Effects of 5-hydroxytryptamine on electrical responses of circular smooth muscle isolated from the guinea-pig gastric antrum

Journal of Smooth Muscle Research

Volumn 42, Issue 6, 2006, Pages 203-216

  Kim, Young Chul ^a   Hayase, Masa ^b   Nakamura, Eri ^b   Kito, Yoshihiko ^b   Suzuki, Hikaru ^b  

^a Chungbuk National University College of Medicine   (South Korea)

^b NAGOYA CITY UNIV MEDICAL SCHOOL   (Japan)

Author keywords

5 hydroxytryptamine; ATP sensitive K channel; Gastric muscle; Hyperpolarization; Slow potential

Indexed keywords

ANTIARRHYTHMIC AGENT; ATROPINE; CHOLINERGIC RECEPTOR BLOCKING AGENT; ENZYME INHIBITOR; GLIBENCLAMIDE; METHYSERGIDE; N(G) NITROARGININE; POTASSIUM; SEROTONIN; SEROTONIN ANTAGONIST; SEROTONIN RECEPTOR AFFECTING AGENT;

ANIMAL; ARTICLE; CELL MEMBRANE POTENTIAL; DRUG EFFECT; ELECTROPHYSIOLOGY; GUINEA PIG; IN VITRO STUDY; INNERVATION; MALE; MYENTERIC PLEXUS; PHYSIOLOGY; SMOOTH MUSCLE; STOMACH ANTRUM;

ANIMALS; ANTI-ARRHYTHMIA AGENTS; ATROPINE; ELECTROPHYSIOLOGY; ENZYME INHIBITORS; GLYBURIDE; GUINEA PIGS; MALE; MEMBRANE POTENTIALS; METHYSERGIDE; MUSCLE, SMOOTH; MYENTERIC PLEXUS; NITROARGININE; PARASYMPATHOLYTICS; POTASSIUM; PYLORIC ANTRUM; SEROTONIN; SEROTONIN AGENTS; SEROTONIN ANTAGONISTS;

EID: 34247238310     PISSN: 09168737     EISSN: None     Source Type: Journal    
DOI: 10.1540/jsmr.42.203     Document Type: Article

References (35)

