A limited role for p21Cip1/Waf1 in maintaining normal hematopoietic stem cell functioning

Stem Cells

Volumn 25, Issue 4, 2007, Pages 836-843

  Van Os, Ronald ^a,b   Kamminga, Leonie M ^a   Ausema, Albertina ^a   Bystrykh, Leonid V ^a   Draijer, Deanna P ^a   Van Pelt, Kyrjon ^b   Dontje, Bert ^a   De Haan, Gerald ^a  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

^b UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

Aging; Cobblestone area forming cells; Competitive repopulation; Hematopoietic stem cells; P21; Stem cell exhaustion

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 1; CDKN1A PROTEIN, MOUSE; CYCLIN DEPENDENT KINASE INHIBITOR 1A; FLUOROURACIL; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BONE MARROW CELL; CELL COUNT; CELL CYCLE; CELL FUNCTION; CELL POPULATION; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; GENE EXPRESSION; HEMATOPOIETIC STEM CELL; IN VITRO STUDY; IN VIVO STUDY; IRRADIATION; MOUSE; NONHUMAN; ANIMAL; C57BL MOUSE; CELL DIVISION; CROSS BREEDING; CYTOLOGY; DRUG EFFECT; EMBRYO; FIBROBLAST; FLOW CYTOMETRY; GENETICS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; METHODOLOGY; MOUSE MUTANT; MOUSE STRAIN; PHYSIOLOGY; RADIATION EXPOSURE;

MUS;

ANIMALS; BONE MARROW CELLS; CELL COUNT; CELL CYCLE; CELL DIVISION; CROSSES, GENETIC; CYCLIN-DEPENDENT KINASE INHIBITOR P21; EMBRYO; FIBROBLASTS; FLOW CYTOMETRY; FLUOROURACIL; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEMATOPOIETIC STEM CELLS; MICE; MICE, INBRED C57BL; MICE, INBRED STRAINS; MICE, KNOCKOUT;

EID: 34147168247     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1634/stemcells.2006-0631     Document Type: Article

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