Magnetic separation of micro-spheres from viscous biological fluids

Physics in Medicine and Biology

Volumn 52, Issue 4, 2007, Pages 1185-1196

  Chen, Haitao ^a,b   Kaminski, Michael D ^c   Caviness, Patricia L ^a,b   Liu, Xianqiao ^a   Dhar, Promila ^b   Torno, Michael ^a   Rosengart, Axel J ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b Illinois Institute of Technology   (United States)

^c ARGONNE NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD; MAGNETIC SEPARATION; MAGNETIZATION; MICROSPHERES; RADIOACTIVE ELEMENTS; VISCOSITY;

BIOHAZARDS; BLOOD FLOW; MAGNETIZABLE WIRES; VISCOUS BIOLOGICAL FLUIDS;

MAGNETIC FLUIDS;

ETHYLENE GLYCOL; FERROMAGNETIC MATERIAL; METAL; MICROSPHERE; NANOSPHERE; WATER; GLASS;

ARTICLE; BLOOD FLOW; FLUID FLOW; HUMAN; HYDRODYNAMICS; MAGNETIC FIELD; MAGNETIC SEPARATION; PRIORITY JOURNAL; VISCOSITY; BODY FLUID; CHEMISTRY; DRUG MIXTURE; ELECTROMAGNETIC FIELD; EQUIPMENT DESIGN; INSTRUMENTATION; ISOLATION AND PURIFICATION; MAGNETISM; METHODOLOGY; MICROFLUIDIC ANALYSIS; NANOTECHNOLOGY; RADIATION EXPOSURE;

BODY FLUIDS; COMPLEX MIXTURES; ELECTROMAGNETIC FIELDS; EQUIPMENT DESIGN; ETHYLENE GLYCOL; GLASS; HUMANS; MAGNETICS; METALS; MICROFLUIDIC ANALYTICAL TECHNIQUES; MICROSPHERES; NANOTECHNOLOGY; REGIONAL BLOOD FLOW; VISCOSITY; WATER;

EID: 34247105887     PISSN: 00319155     EISSN: 13616560     Source Type: Journal    
DOI: 10.1088/0031-9155/52/4/022     Document Type: Article

References (41)