1. Baxter, G.S., Craig, D.A. and Clarke, D.E. (1991). 5-Hydroxytryptamine4 receptors mediate relaxation of the rat oesophageal tunica muscularis mucosae. Naunyn-Schmiedeberg's Arch. Pharmacol. 343: 439-446.
2. Bradley, P.B., Engel, G., Feniuk, W., Fozard, J.R., Humphrey, P.P., Middlemiss, D.N., Mylecharane, E.J., Richardson, B.P. and Saxena, P.R. (1986). Proposal for the classification and nomenclature of functional receptors for 5-hydroxytryptamine. Neuropharmacol. 25: 563-576.
3. Cousins, H.M., Edwards, F.R., Hickey, H., Hill, C.E. and Hirst, G.D.S. (2003). Electrical coupling between the myenetric interstitial cells of Cajal and adjacent muscle layers in the guinea-pig gastric antrum. J. Physiol. (Lond.) 550: 829-844.
4. Dickens, E.J., Hirst, G.D.S. and Tomita, T. (1999). Identification of rhythmically active cells in guinea-pig stomach. J. Physiol. (Lond.) 514: 515-531.
5. Dickens, E.J., Edwards, F.R. and Hirst, G.D.S. (2001). Selective knockout of intramural interstitial cells reveals their role in the generation of slow waves in mouse stomach. J. Physiol. (Lond.) 531: 827-833.
6. Edwards, F.R., Hirst, G.D.S. and Suzuki, H. (1999). Unitary nature of regenerative potentials recorded from circular smooth muscle of guinea-pig antrum. J. Physiol. (Lond.) 519: 235-250.
7. Fukuta, H., Kito, Y. and Suzuki, H. (2002). Spontaneous electrical activity and associated changes in calcium concentration in guinea-pig gastric smooth muscle. J. Physiol. (Lond.) 540: 249-260.
8. 4 receptor-mediated facilitation of fast synaptic transmission in the guinea-pig ileum myenteric plexus. Neurogastroenterol. Motil. 15: 523-529.
9. Gershon, M.D. (2004). Serotonin receptors and transporters-roles in normal and abnormal gastrointestinal motility. Aliment. Pharmacol. Ther. 20 (Suppl. 7): 3-14.
10. Grider, J.R. (2003). Neurotransmitters mediating the intestinal peristaltic reflex in the mouse. J. Pharmacol. Exp. Ther. 307: 460-467.
11. 4 receptor agonists initiate the peristaltic reflex in human, rat, and guinea pig intestine. Gastroenterol. 115: 370-380.
12. - channels. J. Physiol. (Lond.) 540: 907-919.
13. Hirst, G.D.S. and Ward, S.M. (2003). Interstitial cells: involvement in rhythmicity and neural control of gut smooth muscle. J. Physiol. (Lond.) 550: 337-346.
14. Huizinga, J.L., Thuneberg, L., Kluppel, M., Malysz, J., Mikkelsen, H.B. and Bernstein, A. (1995). W/kit gene required for interstitial cells of Cajal and for intestinal pacemaker activity. Nature 373: 347-349.
15. Huizinga, J.L., Thuneberg, L., Vanderwinden, J.M. and Rumessen, J.J. (1997). Interstitial cells of Cajal as targets for pharmacological intervention in gastrointestinal motor disorders. Trends Pharmacol. Sci. 8: 393-403.
16. 4 receptor stimulation on basal and electrically evoked release of acetylcholine from guinea-pig myenteric plexus. Naunyn-Schmiedeberg's Arch. Pharmacol. 345: 270-275.
17. Kito, Y., Fukuta, H., Yamamoto, Y. and Suzuki, H. (2002). Excitation of smooth muscles isolated from the guinea-pig gastric antrum in response to depolarization. J. Physiol. (Lond.) 543: 155-167.
18. Kito, Y. and Suzuki, H. (2003). Modulation of slow waves by hyperpolarization with potassium channel openers in antral smooth muscle of the guinea-pig stomach. J. Physiol. (Lond.) 548: 175-189.
19. Lee, K.P., Nakamura, E., So, I., Kim, K.W. and Suzuki, H. (2004). Role of protein kinase C in the excitatory action of cholinergic nerve stimulation on spontaneous activity of circular smooth muscle isolated from the guinea-pig stomach antrum. Pflügers Arch. 448: 629-637.
20. 4 receptors in the mouse enteric nervous system. Am. J. Physiol. 289: G1148-G1163.
21. Nakamura, E., Lee, K.P., So. I., Kim, K.W. and Suzuki, H. (2004). Effects of endogenous and exogenous nitric oxide on electrical responses of circular smooth muscle isolated from the guinea-pig stomach antrum. J. Smooth Muscle Res. 40: 183-198.
22. Nose, K., Suzuki, H. and Kannan, H. (2000). Voltage-dependency of the frequency of slow waves in antrum smooth muscle of the guinea-pig stomach. Jpn. J. Physiol. 50: 625-633.
23. Ohno, N., Zhang, G., Xue, L., Yamamoto, Y., Itoh, M. and Suzuki, H. (1995). Excitation and inhibition by cisapride of spontaneous and evoked electrical responses in smooth muscles of guinea-pig stomach. Comp. Biochem. Physiol. 112C: 145-152.
24. 4 receptors mediate inhibition and facilitation of fast synaptic transmission in enteric neurons. Am. J. Physiol. 266: G230-G238.
25. Sanders, K.M. (1996). A case for interstitial cells of Cajal as pacemakers and mediators of neurotransmission in the gastrointestinal tract. Gastroenterol. 111: 492-515.
26. Sanders, K.M., Ördög, T., Koh, S.D., Torihashi, S. and Ward, S.M. (1999). Development and plasticity of interstitial cells of Cajal. Neurogastroenterol. Motil. 11: 311-338.
27. Suzuki, H. (2000). Cellular mechanisms of myogenic activity in gastric smooth muscle. Jpn. J. Physiol. 50: 289-301.
28. Suzuki, H. and Hirst, G.D.S. (1999). Regenerative potentials evoked in circular smooth muscle of the antral region of guinea-pig stomach. J. Physiol. (Lond.) 517: 563-573.
29. Suzuki, H., Kito, Y., Fukuta, H. and Yamamoto, Y. (2002). Effects of RHC-80267, an inhibitor of diacylglycerol lipase, on excitation of circular smooth muscle of the guinea-pig gastric antrum. J. Smooth Muscle Res. 38: 153-164.
30. Suzuki, H., Ward, S.M., Bayguinov, Y.R., Edwards, F.R. and Hirst, G.D.S. (2003). Involvement of intramuscular interstitial cells in nitrergic inhibition in the mouse gastric antrum. J. Physiol. (Lond.) 546: 751-763.
31. Taniyama, K., Nakayama, S., Takeda, K., Matsuyama, S., Shirakawa, J., Sano, I. and Tanaka, C. (1991). Cisapride stimulates motility of the intestine via 5-hydroxytryptamine receptors. J. Pharmacol. Exp. Ther. 258: 1098-1104.
32. Teramoto, N. and Hirst, G.D.S. (2003). Interaction between excitatory and inhibitory metabotrophic pathways in the guinea-pig antrum. J. Physiol. (Lond.) 550: 181-189.
33. 4 receptor antagonist, GR 113808. Br. J. Pharmacol. 113: 172P.
34. Tomita, T. (1981). Electrical activity (spikes and slow wave) in gastrointestinal smooth muscles. In: Smooth Muscle, ed. by E. Bülbring, A.F. Brading, A.W. Jones, and T. Tomita, Edward Arnold, London, pp. 127-156.
35. Ward, S.M., Burns, A.J., Torihashi, S. and Sanders, K.M. (1994). Mutation of the proto-oncogene c-kit blocks development of interstitial cells and electrical rhythmicity in murine intestine. J. Physiol. (Lond.) 480: 91-97.