Tube-feeding in advanced dementia. An evidence-based ethical analysis;PEG-ernährung bei fortgeschrittener demenz. Eine evidenzgestützte ethische analyse

Nervenarzt

Volumn 78, Issue 4, 2007, Pages 418-428

  Synofzik, M ^a,b  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

Algorithms; Artificial nutrition; Decision making; Dementia; Ethics; Gastrostomy; Withholding treatment

Indexed keywords

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DECISION MAKING; DEMENTIA; ETHICS; EVIDENCE BASED MEDICINE; HUMAN; TUBE FEEDING;

DEMENTIA; ENTERAL NUTRITION; EVIDENCE-BASED MEDICINE; GERMANY; HUMANS; MENTAL COMPETENCY; PATIENT RIGHTS; PERSONAL AUTONOMY; QUALITY OF LIFE;

EID: 34247119751     PISSN: 00282804     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00115-006-2245-1     Document Type: Article

References (80)

1. Abuksis G, Mor M, Segal N et al. (2000) Percutaneous endoscopic gastrostomy: high mortality rates in hospitalized patients. Am J Gastroenterol 95: 128-132
2. Ahronheim JC, Gasner MR (1990) The sloganism of starvation. Lancet 335: 278-279
3. Alvarez-Fernandez B, Garcia-Ordonez MA et al. (2005) Survival of a cohort of elderly patients with advanced dementia: nasogastric tube feeding as a risk factor for mortality. Int J Geriatr Psychiatry 20: 363-370
4. Beauchamp T, Childress J (2001) Principles of Biomedical Ethics, 5th edn. Oxford Univ Press, New York Oxford
5. Bernat JL, Beresford HR (2006) The controversy over artificial hydration and nutrition. Neurology 66: 1618-1619
6. Bourdel-Marchasson I, Barateau M et al. (2000) A multi-center trial of the effects of oral nutritional supplementation in critically ill older inpatients. GAGE Group. Groupe Aquitain Geriatrique d'Evaluation. Nutrition 16: 1-5
7. Brotherton A, Abbott J, Aggett P (2006) The impact of percutaneous endoscopic gastrostomy feeding upon daily life in adults. J Hum Nutr Diet 19: 355-367
8. Buijssen H (1994) Senile Demenz: eine praktische Anleitung für den Umgang mit Alzheimer-Patienten. Beltz, Weinheim
9. Callahan CM, Haag KM, Buchanan NN, Nisi R (1999) Decision-making for percutaneous endoscopic gastrostomy among older adults in a community setting. J Am Geriatr Soc 47: 1105-1109
10. Callahan CM, Haag KM, Weinberger M et al. (2000) Outcomes of percutaneous endoscopic gastrostomy among older adults in a community setting. J Am Geriatr Soc 48: 1048-1054
11. Carver AC, Vickrey BG, Bernat JL et al. (1999) End-of-life care: a survey of US neurologists' attitudes, behavior, and knowledge. Neurology 53: 284-293
12. Cefalu CA (1999) Appropriate dysphagia evaluation and management of the nursing home patient with dementia. Ann Long Term Care 7: 447-451
13. Chernoff R (2006) Tube feeding patients with dementia. Nutr Clin Pract 21: 142-146
14. Ciment J (2000) Tube feeding bad for patients with dementia. BMJ 320: 335B
15. Deutscher Juristentag (2006) Strafrecht: Patienten-autonomie und Strafrecht bei der Sterbebegleitung. In: 66. Deutscher Juristentag 2006, Stuttgart, http://www.djt.de/index.php.
16. Dharmarajan TS, Unnikrishnan D, Pitchumoni CS (2001) Percutaneous endoscopic gastrostomy and outcome in dementia. Am J Gastroenterol 96: 2556-2563
17. Fagerlin A, Schneider CE (2004) Enough. The failure of the living will. Hastings Cent Rep 34: 30-42
18. Feinberg MJ, Knebl J, Tully J (1996) Prandial aspiration and pneumonia in an elderly population followed over 3 years. Dysphagia 11: 104-109
19. Ferrell BA, Josephson K, Norvid P, Alcorn H (2000) Pressure ulcers among patients admitted to home care. J Am Geriatr Soc 48: 1042-1047
20. Finucane TE (1995) Malnutrition, tube feeding and pressure sores: data are incomplete. J Am Geriatr Soc 43: 447-451
21. Finucane TE, Bynum JP (1996) Use of tube feeding to prevent aspiration pneumonia. Lancet 348: 1421-1424
22. Finucane TE, Christmas C, Travis K (1999) Tube feeding in patients with advanced dementia: a review of the evidence. Jama 282: 1365-1370
23. Finucane TE (2004) Malnutrition and pressure ulcers: data are still incomplete. J Am Geriatr Soc 52: 163; author reply 163-164
24. Ganzini L, Goy ER, Miller LL et al. (2003) Nurses' experiences with hospice patients who refuse food and fluids to hasten death. N Engl J Med 349: 359-365