1. Armed Forces Radiobiology Research Institute (AFRRI) 1999 Medical Management of Radiological Casualties Handbook (Bethesda, MD: AFRRI) p 34
2. Augusto P A, Augusto P and Castelo-Grande T 2004 Magnetic shielding: application to a new magnetic separator and classifier J. Magn. Magn. Mater. 272 2296-8
3. Badescu V, Rotariu O, Murariu V and Rezlescu N 1996 Numerical results and designing aspects concerning the HGMF filtering cells with bound flow field Int. J. Multiphase Flow 22 797-805
4. Carew B 1992 Method for separating pathogenic or toxic agents from a body fluid and return to body US Patent US5123901/1992
5. Chalmers J J, Zborowski M, Sun L P and Moore L 1998 Flow through, immunomagnetic cell separation Biotechnol. Prog. 14 141-8
6. Chen H, Ebner A D, Rosengart A J, Kaminski M D and Ritter J A 2005 Analysis of magnetic drug sphere particle capture by a magnetizable intravascular stent: II. Parametric study with multi-wire two-dimensional model J. Magn. Magn. Mater. 293 616-32
7. Chen H, Ebner A D, Ritter J A, Kaminski M D and Rosengart A J 2006a Magnetic separator device for ex-vivo blood detoxification: I. Theoretical analysis J. Appl. Phys. at press
8. Chen H, Ebner A D, Ritter J A, Kaminski M D and Rosengart A J 2006b Magnetic separator device for ex-vivo blood detoxification: II. In vitro investigation J. Appl. Phys. in preparation
9. Chien S 1976 Electrochemical interactions between erythrocyte surfaces Thromb. Res. 8 (suppl. 2) 189-202
10. Choi J, Ahn C H, Bhansali S and Henderson H T 2000 A new magnetic bead-based, filterless bio-separator with planar electromagnetic surfaces for integrated bio-detection systems Sensors Actuators B 68 34-9
11. Fahraeus R and Lindqvist T 1931 The viscosity of the blood in narrow capillary tubes Am. J. Physiol. 96 562-8
12. Furdui V I and Harrison D J 2004 Immunomagnetic T cell capture from blood for PCR analysis using microfluidic systems Lab Chip 4 614-8
13. Furlani E P 2006 Analysis of particle transport in a magnetophoretic microsystem J. Appl. Phys. 99 024912
14. Gordon L S 2003 Magnetic extracorporeal circuit for removal of medical agents US Patent US0120202/2003
15. Grano V, Diano N, Portaccio M, Bencivenga U, De Maio A, De Santo N, Perna A, Salamino F and Mita D G 2002 The alpha(1)-antitrypsin/elastase complex as an experimental model for hemodialysis in acute catabolic renal failure, extracorporeal blood circulation and cardiocirculatory bypass Int. J. Artif. Organs 25 297-305
16. Halikas G and Sheppard C W 1969 The viscosity of water and of blood in small diameter capillary tubes Biorheology 6 137-42
17. Han K H and Frazier A B 2004 Continuous magnetophoretic separation of blood cells in microdevice format J. Appl. Phys. 96 5797-802
18. Inglis D W, Riehn R, Austin R H and Sturm J C 2004 Continuous microfluidic immunomagnetic cell separation Appl. Phys. Lett. 85 5093-5
19. Karapinar N 2003 Magnetic separation of ferrihydrite from wastewater by magnetic seeding and high-gradient magnetic separation Int. J. Miner. Process. 71 45-54
20. Kiani M F and Hudetz A G 1991 A semiempirical model of apparent blood-viscosity as a function of vessel diameter and discharge hematocrit Biorheology 28 65-73
21. McCloskey K E, Moore L R, Hoyos M, Rodriguez A, Chalmers J J and Zborowski M 2003 Magnetophoretic cell sorting is a function of antibody binding capacity Biotechnol. Prog. 19 899-907
22. Miltenyi S, Mller W, Weichel W and Radbruch A 1990 High gradient magnetic cell separation with MACS Cytometry 11 231-8
23. Nakamura M, Decker K, Chosy J, Comella K, Melnik K, Moore L, Lasky L C, Zborowski M and Chalmers J J 2001 Separation of a breast cancer cell line from human blood using a quadrupole magnetic flow sorter Biotechnol. Prog. 17 1145-55
24. National Council on Radiation Protection and Measurements (NCRP) 1980 Management of persons accidentally contaminated with radionuclides NCRP Report 65 20
25. National Council on Radiation Protection and Measurements (NCRP) 2001 Management of terrorist events involving radioactive material NCRP Report 138 27
26. Nedelcu S and Watson J H P 2002 Magnetic separator with transversally magnetised disk permanent magnets Miner. Eng. 15 355-9
27. Pamme N and Manz A 2004 On-chip free-flow magnetophoresis: continuous flow separation of magnetic particles and agglomerates Anal. Chem. 76 7250-6
28. Pekas N, Granger M, Tondra M, Popple A and Porter M D 2005 Magnetic particle diverter in an integrated microfluidic format J. Magn. Magn. Mater. 293 584-8
29. Pries A R, Neuhaus D and Gaehtgens P 1992 Blood-viscosity in tube flow-dependence on diameter and hematocrit Am. J. Physiol. 263 H1770-8
30. Reinke W, Gaehtgens P and Johnson P C 1987 Blood-viscosity in small tubes-effect of shear rate, aggregation and sedimentation Am. J. Physiol. Heart Circ. Physiol. 253 H540-7
31. Ritter J A, Ebner A D, Daniel K D and Stewart K L 2004 Application of high gradient magnetic separation principles to magnetic drug targeting J. Magn. Magn. Mater. 280 184-201
32. Rosengart A J and Kaminaki M D 2005 Nanofabrication Towards Biomedical Applications ed S S S R Kumar, J Hormers and C Leuschner (Weinheim: Wiley-VCH)
33. Rotariu O, Ogden I D, Macrae M, Udrea L E and Strachan N J C 2005 Multiple sample flow through immunomagnetic separator for concentrating pathogenic bacteria Phys. Med. Biol. 50 2967-77
34. Senyei A, Widder K and Czerlinski G 1978 Magnetic guidance of drug-carrying microspheres J. Appl. Phys. 49 3578-83
35. Snabre P, Bitbol M and Mills P 1987 Cell disaggregation behavior in shear flow Biophys. J. 51 795-807
36. Swartz R D, Somermeyer M G and Hsu C H 1982 Preservation of plasma-volume during hemodialysis depends on dialysate osmolality Am. J. Nephrol. 2 189-94
37. Takayasu M, Kelland D R and Minervini J V 2000 Continuous magnetic separation of blood components from whole blood IEEE Trans. Appl. Supercond. 10 927-30
38. Tibbe A G J, de Grooth B G, Greve J, Dolan G J, Rao C and Terstappen L W M M 2002 Magnetic field design for selecting and aligning immunomagnetic labeled cells Cytometry 47 163-72
39. Wada Y, Yamamoto K, Tsukamoto O, Ohara T, Miyake C and Mori S 1994 Column and method for separating particles in accordance with their magnetic susceptibility US Patent US5465849/1994
40. Yang M C and Lin C C 2000 In vitro characterization of the occurrence of hemolysis during extracorporeal blood circulation using a mini hemodialyzer ASAIO J. 46 293-7
41. Zborowski M, Fuh C B, Green R, Sun L P and Chalmers J J 1995 Analytical magnetapheresis of ferritin-labeled lymphocytes Anal. Chem. 67 3702-12