Portable optical spectroscopy for accurate analysis of ethane in exhaled breath

Measurement Science and Technology

Volumn 18, Issue 5, 2007, Pages 1459-1464

  Patterson, Claire S ^a   McMillan, Lesley C ^b   Longbottom, Christopher ^b   Gibson, Graham M ^a   Padgett, Miles J ^a   Skeldon, Kenneth D ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

Breath; Ethane; Infrared; Oxidative stress

Indexed keywords

COMPUTER SOFTWARE; COOLANTS; EMISSION SPECTROSCOPY; INFRARED RADIATION; OXIDATIVE STRESS; SEMICONDUCTOR LASERS;

BREATH; LIQUID COOLANTS; PORTABLE OPTICAL SPECTROSCOPY;

ETHANE;

COMPUTER SOFTWARE; COOLANTS; EMISSION SPECTROSCOPY; ETHANE; INFRARED RADIATION; OXIDATIVE STRESS; SEMICONDUCTOR LASERS;

EID: 34247135081     PISSN: 09570233     EISSN: 13616501     Source Type: Journal    
DOI: 10.1088/0957-0233/18/5/035     Document Type: Article

References (18)

1. Hoheisel M 2006 Review of medical imaging with emphasis on X-ray detectors Nucl. Instrum. Methods A 563 215-24
2. Huttmann G, Yao C and Endl E 2005 New concepts in laser medicine: towards a laser surgery with cellular precision Med. Laser Appl. 20 135-9
3. Miekisch W, Vagts D A, Schubert J K and Geiger K 2001 Analysis of volatile disease markers in blood Clin. Chem. 47 1053-60
4. Risby T H and Sehnert S S 1999 Clinical application of breath biomarkers of oxidative stress status Free Rad. Biol. Med. 27 1182-92
5. Miekisch W, Noeldge-Schomburg G F E and Schubert J K 2004 Diagnostic potential of breath analysis-focus on volatile organic compounds Clin. Chim. Acta. 347 25-39
6. Aghdassia E and Allard J P 2000 Breath alkanes as a marker of oxidative stress in different clinical conditions Free Rad. Biol. Med. 28 880-6
7. Brown R H and Risby T H 2003 Disease Markers in Exhaled Breath (New York: Dekker) chapter 13
8. Halliwell B and Gutteridge J M C 1999 Free Radicals in Biology and Medicine (Oxford: Oxford Science Publications)
9. Dale O, Bergum H, Lund T, Nilsen T, Aadahl P and Stenseth R 2003 A validated method for rapid analysis of ethane in breath and its application in kinetic studies in human volunteers Free Rad. Res. 37 815-21
10. Skeldon K D, Gibson G M, Wyse C A, McMillan L C, Monk S D, Longbottom C and Padgett M J 2005 Development of high resolution real-time sub-ppb ethane spectroscopy and some pilot studies in life science Appl. Opt. 44 4712-21
11. Skeldon K D, Patterson C, Wyse C A, Gibson G M, Padgett M J, Longbottom C and McMillan L C 2005 The potential offered by real-time, high-sensitivity monitoring of ethane in breath and some pilot studies using optical spectroscopy J. Opt. A: Pure Appl. Opt. 7 S376-84
12. Stothard D J M, Lindsay I D and Dunn M H 2004 Continuous-wave pump-enhanced optical parametric oscillator with ring resonator for wide and continuous tuning of single-frequency radiation Opt. Exp. 12 502-11
13. Richter D, Fried A, Wert B P, Walega J G and Tittel F K 2002 Development of a tunable mid-IR difference frequency laser source for highly sensitive airborne trace gas detection Appl. Phys. B 75 281-8
14. Mueller F, Popp A, Schiller S and Kuehnemann F 2004 Cw-OPO-based photoacoustic spectrometer for highly sensitive detection of ethane and other volatile organic compounds Photons Plus Ultrasound: Imaging and Sensing (Proc. SPIE vol 5320) ed A A Oraevsky and L V Wang pp 138-44
15. von Basum G, Halmer D, Hering P, Mürtz M, Schiller S, Müller, Popp F A and Kühnemann F 2004 Parts per trillion sensitivity for ethane in air with an optical parametric oscillator cavity leak-out spectrometer Opt. Lett. 29 797-9
16. Halmer D, Thelen S, Hering P and Mürtz M 2006 Online monitoring of ethane traces in exhaled breath with a difference frequency generation spectrometer Appl. Phys. B 85 437-43
17. Gibson G, Monk S D and Padgett M 2002 A field-portable, laser-diode spectrometer for the ultra-sensitive detection of hydrocarbon gases J. Mod. Opt. 49 769-76
18. Hirst B, Gibson G, Gillespie S, Archibald I, Podlaha O, Skeldon K D, Courtial J, Monk S and Padgett M 2004 Oil and gas prospecting by ultra-sensitive optical gas detection with inverse gas dispersion modelling Geophys. Res. Lett. 31 L12115