Case 12-2007: A 56-year-old woman with renal failure after heart-lung transplantation

New England Journal of Medicine

Volumn 356, Issue 16, 2007, Pages 1657-1665

  Goes, Nelson B ^a,b   Colvin, Robert B ^a,b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALUMINUM HYDROXIDE; AZATHIOPRINE; CLOTRIMAZOLE; CYCLOSPORIN; FOLIC ACID; FUROSEMIDE; HYDRALAZINE; MULTIVITAMIN; NIFEDIPINE; POTASSIUM; PREDNISONE; RETINOL; TRIMETHOPRIM; IMMUNOSUPPRESSIVE AGENT;

ADULT; ANAMNESIS; ARTICLE; CASE REPORT; CHRONIC KIDNEY DISEASE; CHRONIC KIDNEY FAILURE; CLINICAL FEATURE; DIABETIC NEPHROPATHY; DIAGNOSTIC PROCEDURE; DIFFERENTIAL DIAGNOSIS; FEMALE; GLOMERULOPATHY; HEART LUNG TRANSPLANTATION; HOSPITAL ADMISSION; HUMAN; PRIORITY JOURNAL; CHEMICALLY INDUCED DISORDER; CLINICAL OBSERVATION; CLINICAL STUDY; DIAGNOSIS; FOCAL GLOMERULOSCLEROSIS; HYPERTENSION; KIDNEY; MIDDLE AGED; PATHOLOGY; PULMONARY HYPERTENSION;

CYCLOSPORINE; DIAGNOSIS, DIFFERENTIAL; FEMALE; GLOMERULOSCLEROSIS, FOCAL SEGMENTAL; HEART-LUNG TRANSPLANTATION; HUMANS; HYPERTENSION; HYPERTENSION, PULMONARY; IMMUNOSUPPRESSIVE AGENTS; KIDNEY; KIDNEY FAILURE, CHRONIC; MIDDLE AGED;

EID: 34247195042     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMcpc079008     Document Type: Article

References (30)

