Determination of valproic acid in human serum and pharmaceutical preparations by headspace liquid-phase microextraction gas chromatography-flame ionization detection without prior derivatization

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 850, Issue 1-2, 2007, Pages 128-133

  Shahdousti, Parvin ^a   Mohammadi, Abdorreza ^a   Alizadeh, Naader ^a  

^a TARBIAT MODARES UNIVERSITY   (Iran)

Author keywords

Gas chromatography; Headspace liquid phase microextraction; Human serum analysis; Pharmaceutical preparations; Valproic acid

Indexed keywords

BLOOD; EXTRACTION; GAS CHROMATOGRAPHY; IONIC STRENGTH; IONIZATION; ORGANIC SOLVENTS;

HEADSPACE LIQUID PHASE MICROEXTRACTION; HUMAN SERUM ANALYSIS; PHARMACEUTICAL PREPARATIONS; VALPROIC ACID;

PHARMACOKINETICS;

DODECANE; ORGANIC SOLVENT; VALPROIC ACID;

ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DERIVATIZATION; DRUG DETERMINATION; GAS CHROMATOGRAPHY; HUMAN; IONIC STRENGTH; LIQUID PHASE MICROEXTRACTION; PH MEASUREMENT; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SUSTAINED RELEASE PREPARATION; SYRINGE; TEMPERATURE SENSITIVITY;

ANTICONVULSANTS; CHROMATOGRAPHY, GAS; HUMANS; HYDROGEN-ION CONCENTRATION; OSMOLAR CONCENTRATION; PHARMACEUTICAL PREPARATIONS; SENSITIVITY AND SPECIFICITY; SOLVENTS; VALPROIC ACID;

EID: 34247196690     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2006.11.013     Document Type: Article

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