Achiral and chiral high-performance liquid chromatographic determination of flubendazole and its metabolites in biomatrices using UV photodiode-array and mass spectrometric detection

Journal of Chromatography A

Volumn 1149, Issue 1, 2007, Pages 112-120

  Nobilis, Milan ^a   Jira, Thomas ^b   Lísa, Miroslav ^c   Holčapek, Michal ^c   Szotáková, Barbora ^d   Lamka, Jiří ^d   Skálová, Lenka ^d  

^a PROMEDCS Praha as   (Czech Republic)

^b UNIVERSITY OF GREIFSWALD   (Germany)

^c UNIVERSITY OF PARDUBICE   (Czech Republic)

^d Charles University in Prague Faculty of Pharmacy   (Czech Republic)

Author keywords

Achiral and chiral HPLC DAD MS; Benzimidazole anthelmintics; Phase I flubendazole biotransformation; Pheasant; Pig

Indexed keywords

BIOMETRICS; ESTERS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLITES; PHOTODIODES;

ACHIRAL AND CHIRAL HPLC-DAD-MS; BENZIMIDAZOLE ANTHELMINTICS; PHASE I FLUBENDAZOLE BIOTRANSFORMATION; PHEASANT; PIG;

DRUG PRODUCTS;

ACETONITRILE; ALBENDAZOLE; BENZIMIDAZOLE DERIVATIVE; CARBONYL DERIVATIVE; DIMETHYL ETHER; DRUG METABOLITE; FLUBENDAZOLE; MEBENDAZOLE; SODIUM CHLORIDE;

ANIMAL TISSUE; ARTICLE; BIOTRANSFORMATION; CHIRALITY; DECARBOXYLATION; DRUG DETERMINATION; ENANTIOMER; FLOW RATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROLYSIS; INTESTINE; LIVER MICROSOME; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; REDUCTION; STEREOSPECIFICITY; SWINE; VETERINARY MEDICINE;

ANIMALS; ANTHELMINTICS; BIRDS; CALIBRATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; MEBENDAZOLE; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTROPHOTOMETRY, ULTRAVIOLET; STEREOISOMERISM; SWINE; TANDEM MASS SPECTROMETRY;

SUIDAE;

EID: 34247224798     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2007.01.013     Document Type: Article

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