Reply: Loss-of-function genetic diseases and the concept of pharmaceutical targets [2]

Nature Reviews Genetics

Volumn 8, Issue 5, 2007, Pages

  Brinkmann, Ryan R ^a   Dubé, Marie Pierre ^a   Rouleau, Guy A ^a   Orr, Andrew C ^a   Samuels, Mark E ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

G PROTEIN COUPLED RECEPTOR; LEPTIN; LEPTIN RECEPTOR;

BIPOLAR DISORDER; DRUG INDUSTRY; DRUG MECHANISM; DRUG TARGETING; GENE FUNCTION; GENE MUTATION; GENETIC DISORDER; GENOME ANALYSIS; HYPERTENSION; HYPOTENSION; LETTER; MIGRAINE; MOLECULAR BIOLOGY; MONOGENIC DISORDER; NULL ALLELE; OBESITY; OLFACTORY RECEPTOR; PATHOPHYSIOLOGY; PHENOTYPE; PRIORITY JOURNAL; RECEPTOR GENE; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 34247243118     PISSN: 14710056     EISSN: 14710064     Source Type: Journal    
DOI: None     Document Type: Letter

References (2)

1. Ahituv, N. et al. Medical sequencing at the extremes of human body mass. Am. J. Hum. Genet. 80, 779-791 (2007).
2. Cohen, J. C. et al. Multiple rare alleles contribute to low plasma levels of HDL cholesterol. Science 305, 869-872 (2004).