α-substituted 1-aryl-3-dimethylaminopropanone hydrochlorides: Potent cytotoxins towards human WiDr colon cancer cells

Chemical and Pharmaceutical Bulletin

Volumn 55, Issue 4, 2007, Pages 511-515

  Pati, Hari Narayan ^a   Das, Umashankar ^a   Ramirez Erosa, Irving Javier ^b   Dunlop, Donna Mae ^b   Hickie, Robert Allan ^b   Dimmock, Jonathan Richard ^a  

^a UNIVERSITY OF SASKATCHEWAN   (Canada)

^b UNIVERSITY OF SASKATCHEWAN   (Canada)

Author keywords

1 aryl 3 dimethylaminopropanone; Colon cancer; Cytotoxicity; Stability study

Indexed keywords

1 ARYL 2 DIMETHYLAMINOMETHYL 2 PROPENONE HYDROCHLORIDE DERIVATIVE; 1 ARYL 2 DIMETHYLAMINOMETHYL 3 HYDROXYPROPANONE HYDROCHLORIDE DERIVATIVE; 2 DIMETHYLAMINOMETHYL 1 (4 NITROPHENYL) 2 PROPENONE HYDROCHLORIDE 1C; 2 DIMETHYLAMINOMETHYL 3 (HYDROXYETHYLTHIO) 1 (4 NITROPHENYL) 1 PROPANONE HYDROCHLORIDE; 2 HYDROXYMETHYL 1 (4 NITROPHENYL) PROP 2 EN 1 ONE; CHLORIDE; CISPLATIN; DEUTERIUM OXIDE; DIMETHYLAMINE; UNCLASSIFIED DRUG; WATER;

ARTICLE; CANCER CELL; COLON CANCER; CYTOTOXICITY; DEAMINATION; DRUG MECHANISM; DRUG POTENCY; DRUG STABILITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; HYDRATION; IC 50;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; COLONIC NEOPLASMS; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; PROPIONIC ACIDS;

EID: 34147175924     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.55.511     Document Type: Article

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