Molecular typing and antifungal susceptibility of Trichophyton rubrum isolates from patients with onychomycosis pre- and post-treatment

International Journal of Antimicrobial Agents

Volumn 29, Issue 5, 2007, Pages 563-569

  de Assis Santos, Daniel ^a   de Carvalho Araújo, Roberta Amália ^a   Kohler, Lidiane Meire ^a   Machado Pinto, Jackson ^b   Hamdan, Júnia Soares ^a   Cisalpino, Patrícia Silva ^a  

^a FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^b Acad mica de Medicina   (Brazil)

Author keywords

Drug susceptibility; Onychomycosis; Strain typing; Trichophyton rubrum

Indexed keywords

CICLOPIROXOLAMINE; CLOTRIMAZOLE; FLUCONAZOLE; GRISEOFULVIN; ISOCONAZOLE; ITRACONAZOLE; KETOCONAZOLE; MICONAZOLE; TERBINAFINE;

ANTIFUNGAL ACTIVITY; ARTICLE; DILUTION; DRUG POTENCY; DRUG SENSITIVITY; FUNGAL STRAIN; FUNGUS ISOLATION; GENOTYPE; HUMAN; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR TYPING; NONHUMAN; ONYCHOMYCOSIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; TANDEM REPEAT; TRICHOPHYTON RUBRUM;

ANTIFUNGAL AGENTS; CHILD, PRESCHOOL; DNA, FUNGAL; HUMANS; INFANT; MICROBIAL SENSITIVITY TESTS; ONYCHOMYCOSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRICHOPHYTON;

EID: 34147190490     PISSN: 09248579     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijantimicag.2006.09.028     Document Type: Article

References (24)

1. Shin J.H., Sung J.H., Park S.J., et al. Species identification and strain differentiation of dermatophyte fungi using polymerase chain reaction amplification and restriction enzyme analysis. J Am Acad Dermatol 48 (2003) 857-865
2. Yazdanparast A., Jackson C.J., Barton R.C., and Evans E.G.V. Molecular strain typing of Trichophyton rubrum indicates multiple strain involvement in onychomycosis. Br J Dermatol 148 (2003) 51-54
3. Cordeiro R.A., Brilhante R.S.N., Rocha M.F.G., et al. Antifungal susceptibility and genetic similarity of sequential isolates of Trichophyton rubrum from an immunocompetent patient with chronic dermatophytosis. Clin Exp Dermatol 31 (2005) 122-124
4. Scher R.K., and Baran R. Onychomycosis in clinical practice: factors contributing to recurrence. Br J Dermatol 149 (2003) 5-9
5. Baeza L.C., and Mendes-Giannini M.J.S. Strain differentiation of Trichophyton rubrum by random amplification of polymorphic DNA (RAPD). Rev Inst Med Trop Sao Paulo 46 (2004) 339-341
6. Jackson C.K., Barton R.C., Kelly S.L., and Evans E.G.V. Strain identification of Trichophyton rubrum by specific amplification of subrepeat elements in the ribosomal DNA nontranscribed spacer. J Clin Microbiol 38 (2000) 4527-4534
7. Jackson C.K., Barton R.C., and Evans E.G.V. Species identification and strain differentiation of dermatophyte fungi by analysis of ribosomal-DNA intergenic spacer regions. J Clin Microbiol 37 (1999) 931-936
8. Gupta A.K., and Kohli Y. In vitro susceptibility testing ciclopirox, terbinafine, ketoconazole and itraconazole against dermatophytes and nondermatophytes, and in vitro evaluation of combination antifungal activity. Br J Dermatol 149 (2003) 296-305
9. Mukherjee P.K., Leidich S.D., Isham N., et al. Clinical Trichophyton rubrum strain exhibiting primary resistance to terbinafine. Antimicrob Agents Chemother 47 (2003) 82-86
10. Santos D.A., Barros M.E.S., and Hamdan J.S. Establishing a method of inoculum preparation for susceptibility testing of Trichophyton rubrum and Trichophyton mentagrophytes. J Clin Microbiol 44 (2006) 98-101
11. Santos D.A., and Hamdan J.S. In vitro antifungal oral drug and drug combination activity against onychomycosis causative dermatophytes. Med Mycol 44 (2006) 357-362
12. Santos D.A., and Hamdan J.S. Evaluation of broth microdilution antifungal susceptibility testing conditions for Trichophyton rubrum. J Clin Microbiol 43 (2005) 1917-1920
13. Clinical and Laboratory Standards Institute (CLSI). Reference method for broth dilution antifungal susceptibility testing of filamentous fungi. Aproved standard M38-A. Clinical and Laboratory Standards Institute, Wayne, PA; 2002.
14. Barry A.L., Pfaller M.A., Brown S.D., et al. Quality control limits of broth microdilution susceptibility tests of ten antifungal agents. J Clin Microbiol 38 (2000) 3457-3459
15. Evans E.G.V., and Sigurgeirsson B. A double-blind randomized study of continuous terbinafine compared with intermittent for the treatment of toenail onychomycosis (LION Study). Br Med J 318 (1999) 1031-1035
16. Baeza L.C., Matsumoto M.T., Almeida A.M.F., and Mendes-Giannini M.J.S. Strain differentiation of Trichophyton rubrum by randomly amplified polymorphic DNA and analysis of rDNA nontranscribed spacer. J Med Microbiol 55 (2006) 429-436
17. Mochizuki T., Ishizaki H., Barton R.C., et al. Restriction fragment length polymorphism analysis of ribosomal DNA intergenic regions is useful for differentiating strains of Trichophyton mentagrophytes. J Clin Microbiol 41 (2003) 4583-4588
18. Gupta A.K., Kohli Y., and Summerbell R.C. Variation in restriction fragment length polymorphisms among serial isolates from patients with Trichophyton rubrum infection. J Clin Microbiol 39 (2001) 3260-3266
19. Nir-Paz R., Elinav H., Pierard G.E., et al. Deep infection by Trichophyton rubrum in an immunocompromised patient. J Clin Microbiol 41 (2003) 5298-5301
20. Evans E.G.V. Drug synergies and the potential for combination therapy in onychomycosis. Br J Dermatol 149 (2003) 11-13
21. Olafsson J.H., Sigurgeirsson B., and Baran R. Combination therapy for onychomycosis. Br J Dermatol 149 (2003) 15-18
22. Gupta A.K., and Kohli Y. Evaluation of in vitro resistance in patients with onychomycosis who fail antifungal therapy. Dermatol 207 (2003) 375-380
23. Korting H.C., Ollert M., Abeck D., et al. Results of German multicenter study of antimicrobial susceptibilities of Trichophyton rubrum and Trichophyton mentagrophytes strains causing tinea unguium. Antimicrob Agents Chemother 39 (1995) 1206-1208
24. Cervelatti E.F., Fachin A.L., Ferreira-Nozawa M.S., and Martinez-Rossi N.M. Molecular cloning and characterization of a novel ABC transporter gene in the human pathogen Trichophyton rubrum. Med Mycol 44 (2006) 141-147