2001).