Effect of testicular ischemia-reperfusion on recruitment of neutrophils, E-selectin expression and germ cell apoptosis in the contralateral testis in a rat

Pediatric Surgery International

Volumn 23, Issue 5, 2007, Pages 479-485

  Sukhotnik, Igor ^a   Voskoboinik, Katya ^a   Lurie, Michael ^a   Coran, Arnold G ^c   Greenblatt, Robert ^a   Shiloni, Eitan ^b   Eldar, Samuel ^a   Mogilner, Jorge G ^a  

^a TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

^b CARMEL MEDICAL CENTER   (Israel)

^c UNIVERSITY OF MICHIGAN   (United States)

Author keywords

E selectin; Germ cell apoptosis; Ischemia reperfusion; Neutrophil recruitment; Testis

Indexed keywords

ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; CALCULATION; CONFERENCE PAPER; CONTROLLED STUDY; GERM CELL; IMMUNOHISTOCHEMISTRY; ISCHEMIA; MALE; NEUTROPHIL; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REPERFUSION INJURY; SPERMATOGENESIS; STATISTICAL SIGNIFICANCE; STUDENT T TEST; TESTIS; TESTIS INJURY;

ANIMALS; APOPTOSIS; DISEASE MODELS, ANIMAL; E-SELECTIN; GENE EXPRESSION; GERM CELLS; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; MALE; NEUTROPHIL INFILTRATION; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY; SPERMATOGENESIS; TESTICULAR DISEASES; TESTIS;

EID: 34247221055     PISSN: 01790358     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00383-006-1854-x     Document Type: Conference Paper

References (19)

1. Said TM, Paasch U, Glander HJ, Agarwal A (2004) Role of caspases in male infertility. Hum Reprod Update 10:39-51
2. Majno G, Joris I (1995) Apoptosis, oncosis and necrosis. An overview of cell death. Am J Pathol 146:3-15
3. Sukhotnik I, Bernshtein A, Mogilner JG (2005) The basic biology of apoptosis and its implications for pediatric surgery. Eur J Pediatr Surg 15:229-235
4. Turner TT, Tung KS, Tomomasa H, Wilson LW (1997) Acute testicular ischemia results in germ cell-specific apoptosis in the rat. Biol Reprod 57:1267-1274
5. Lysiak JJ, Turner SD, Turner TT (2000) Molecular pathway of germ cell apoptosis following ischemia/reperfusion of the rat testis. Biol Reprod 63:1475-1482
6. Lysiak JJ, Turner SD, Nguyen QAT, Singbartl K, Ley K, Turner TT (2001) Essential role of neutrophils in germ cell-specific apoptosis following ischemia/reperfusion injury of the mouse testis. Biol Reprod 65:718-725
7. Sukhotnik I, Miselevich I, Lurie M, Nativ O, Coran AG, Mogilner JG (2005) The time relationship between ipsilateral testicular ischemia-reperfusion and germ cell apoptosis in the contralateral testis in rat. Pediatr Surg Int 15:1-5
8. Mogilner J, Elenberg I, Lurie M, Shiloni E, Coran AG, Sukhotnik I (2006) Effect of dexamethasone on germ cell apoptosis in the contralateral testis following testicular ischemia-reperfusion injury in the rat. Fertil Steril 85(suppl 1): 1111-1117
9. Miller DC, Peron SE, Keck RW, Kropp KA (1990) Effects of hypothermia on testicular ischemia. J Urol 143:1046-1048
10. Johnsen SG (1970) Testicular biopsy score count - a method for registration of spermatogenesis in human testes: normal values and results in 335 hypogonadal males. Hormones 1:2-25
11. Bartsch G, Frank S, Marberger H, Mikuz G (1980) Testicular torsion: late results with special regard to fertility and endocrine function. J Urol 124:375-378
12. Krasik EF, Yee KL, Hammer DA (2006) Adhesive Dynamics simulation of neutrophil arrest with deterministic activation. Biophys J 91:1145-1155
13. McMeekin SR, Dransfield I, Rossi AG, Haslett C, Walker TR (2006) E-selectin permits communication between PAF receptors and TRPC channels in human neutrophils. Blood 107:4938-4945
14. Lawrence MB, Springer TA (1993) Neutrophils roll on E-selectin. JImmunol 151:6338-6346
15. Simon SI, Cherapanov V, Nadra I, Waddell TK, Seo SM, Wang Q, Doerschuk CM, Downey GP (1999) Signaling functions of L-selectin in neutrophils: alterations in the cytoskeleton and colocalization with CD18. J Immunol 163:2891-2901
16. Serhan CN, Savill J (2005) Resolution of inflammation: the beginning programs the end. Nat Immunol 6:1191-1197
17. Lysiak JJ, Nguyen QA, Turner TT (2002) Peptide and nonpeptide reactive oxygen scavengers provide partial rescue of the testis after torsion. J Androl 23:400-409
18. Puri P, Barton D, O'Donnell B (1985) Prepubertal testicular torsion:subsequent fertility. J Pediatr Surg 20:598-601
19. Lysiak JJ, Nguyen QA, Kirby JL, Turner TT (2003) Ischemia-reperfusion of the murine testis stimulates the expression of proinflammatory cytokines and activation of c-jun N-terminal kinase in a pathway to E-selectin expression. Biol Reprod 69:202-210