25. Ganzini L (2006) Artificial nutrition and hydration at the end of life: ethics and evidence. Palliat Support Care 4: 135-143
26. Gillick MR (2000) Rethinking the role of tube feeding in patients with advanced dementia. N Engl J Med 342: 206-210
27. Gossner L, Ludwig J, Hahn EG, Ell C (1995) Risiken der perkutanen endoskopischen Gastronomie. Dtsch Med Wochenschr 120: 1768-1772
28. Harper J, McMurdo ME, Robinson A (1999) Outcomes of percutaneous endoscopic gastrostomy feeding. Age Ageing 28: 497-498
29. Hasan M, Meara RJ, Bhowmick BK, Woodhouse K (1995) Percutaneous endoscopic gastrostomy in geriatric patients: attitudes of health care professionals. Gerontology 41: 326-331
30. Karlawish JH, Casarett D, Klocinski J, Clark CM (2001) The relationship between caregivers' global ratings of Alzheimer's disease patients' quality of life, disease severity, and the caregiving experience. J Am Geriatr Soc 49: 1066-1070
31. Kaw M, Sekas G (1994) Long-term follow-up of consequences of percutaneous endoscopic gastrostomy (PEG) tubes in nursing home patients. Dig Dis Sci 39: 738-743
32. Kreß H (2004) Selbstbestimmung am Lebensende. Die Bioethik-Kommission Rheinland-Pfalz zur Sterbehilfe und Sterbebegleitung. Zeitschrift für Ethik in der Medizin 16: 291-297
33. Kruse A (2005) Lebensqualität demenzkranker Menschen. Zeitschrift für Medizinische Ethik 51: 41-57
34. Lacey D (2004) Tube feeding in advanced Alzheimer's disease: when language misleads. Am J Alzheimers Dis Other Demen 19: 125-127
35. Marckmann G (2000) Was ist eigentlich prinzipienorientierte Medizinethik? Ärzteblatt Baden-Württemberg 55: 499-502
36. Marckmann G (2004) Lebensverlängerung um jeden Preis? Ärzteblt Bad-Württ 59: 379-382
37. Marckmann G (2005) Prinzipienorientierte Medizinethik im Praxistest. In: Rauprich O, Steger F (eds) Prinzipienethik in der Biomedizin. Moralphilosophie und medizinische Praxis. Campus, Frankfurt New York, pp 398-415.
38. McCann RM, Hall WJ, Groth-Juncker A (1994) Comfort care for terminally ill patients. The appropriate use of nutrition and hydration. Jama 272: 1263-1266
39. McCann R (1999) Lack of evidence about tube feeding ? food for thought. Jama 282: 1380-1381
40. McNabney MK, Beers MH, Siebens H (1994) Surrogate decision-makers' satisfaction with the placement of feeding tubes in elderly patients. J Am Geriatr Soc 42: 161-168.
41. Meier DE, Ahronheim JC, Morris J et al. (2001) High short-term mortality in hospitalized patients with advanced dementia: lack of benefit of tube feeding. Arch Intern Med 161: 594-599
42. Mitchell SL, Kiely DK, Lipsitz LA (1997) The risk factors and impact on survival of feeding tube placement in nursing home residents with severe cognitive impairment. Arch Intern Med 157: 327-332
43. Mitchell SL, Lawson FM (1999) Decision-making for long-term tube-feeding in cognitively impaired elderly people. Cmaj 160: 1705-1709
44. Mitchell SL, Berkowitz RE, Lawson FM, Lipsitz LA (2000) A cross-national survey of tube-feeding decisions in cognitively impaired older persons. J Am Geriatr Soc 48: 391-397.
45. Mitchell SL, Kiely DK, Gillick MR (2003) Nursing home characteristics associated with tube feeding in advanced cognitive impairment. J Am Geriatr Soc 51: 75-79
46. Monteleoni C, Clark E (2004) Using rapid-cycle quality improvement methodology to reduce feeding tubes in patients with advanced dementia: before and after study. BMJ 329: 491-494
47. Murphy LM, Lipman TO (2003) Percutaneous endoscopic gastrostomy does not prolong survival in patients with dementia. Arch Intern Med 163: 1351-1353
48. Nair S, Hertan H, Pitchumoni CS (2000) Hypoalbuminemia is a poor predictor of survival after percutaneous endoscopic gastrostomy in elderly patients with dementia. Am J Gastroenterol 95: 133-136
49. Niv Y, Abuksis G (2002) Indications for percutaneous endoscopic gastrostomy insertion: ethical aspects. Dig Dis 20: 253-256
50. Park RH, Allison MC, Lang J et al. (1992) Randomised comparison of percutaneous endoscopic gastrostomy and nasogastric tube feeding in patients with persisting neurological dysphagia. Bmj 304: 1406-1409
51. Pasman HR, The BA, Onwuteaka-Philipsen BD et al. (2003) Feeding nursing home patients with severe dementia: a qualitative study. J Adv Nurs 42: 304-311
