Calcineurin-independent inhibition of the delayed rectifier K+ current by the immunosuppressant FK506 in rat hippocampal neurons

Brain Research

Volumn 1148, Issue 1, 2007, Pages 62-68

  Yu, Yong ^a   Chen, Xue Qin ^b   Cui, Yao Yuan ^a   Hu, Guo Yuan ^b  

^a FUDAN UNIVERSITY   (China)

^b SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

Calcineurin; Cyclosporin A; Delayed rectifier K+ channel; Fast transient K+ channel; FK506; Hippocampus; Immunosuppressant drug; Rapamycin

Indexed keywords

CALCINEURIN; CYCLOSPORIN A; IMMUNOSUPPRESSIVE AGENT; PHOSPHATASE; RAPAMYCIN; TACROLIMUS; VOLTAGE GATED POTASSIUM CHANNEL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELLULAR DISTRIBUTION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DEPOLARIZATION; DIALYSIS; DISSOCIATION; DRUG ANTAGONISM; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; HIPPOCAMPUS; IC 50; NEUROPROTECTION; NONHUMAN; POTASSIUM CURRENT; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT; STEADY STATE;

ANIMALS; ANIMALS, NEWBORN; BRAIN ISCHEMIA; CALCINEURIN; DOSE-RESPONSE RELATIONSHIP, DRUG; HIPPOCAMPUS; IMMUNOSUPPRESSIVE AGENTS; ION CHANNEL GATING; MEMBRANE POTENTIALS; NEURAL INHIBITION; NEURONS; NEUROPROTECTIVE AGENTS; ORGAN CULTURE TECHNIQUES; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; PYRAMIDAL CELLS; RATS; RATS, SPRAGUE-DAWLEY; TACROLIMUS;

ANIMALIA; RATTUS;

EID: 34247152581     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2007.02.022     Document Type: Article

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