Do Langerhans cells play a role in vulvar epithelium resistance to squamous cell carcinoma?

Archivum Immunologiae et Therapiae Experimentalis

Volumn 55, Issue 2, 2007, Pages 127-130

  Rotsztejn, Helena ^a   Trznadel Budźko, Ewa ^b   Jesionek Kupnicka, Dorota ^b  

^a POLISH MOTHER S MEMORIAL HOSPITAL RESEARCH INSTITUTE   (Poland)

^b MEDICAL UNIVERSITY OF LODZ   (Poland)

Author keywords

Langerhans cells; Squamous cell carcinoma; Vulva

Indexed keywords

CD1 ANTIGEN; FORMALDEHYDE; PARAFFIN;

ADULT; AGED; ARTICLE; CARCINOGENESIS; CELL COUNT; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; IMMUNE SYSTEM; IMMUNOHISTOCHEMISTRY; LANGERHANS CELL; MEDICAL RESEARCH; SKIN BIOPSY; SKIN CARCINOMA; SQUAMOUS CELL CARCINOMA; STAINING; TISSUE SECTION; VULVA; VULVA DISEASE;

AGED; CARCINOMA, SQUAMOUS CELL; CASE-CONTROL STUDIES; EPITHELIUM; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; LANGERHANS CELLS; MIDDLE AGED; VULVAR NEOPLASMS;

EID: 34147165603     PISSN: 0004069X     EISSN: 16614917     Source Type: Journal    
DOI: 10.1007/s00005-007-0016-8     Document Type: Article

References (25)

1. Alcalay J., Goldberg L. H., Wolf J. E. Jr. and Kripke M. L. (1989): Variations in the number and morphology of Langerhans' cells in the epidermal component of squamous cell carcinomas. Arch. Dermatol., 125, 917-920.
2. Asadullah K., Docke W. D., Sabat R., Ebeling W., Volk H. D. and Sterry W. (1999): Interleukin-10 in der Dermatologie. Hautartzt, 50, 12-19.
3. Carlson J. A., Ambros R., Malfetano J., Ross J., Grabowski R., Lamb P., Figge H. and Mihm M. C. Jr. (1998): Vulvar lichen sclerosus and squamous cell carcinoma: a cohort, case control, and investigational study with historical perspective; implications for chronic inflammation and sclerosis in the development of neoplasia. Hum. Pathol., 29, 932-948.
4. Chaiyarit P., Ma N., Hiraku Y., Pinlaor S., Yongvanit P., Jintakanon P., Murata M., Oikawa S. and Kawanish S. (2005): Nitrative and oxidative DNA damage in oral lichen planus in relation to human oral carcinogenesis. Cancer Sci., 96, 553-559.
5. Crowe S. E. (2005): Helicobacter infection, chronic inflammation, and the development of malignancy. Curr. Opin. Gastroenterol., 21, 32-38.
6. Duan H., Koga T., Masuda T., Mashino T., Imafuku S., Terao H., Murakami Y., Urabe K., Kiryu H. and Furue M. (2000): CD1a+, CD3+, CD4+, CD8+, CD68+ and cutaneous lymphocyte-associated antigen-positive cells in Bowen's disease. Br. J. Dermatol., 143, 1211-1216.
7. Farrow B. and Evers B. M. (2002): Inflammation and the development of pancreatic cancer. Surg. Oncol., 10, 153-169.
8. Fernandez-Bussy R., Cambazard F., Mauduit G. Schmitt D. and Thivolet J. (1983): T cell subsets and Langerhans cells in skin tumours. Eur. J. Cancer Clin. Oncol., 19, 907-913.
9. Fox H. and Wells M. (2003): Recent advances in the pathology of the vulva. Histopathology, 43, 209-216.
10. Galvao M. M., Sotto M. N., Kihara S. M. Rivitti E. A. and Sabbaga E. (1998): Lymphocyte subsets and Langerhans cells in sun-protected and sun exposed skin of immuno-suppressed renal allograft recipients. J. Am. Acad. Dermatol., 38, 38-44.
11. Halliday G. M. and Le S. (2001): Transforming growth factor-beta produced by progressor tumors inhibits, while IL-10 produced by regressor tumors enhances, Langerhans cell migration from skin. Int. Immunol., 13, 1147-1154.
12. Itzkowitz S. H. and Yio X. (2004): Inflammation and cancer IV. Colorectal cancer in inflammatory bowel disease: the role of inflammation. Am. J. Physiol. Gastrointest. Liver Physiol., 287, G7-17.
13. Kurihara K. and Hashimoto N. (1985): The pathological significance of Langerhans cells oral cancer. J. Oral Pathol., 14, 289-298.
14. Meunier L. (1996): Immune dendritic cells in human dermis. Eur. J. Dermatol., 6, 327-331.
15. Meunier L. (1999): Ultraviolet light and dendritic cells. Eur. J. Dermatol., 9, 269-275.
16. Nakagawa S. and Bost J. D. (2001): Role of Langerhans cells in the skin. What's new? J. Eur. Acad. Dermatol. Venerol., 15, 399-401.
17. Poulsen H., Junge J., Vyberg M., Horn T. and Lundvall F. (2003): Small vulvar squamous cell carcinomas and adjacent tissues. A morphologic study. APMIS, 111, 835-842.
18. Riethdorf S., Neffen E. F., Cviko A., Loning T., Crum C. P. and Riethdorf L. (2004): p16INK4A expression as biomarker for HPV 16-related vulvar neoplasia. Hum. Pathol., 35, 1477-1483.
19. Rouzier R., Morice P., Haie-Meder C., Lhomme C., Avril M. F., Duvillard P. and Castaigne D. (2001): Prognostic significance of epithelial disorders adjacent to invasive vulvar carcinomas. Gynecol. Oncol., 81, 414-419.
20. Sander C. S., Ali I., Dean D., Thiele J. J. and Wojnarowska F. (2004): Oxidative stress is implicated in the pathogenesis of lichen sclerosus. Br. J. Dermatol., 151, 627-635.
21. Scurry J. P. and Vanin K. (1997): Vulvar squamous cell carcinoma and lichen sclerosus. Australas. J. Dermatol., 38 (suppl. 1), 20-25.
22. Seite S., Zucchi H., Moyal D., Tison S., Compan D., Christiaens F., Gueniche A. and Fourtanier A. (2003): Alterations in human epidermal Langerhans cells by ultraviolet radiation: quantitative and morphological study. Br. J. Dermatol., 148, 291-299.
23. Tiplica G. S. (2001): Dermatocorticoterapie. Curtea Veche, Bukaresti, 20-21.
24. Townsend W. L., Gorrell M. D. and Mayer R. (1997): Langerhans cells in the development of skin cancer: a qualitative and quantitative comparison of cell markers in normal, acanthotic and neoplastic ovine skin. Pathology, 29, 42-50.
25. Weiss G. N., Sanders M. and Westbrook K. C. (1993): The distribution and density of langerhans cells in the human prepuce: site of a diminished immune response? Isr. J. Med. Sci., 29, 42-43.