Treatment of extensive cutaneous metastatic melanoma with topical diphencyprone

Journal of the American Academy of Dermatology

Volumn 56, Issue 5, 2007, Pages 869-871

  Damian, Diona L ^a,b,c   Thompson, John F ^b,c  

^a Department of Dermatology ^*  (Australia)

^b Melanoma and Skin Cancer Research Institute   (Australia)

^c ROYAL PRINCE ALFRED HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

DIPHENCYPRONE;

AGED; ARTICLE; CANCER RADIOTHERAPY; CANCER REGRESSION; CANCER SURGERY; CASE REPORT; CLINICAL FEATURE; DRUG EFFECT; DRUG EFFICACY; DRUG TOLERABILITY; HUMAN; IMMUNOTHERAPY; MALE; MELANOMA; METASTASIS; PRIORITY JOURNAL; SYMPTOM;

ADMINISTRATION, TOPICAL; AGED; ANTINEOPLASTIC AGENTS; CYCLOPROPANES; HUMANS; MALE; MELANOMA; NEOPLASM RECURRENCE, LOCAL; SKIN NEOPLASMS;

EID: 34147214020     PISSN: 01909622     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaad.2006.12.018     Document Type: Article

References (14)

1. Hurwitz P.J. Spontaneous regression of metastatic melanoma. Ann Plast Surg 26 (1991) 403-406
2. Wack C., Kirst A., Becker J.C., KLutz W.K., Brocker E.B., and Fischer W.H. Chemoimmunotherapy for melanoma with dacarbazine and 2,4-dinitrochlorobenzene elicits a specific T cell-dependent immune response. Cancer Immunol Immunother 51 (2002) 431-439
3. Harland C.C., and Saihan E.M. Regression of cutaneous metastatic malignant melanoma with topical diphencyprone and oral cimetidine. Lancet 8660 (1989) 445
4. Trefzer U., and Sterry W. Topical immunotherapy with diphenylcyclopropenone in combination with DTIC and radiation for cutaneous metastases of melanoma. Dermatology 211 (2005) 370-371
5. Buckley D.A., and Du Vivier A.W.P. The therapeutic use of topical contact sensitizers in benign dermatoses. Br J Dermatol 145 (2001) 385-405
6. Malek-Mansour S. Remission of melanoma with D.N.C.B. treatment. Lancet 2 (1973) 503-504
7. Illig L., Paul E., and Bodeker R.I.I. Epifocal dinitrochlorobenzene therapy in malignant melanoma (experience during the last 8 years). Anticancer Res 4 (1984) 468-474
8. von Nida J., and Quirk C. Successful treatment of in-transit melanoma metastases using topical 2-4 dinitrochlorobenzene. Australas J Dermatol 44 (2003) 277-280
9. Wilkerson M.G., Connor T.H., and Wilkin J.K. Dinitrochlorobenzene is inherently mutagenic in the presence of trace mutagenic contaminants. Arch Dermatol 124 (1988) 396-398
10. DeLeve L.D. Dinitrochlorobenzene is genotoxic by sister chromatid exchange in human skin fibroblasts. Mutat Res 371 (1996) 105-108
11. Feldman R.J., and Maibach H.I. Absorption of some organic compounds through the skin in man. J Invest Dermatol 54 (1970) 399-404
12. Wolf P., Rieger E., and Kerl H. Topical photodynamic therapy with endogenous porphyrins after application of 5-aminolevulinic acid. J Am Acad Dermatol 28 (1993) 17-21
13. Steinman A., Funk J.O., Schuler G., and von den Driesch P. Topical imiquimod treatment of a cutaneous melanoma metastasis. J Am Acad Dermatol 43 (2000) 555-556
14. Hesling C., D'Incan M., Mansard S., Franck F., Corbin-Duval A., Chevenet C., et al. In vivo and in situ modulation of the expression of genes involved in metastasis and angiogenesis in a patient treated with topical imiquimod for melanoma skin metastases. Br J Dermatol 150 (2004) 761-767