Copper(II) bromide: A simple and selective monobromination reagent for electron-rich aromatic compounds

Synthetic Communications

Volumn 37, Issue 8, 2007, Pages 1381-1388

  Bhatt, Suchitra ^a   Nayak, Sandip K ^a  

^a BHABHA ATOMIC RESEARCH CENTRE   (India)

Author keywords

Anilines; Aryl alkyl ethers; Bromination; Copper(II) bromide; Phenols

Indexed keywords

ALKYL ARYL ETHER; AROMATIC AMINE; AROMATIC COMPOUND; CUPRIC BROMIDE; PHENOL; UNCLASSIFIED DRUG;

ARTICLE; BROMINATION; CHEMICAL REACTION; ELECTRON; ROOM TEMPERATURE;

EID: 34247174888     PISSN: 00397911     EISSN: 15322432     Source Type: Journal    
DOI: 10.1080/00908320701230026     Document Type: Article

References (6)

1. Fort, A. W. Reactions of some organic compounds with cupric bromide. J. Org. Chem. 1961, 26, 765-767.
2. Castro, C. E.; Gaughan, E. J.; Owsley, D. C. Cupric halide halogenation. J. Org. Chem. 1965, 30, 587-592.
3. (a) Kovacic, P.; Davis, K. E. Cupric bromide and alkylbenzenes: Influence of water on nuclear bromination vs side chain attack. J. Am. Chem. Soc. 1964, 86, 427-432;
4. (b) Kodomari, M.; Satoh, H.; Yoshotomi, S. Selective nuclear halogenation of polymethylbenzenes with alumina-supported copper(II) halides. Bull. Chem. Soc. Jpn. 1988, 61, 4149-4150;
5. (c) Ware, J. C.; Borchert, E. E. Chlorination of aromatic hydrocarbons by cupric halide. J. Org. Chem. 1961, 26, 2263-2267.
6. Semwal, A.; Nayak, S. K. Copper(II) bromide-catalyzed imino Diels-Alder reaction: Synthesis of pyrano[3,2-c]- and furo[3,2-c]tetrahydroquinolines. Synth. Commun. 2006, 36, 227-236.