Genetic strain differences in platelet aggregation and thrombus formation of laboratory rats

Thrombosis and Haemostasis

Volumn 97, Issue 4, 2007, Pages 665-672

  Sudo, Toshiki ^a   Ito, Hideki ^a   Hayashi, Hideki ^a   Nagamura, Yoshie ^a   Toga, Kazuyuki ^a   Yamada, Yoshihisa ^a  

^a OTSUKA PHARMACEUTICAL CO LTD   (Japan)

Author keywords

Difference; Platelet aggregation; Rat; Strain; Thrombus formation

Indexed keywords

ADENOSINE DIPHOSPHATE; COLLAGEN; FERRIC CHLORIDE; THROMBIN RECEPTOR ACTIVATING PEPTIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIOVENOUS SHUNT; ARTICLE; BLEEDING TIME; BROWN NORWAY RAT; CAROTID ARTERY THROMBOSIS; CONTROLLED STUDY; FISCHER 344 RAT; LEWIS RAT; NONHUMAN; PRIORITY JOURNAL; RAT; SPRAGUE DAWLEY RAT; STRAIN DIFFERENCE; THROMBOCYTE AGGREGATION; THROMBOGENESIS; THROMBOSIS; WISTAR RAT;

ADENOSINE DIPHOSPHATE; ANIMALS; ARTERIOVENOUS SHUNT, SURGICAL; BLEEDING TIME; BLOOD PLATELETS; COLLAGEN; DISEASE MODELS, ANIMAL; DRUG EVALUATION, PRECLINICAL; FERRIC COMPOUNDS; FIBRINOLYTIC AGENTS; PLATELET AGGREGATION; PLATELET AGGREGATION INHIBITORS; RATS; RATS, INBRED ACI; RATS, INBRED BN; RATS, INBRED F344; RATS, INBRED LEW; RATS, SPRAGUE-DAWLEY; RATS, WISTAR; RECEPTORS, THROMBIN; SPECIES SPECIFICITY; THROMBOSIS; VARIATION (GENETICS);

EID: 34247095674     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH06-05-0668     Document Type: Article

References (45)