1. Ojo AO, Held PJ, Port FK, et al. Chronic renal failure after transplantation of a nonrenal organ. N Engl J Med 2003;349:931-40.
2. Kasiske BL, Snyder JJ, Gilbertson D, Matas AJ. Diabetes mellitus after kidney transplantation in the United States. Am J Transplant 2003;3:178-85.
3. Cattran DC, Pei Y, Greenwood C. Predicting progression in membranous glomerulonephritis. Nephrol Dial Transplant 1992;7:Suppl 1:48-52.
4. Mylonakis E, Goes N, Rubin RH, Cosimi AB, Colvin RB, Fishman JA. BK virus in solid organ transplant recipients: an emerging syndrome. Transplantation 2001;72:1587-92.
5. Menahem SA, McDougall KM, Thomson NM, Dowling JP. Native kidney BK nephropathy post cardiac transplantation. Transplantation 2005;79:259-60.
6. Milstone A, Vilchez RA, Geiger X, Fogo AB, Butel JS, Dummer S. Polyomavirus simian virus 40 infection associated with nephropathy in a lung-transplant recipient. Transplantation 2004;77:1019-24.
7. Lipshutz GS, Mahanty H, Feng S, et al. BKV in simultaneous pancreas-kidney transplant recipients: a leading cause of renal graft loss in first 2 years post-transplant. Am J Transplant 2005;5:366-73.
8. Choi HK, Merkel PA, Walker AM, Niles JL. Drug-associated antineutrophil cytoplasmic antibody-positive vasculitis: prevalence among patients with high titers of antimyeloperoxidase antibodies. Arthritis Rheum 2000;43:405-13.
9. Pascual M, Theruvath T, Kawai T, Tolkoff-Rubin N, Cosimi AB. Strategies to improve long-term outcomes after renal transplantation. N Engl J Med 2002;346:580-90.
10. Halloran PF. Immunosuppressive drugs for kidney transplantation. N Engl J Med 2004;351:2715-29. [Erratum, N Engl J Med 2005;352:1056.]
11. Nankivell BJ, Borrows RJ, Fung CL, O'Connell PJ, Allen RDM, Chapman JR. Evolution and pathophysiology of renaltransplant glomerulosclerosis. Transplantation 2004;78:461-8.
12. Idem. The natural history of chronic allograft nephropathy. N Engl J Med 2003;349:2326-33.
13. Prashar Y, Khanna A, Sehajpal P, Sharma VK, Suthanthiran M. Stimulation of transforming growth factor-beta 1 transcription by cyclosporine. FEBS Lett 1995;358:109-12.
14. D'Agati VD, Fogo AB, Bruijn JA, Jennette JC. Pathologic classification of focal segmental glomerulosclerosis: a working proposal. Am J Kidney Dis 2004;43:368-82.
15. Weiss MA, Daquioag E, Margolin EG, Pollak VE. Nephrotic syndrome, progressive irreversible renal failure, and glomerular "collapse": a new clinicopathologic entity? Am J Kidney Dis 1986;7:20-8.
16. Markowitz GS, Appel GB, Fine PL, et al. Collapsing focal segmental glomerulosclerosis following treatment with high-dose pamidronate. J Am Soc Nephrol 2001;12:1164-72.
17. Moudgil A, Nast CC, Bagga A, et al. Association of parvovirus B19 infection with idiopathic collapsing glomerulopathy. Kidney Int 2001;59:2126-33.
18. Nadasdy T, Allen C, Zand MS. Zonal distribution of glomerular collapse in renal allografts: possible role of vascular changes. Hum Pathol 2002;33:437-41.
19. Stokes MB, Davis CL, Alpers CE. Collapsing glomerulopathy in renal allografts: a morphological pattern with diverse clinicopathologic associations. Am J Kidney Dis 1999;33:658-66.
20. Barisoni L, Kriz W, Mundel P, D'Agati V. The dysregulated podocyte phenotype: a novel concept in the pathogenesis of collapsing idiopathic focal segmental glomerulosclerosis and HIV-associated nephropathy. J Am Soc Nephrol 1999;10:51-61.
21. Shankland SJ, Eitner F, Hudkins KL, Goodpaster T, D'Agati V, Alpers CE. Differential expression of cyclin-dependent kinase inhibitors in human glomerular disease: role in podocyte proliferation and maturation. Kidney Int 2000;58:674-83.
22. Barisoni L, Mokrzycki M, Sablay L, Nagata M, Yamase H, Mundel P. Podocyte cell cycle regulation and proliferation in collapsing glomerulopathies. Kidney Int 2000;58:137-43.
23. Nizze H, Mihatsch MJ, Zollinger HU, et al. Cyclosporine-associated nephropathy in patients with heart and bone marrow transplants. Clin Nephrol 1988;30:248-60.
24. Myers BD, Sibley R, Newton L, et al. The long-term course of cyclosporineassociated chronic nephropathy. Kidney Int 1988;33:590-600.
25. Dische FE, Neuberger J, Keating J, Parsons V, Calne RY, Williams R. Kidney pathology in liver allograft recipients after long-term treatment with cyclosporin A. Lab Invest 1988;58:395-402.
26. Cosio FG, Frankel WL, Pelletier RP, Pesavento TE, Henry ML, Ferguson RM. Focal segmental glomerulosclerosis in renal allografts with chronic nephropathy: implications for graft survival. Am J Kidney Dis 1999;34:731-8.
27. Meehan SM, Pascual M, Williams WW, et al. De novo collapsing glomerulopathy in renal allografts. Transplantation 1998;65:1192-7.
28. Colvin RB, Nickeleit V. Renal transplant pathology. In: Jennette JC, Olson JL, Schwartz MM, Silva FG, eds. Heptinstall's pathology of the kidney. 6th ed. Philadelphia: Lippincott-Raven, 2006:1347-490.
29. Mihatsch MJ, Morozumi K, Strom EH, Ryffel B, Gudat F, Thiel G. Renal transplant morphology after long-term therapy with cyclosporine. Transplant Proc 1995;27:39-42.
30. Randhawa PS, Shapiro R, Jordan ML, Starzl TE, Demetris AJ. The histopathological changes associated with allograft rejection and drug toxicity in renal transplant recipients maintained on FK506: clinical significance and comparison with cyclosporine. Am J Surg Pathol 1993;17:60-8.