52. Pasman HR, Onwuteaka-Philipsen BD, Kriegsman DM et al. (2005) Discomfort in nursing home patients with severe dementia in whom artificial nutrition and hydration is forgone. Arch Intern Med 165: 1729-1735
53. Peck A, Cohen CE, Mulvihill MN (1990) Long-term enteral feeding of aged demented nursing home patients. J Am Geriatr Soc 38: 1195-1198
54. Phillips PA, Rolls BJ, Ledingham JG et al. (1984) Reduced thirst after water deprivation in healthy elderly men. N Engl J Med 311: 753-759
55. Pick N, McDonald A, Bennett N et al. (1996) Pulmonary aspiration in a long-term care setting: clinical and laboratory observations and an analysis of risk factors. J Am Geriatr Soc 44: 763-768.
56. Post S (2000) The Moral Challenge of Alzheimer Disease: Ethical Issues from Diagnosis to Dying. John Hopkins Uni Press, Baltimore
57. Post SG (2001) Tube feeding and advanced progressive dementia. Hastings Cent Rep 31: 36-42
58. Printz LA (1992) Terminal dehydration, a compassionate treatment. Arch Intern Med 152: 697-700
59. Quill TE (1989) Utilization of nasogastric feeding tubes in a group of chronically ill, elderly patients in a community hospital. Arch Intern Med 149: 1937-1941
60. Rabeneck L, Wray NP, Petersen NJ (1996) Longterm outcoes of patients receiving percutaneous endoscopic gastrostomy tubes. J Gen Intern Med 11: 287-293
61. Rabeneck L, McCullough LB, Wray NP (1997) Ethically justified, clinically comprehensive guidelines for percutaneous endoscopic gastrostomy tube placement. Lancet 349: 496-498
62. Ready RE, Ott BR, Grace J (2004) Patient versus informant perspectives of Quality of Life in Mild Cognitive Impairment and Alzheimer's disease. Int J Geriatr Psychiatry 19: 256-265.
63. Rothärmel S (2004) Juristischer Kommentar. Z Ethik Med 16: 289-290
64. Sachs GA (1998) Dementia and the goals of care. J Am Geriatr Soc 46: 782-783
65. Sanders DS, Carter MJ, D'Silva J et al. (2000) Survival analysis in percutaneous endoscopic gastrostomy feeding: a worse outcome in patients with dementia. Am J Gastroenterol 95: 1472-1475
66. Sanders DS, Anderson AJ, Bardhan KD (2004) Percutaneous endoscopic gastrostomy: an effective strategy for gastrostomy feeding in patients with dementia. Clin Med 4: 235-241
67. Scott AG, Austin HE (1994) Nasogastric feeding in the management of severe dysphagia in motor neurone disease. Palliat Med 8: 45-49
68. Shega JW, Hougham GW, Stocking CB et al. (2003) Barriers to limiting the practice of feeding tube placement in advanced dementia. J Palliat Med 6: 885-893
69. Sheiman SL (1996) Tube feeding the demented nursing home resident. J Am Geriatr Soc 44: 1268-1270
70. Simon A (2004) Ethische Aspekte der künstlichen Ernährung bei nichteinwilligungsfähigen Patienten. Z Ethik Med 16: 217-228
71. Solomon MZ, O'Donnell L, Jennings B et al. (1993) Decisions near the end of life: professional views on life-sustaining treatments. Am J Public Health 83: 14-23
72. Steinbrook R, Lo B (1988) Artificial feeding - solid ground, not a slippery slope. N Engl J Med 318: 286-290
73. Strätling M, Schmucker P, Bartmann F-J (2005) Künstliche Ernährung: Gut gmeint ist nicht immer gut gemacht. Deutsches Ärzteblatt 102: A 2153-2154
74. Sullivan RJ Jr (1993) Accepting death without artificial nutrition or hydration. J Gen Intern Med 8: 220-224
75. Sullivan-Marx EM, Strumpf NE, Evans LK et al. (1999) Predictors of continued physical restraint use in nursing home residents following restraint reduction efforts. J Am Geriatr Soc 47: 342-348
76. Synofzik M, Marckmann G (2005) Persistent Vegetative State: Verhungern lassen oder sterben dürfen? Deutsches Ärzteblatt 102: A 2079-2082
77. Synofzik M (2006) Kognition a la carte? Der Wunsch nach kognitionsverbessernden Psychopharmaka in der Medizin. Zeitschrift für Ethik in der Medizin 18: 37-50
78. Synofzik M (2006) Wirksam, indiziert ? und dennoch ohne Nutzen? Die Ziele der medikamentösen Demenz-Behandlung und das Wohlergehen des Patienten. Z Gerontol Geriatr 39: 301-307
79. Taupitz J (2000) Die Situation des nicht äußerungsfähigen Patienten ohne (erreichbaren) Vertreter. In: Verhandlungen des 63. Juristentages Leipzig 2000, pp A36?51. Mücnhen: C.H. Beck
80. Van Rosendaal GM, Verhoef MJ, Kinsella TD (1999) How are decisions made about the use of percutaneous endoscopic gastrostomy for longterm nutritional support? Am J Gastroenterol 94: 3225-3228