Does coronary artery bypass surgery affect metoprolol bioavailability

European Journal of Clinical Pharmacology

Volumn 63, Issue 5, 2007, Pages 471-478

  Valtola, Antti ^a   Kokki, Hannu ^a,b   Gergov, Merja ^c   Ojanperä, Ilkka ^c   Ranta, Veli Pekka ^b   Hakala, Tapio ^d  

^a KUOPIO UNIVERSITY HOSPITAL   (Finland)

^b UNIVERSITY OF EASTERN FINLAND   (Finland)

^c UNIVERSITY OF HELSINKI   (Finland)

^d NORTH KARELIA CENTRAL HOSPITAL   (Finland)

Author keywords

Administration; Area Under Curve; Atrial fibrillation; Coronary artery bypass grafting surgery; Drug administration routes; Metoprolol; Oral; Pharmacokinetics

Indexed keywords

METOPROLIN; METOPROLOL TARTRATE; UNCLASSIFIED DRUG;

ADULT; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; CLINICAL ARTICLE; CLINICAL TRIAL; CONCENTRATION RESPONSE; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORONARY ARTERY BYPASS SURGERY; CORRELATION COEFFICIENT; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; HEART ATRIUM FIBRILLATION; HUMAN; LIQUID CHROMATOGRAPHY; MALE; OUTCOME ASSESSMENT; PATIENT INFORMATION; POSTOPERATIVE CARE; PREOPERATIVE PERIOD; PRIORITY JOURNAL; STATISTICAL ANALYSIS; TANDEM MASS SPECTROMETRY;

ADMINISTRATION, ORAL; ADRENERGIC BETA-ANTAGONISTS; AREA UNDER CURVE; ATRIAL FIBRILLATION; BIOLOGICAL AVAILABILITY; CHROMATOGRAPHY, LIQUID; CORONARY ARTERY BYPASS; HUMANS; INTESTINAL ABSORPTION; MALE; METOPROLOL; MIDDLE AGED; POSTOPERATIVE COMPLICATIONS; TANDEM MASS SPECTROMETRY;

EID: 34147212419     PISSN: 00316970     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00228-007-0276-6     Document Type: Article

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