Separation of ibuprofen enantiomers by chiral extraction with hydrophobic tartaric esters

Huagong Xuebao/Journal of Chemical Industry and Engineering (China)

Volumn 58, Issue 3, 2007, Pages 679-684

  Yan, Jianhui ^a,b   Sheng, Ying ^a,b   Huang, Kelong ^b   Tang, Kewen ^a   Yi, Jianmin ^a  

^a HUNAN INSTITUTE OF SCIENCE AND TECHNOLOGY   (China)

^b CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

Chiral extraction; D tartaric esters; Ibuprofen; L tartaric esters

Indexed keywords

ALCOHOLS; CHIRALITY; ESTERS; METHANOL; ORGANIC SOLVENTS; PARAFFINS; SOLVENT EXTRACTION;

CHIRAL EXTRACTION; D-TARTARIC ESTERS; IBUPROFEN; L-TARTARIC ESTERS;

ENANTIOMERS;

EID: 34147193148     PISSN: 04381157     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Dai Zhen, Wang Dahui. The summarization of research and preparation of chiral pharmaceutical. Pharmic and Clinical Research in Jiangsu, 2003, 11(5): 24-27
2. Tang Kewen, Zhou Chunshan. Separation of chlorothalidone enantiomers by chiral extraction with lipophilic L-tartaric esters. Chinese Journal of Analytical Chemistry, 2004, 32(1): 63-66
3. Cen Zhezhong, Cai Shuihong. Solvent extraction of ephedrine epimerides with chiral agents. Journal of Chemical Industry and Engineering (China), 2002, 51(3): 418-420
4. Xiang Yanlong, Cai Shuihong. The rearch of resolution of racemic acid with amine solvent from liquid. Chemistry Magazine, 2000, 9: 53-56
5. Tang Kewen, Zhou Chunshan. Enantionselective separation of racemicmandelic acid by chiral extraction with lipophilic X-tartiaric esters. Applied Chemistry, 2003, 20(11): 1108-1110
6. Tang Kewen, Zhou Chunshan, Jiang Xinyu. Racemic ofloxacin separation by supported-liquid membrane extraction with two organic phases. Science China (Series B), 2003, 46(1): 491-496
7. Tang Kewen, Zhou Chunshan, Yi Jianmin, Zhang Weizhen. Enantioselective separation of ofloxacin enantiomers by chiral ligand exchange. Acta Chemica Sinica, 2004, 62(17): 1621-1625
8. Tang Kewen, Zhou Chunshan. Chiral solvent extraction of terbutaline enatiomers by lipophilic phase transfer. Chinese Journal of Analytical Chemistry, 2004, 32(3): 278-282
9. Tang Kewen, Zhou Chunshan. Extraction of ofloxacin enantiomers with lipophilic L-tartiaric esters. Journal of Chemical Industry and Engineering (China), 2003, 54(2): 1729-1732
10. Toshifumi T T, Rikizo H, Takenori T. Enantioselective solvent extraction of neutral DL-amino acids in two-phase systems containing N-n-alkyl-L-proline derivative and copper (II) ion. Anal. Chem., 1984, 56: 1152-1155
11. Li Chengping. High performance liquid chromatographic separation of drug enantiomer using chiral mobile phase additives[D]. Hangzhou: Zhejiang University of Technology, 2003
12. Chen Guobin, Tang Kewen, Chen Tiehua, Zhu Zhengbing. Synthesis of L-tartrate-n-hexyl. Chinese Journal of Synthetic Chemistry, 2004, 12(3): 207-209
13. Chen Guobin, Tang Kewen, Chen Tiehua, Zhu Zhengbing. Synthesis of hydrophobic L-dipentyl tartrate. Fine Chemicals, 2004, 21(10): 738-740
14. You Tianba. Morden Research Measures of Chiral Compoud. Hefei: University of Science and Technology of China Press, 1993: 85-90