1. Ruggeri ZM. Platelets in atherothrombosis. Nat Med 2002; 8: 1227-1234.
2. Jackson SP, Schoenwaeldcr SM. Antiplatelet therapy: in search of the 'magic bullef'. Nat Rev Drug Discov 2003; 2: 775-789.
3. Ni H, Denis CV, Subbarao S, et al. Persistence of platelet thrombus formation in arterioles of mice lacking both von Willebrand factor and fibrinogen. J Clin Invest 2000; 106: 385-392.
4. Yang H, Reheman A, Chen P, et al. Fibrinogen and von Willebrand factor-independent platelet aggregation in vitro and in vivo. J Thromb Haemost 2006; 4: 2230-2237.
5. Nieswandt B, Aktas B, Moers A, et al. Platelets in atherothrombosis: lessons from mouse models. J Thromb Haemost 2005; 3: 1725-1736.
6. Abott A. Laboratory animals: the renaissance rat. Nature 2004; 428: 464-466.
7. Kurz KD, Main BW, Sandusky GE. Rat model of arterial thrombosis induced by ferric chloride. Thromb Res 1990; 60: 269 280.
8. Dietrich WD, Watson BD, Busto R, et al. Photochemically induced cerebral infaction. I. Early microvascular alterations. Acta Neuropathol 1987; 72: 315-325.
9. Hladovec J. Experimental arterial thrombosis in rats with continuous registration. Thromb Diath Haemorrh 1971; 26: 407-410.
10. Umetsu T, Sanai K. Effect of 1-methyl-2-mercap-to-5-(3-pyridyl)-imidazole (KC-6141), an anti-aggregating compound, on experimental thrombosis in rats. Thromb Haemost 1978; 28: 74-83.
11. Lindsey JR. Historical foundations. In: The Laboratory Rat. Vol. 1. Biology and Diseases. Academic Press 1979; 2-36.
12. Okamoto K, Aoki K. Development of a strain of spontaneously hypertensive rats. Jpn Circ J 1963; 27: 282-293.
13. Okamoto K, Yamori Y, Nagaoka A. Establishment of the stroke-prone spontaneously hypertension rat (SHR). Circ Res 1974; 34/35 (Suppl): 143-153.
14. Kawano K, Hirashima T, Mori S, et al. Spontaneous long-term hyperglycemic rat with diabetic complications. Otsuka Long-Evans Tokushima Fatty (OLETF) strain. Diabetes 1992; 41: 1422-1428.
15. Harmon KJ, Couper LL, Lindner V Strain-dependent vascular remodeling phenotypes in inbred mice. Am J Pathol 2000; 156: 1741-1748.
16. Korshunov VA, Berk BC. Strain-dependent vascular remodeling: the "Glagov phenomenon" is genetically determined. Circulation 2004; 110: 220-226.
17. Kuhel DG, Zhu B, Witte DP, et al. Distinction in genetic determinants for injury-induced neointimal hyperplasia and diet-induced atherosclerosis in inbred mice. Arterioscler Thromb Vasc Biol 2002; 22: 955-960.
18. Sindermann JR, Kobbert C, Skaletz-Rorowski A, et al. Vascular injury response in mice is dependent on genetic background. Am J Physiol Heart Circ Physiol 2006; 290: H1307-1310.
19. Helisch A, Wagner S, Khan N, et al. Impact of mouse strain differences in innate hindlimb collateral vasculature. Arterioscler Thromb Vasc Biol 2006; 26: 520-526.
20. Assadnia S, Rapp JP, Nestor AL, et al. Strain differences in neointimal hyperplasia in the rat. Circ Res 1999; 84: 1252-1257.
21. Tanase H, Yamori Y, Hansen CT, et al. Heart size in inbred strains of rats. Part 1. Genetic determination of the development of cardiovascular enlargement in rats. Hypertension 1982; 4: 864-872.
22. Sudo T, Ito H, Kimura Y. Genetic strain differences in platelet aggregation of laboratory mice. Thromb Haemost 2006; 95: 159-165.
23. Li TT, Larrucea S, Souza S, et al. Genetic variation responsible for mouse strain differences in integrin α2 expression is associated with altered platelet responses to collagen. Blood 2004; 103: 3396-3402.
24. Ozeki Y, Sudo T, Toga K, et al. Characterization of whole blood aggregation with a new type of aggregometer by a screen filtration pressure method. Thromb Res 2001; 101: 65-72.
25. Sudo T, Ito H, Kimura Y. Characterization of platelet aggregation in whole blood of laboratory animals by a screen filtration pressure method. Platelets 2003; 14: 239-246.
26. Sudo T, Ito H, Ozeki Y, et al. Estimation of anti-platelet drugs on human platelet aggregation with a novel whole blood aggregometer by a screen filtration pressure method. Br J Pharmacol 2001; 133: 1396-1404.
27. Rat Genome Sequencing Project Consortium. Genome sequence of the Brown Norway rat yields insights into - mammalian evolution. Nature 2004; 428: 493-521.
28. Pravenec; M, Kunes J, Zicha J, et al. Platelet aggregation in spontaneous hypertension: genetic determination and correlation analysis. J Hypertens 1992; 10: 1453-1456.
29. Klinger MHE Inflamation. In: Platelets. San Diego: Academic Press, 2002: 459-467.
30. Tanaka S, Tamaya N, Matsuzawa K, et al. Differences in survivability among F344 rats. Exp Anim 2000; 49: 141-145.
31. Sonaka I, Futami Y, Kobayashi T, et al. Effects of dietary protein restriction on nitrogen balance and cardiovascular functions in aged rats. J Gerontol 1993; 48: B145-150.
32. 2+ mobilization and aggregatory response to ADP and thrombin in aged rat platelets. Platelets 1995; 6: 388-393.
33. Levy AE, Alexander JW. Administration of intragraft interleukin-4 prolongs cardiac allograft survival in rats treated with donor-specific transfusion/cyclosporine. Transplantation 1995; 60: 405-406.
34. Tchervenkov JI, Cofer BR, Davies C, et al. Indefinite allograft survival induced by the combination of multiple donor-specific transfusions, cyclosporine, and an anti-T cell monoclonal antibody in a protocol relevant to cadaveric organ transplantation. The importance of prolonged posttransplant cyclosporine coverage. Transplantation 1995; 59: 821-824.
35. Maffrand JP, Bernat A, Delebassee D, et al. ADP plays a key role in thrombogenesis in rats. Thromb Haemost 1988; 59: 225-230.
36. Sugidachi A, Asai F, Ogawa T, et al. The in vivo pharmacological profile of CS-747, a novel antiplatelet agent with platelet ADP receptor antagonist properties. Br J Pharmacol 2000; 129: 143 9-1446.
37. Freund M, Mantz F, Nicolini P et al. Experimental thrombosis on a collagen coated arterioarterial shunt in rats: a pharmacological model to study antithrombotic agents inhibiting thrombin formation and platelet deposition. Tbromb Haemost 1993; 69: 515-521.
38. Berry CN, Visconte C, Lecoffire C, et al. Activity of a sub-cutaneously administered novel mixed micellar formulation of argatroban in rat and rabbit models of venous thrombosis. Thromb Haemost 2000; 84: 286-290.
39. Cook NS, Zerwes H, Tapparelli C, et al. Platelet aggregation and fibrinogen binding in human, rhesus monkey, guinea-pig, hamster and rat blood: activation by ADP and a thrombin receptor peptide and inhibition by glycoprotein IIb/IIIa antagonists. Thromb Haemost 1993; 70: 531-539.
40. Kurata M, Ishizuka N, Matsuzawa M, et al. A comparative study of whole-blood platelet aggregation in laboratory animals: its species differences and comparison with turbidimetric method. Comp, Biochem Physiol 1995; 112C: 359 365.
41. Mattig S, Knoefler R, Deussen A. Modulation of adenine nucleotide concentrations in human plasma by erythrocytes and endothelial cells. Thromb Res 2003; 110: 195 202.
42. Heptinstall S, Johnson A, Glenn JR, et al. Adenine nucleotide metabolism in human blood - important roles for leukocytes and erythrocytes. J Thromb Haemost 2005; 3: 2331-2339.
43. Emms H, Lewis GP. The effect of ovarian hormones on an in vivo model of thrombosis in the rat. Br J Pharmacol 1985; 84: 243-248.
44. Emms H, Lewis GP. Sex and hormonal influences on platelet sensitivity and coagulation in the rat. Br J Pharmacol 1985; 86: 557-563.
45. Morikawa M, Kojima T, Inoue M, et al. Sex difference in the effect of aspirin on rat platelet aggregation and arachidonic acid metabolism. Jpn J Pharmacol 1985; 37: 317-323.