Evaluation of in vitro enzymatic degradation of various thiomers and cross-linked thiomers

Drug Development and Industrial Pharmacy

Volumn 33, Issue 2, 2007, Pages 199-208

  Kafedjiiski, Krum ^a   Föger, Florian ^a   Hoyer, Herbert ^a   Bernkop Schnürch, Andreas ^a   Werle, Martin ^b  

^a UNIVERSITY OF INNSBRUCK   (Austria)

^b Thiomatrix Forschungs und Beratungs GmbH   (Austria)

Author keywords

Alginate lyase; Cellulase; Enzymatic degradation; Lysozyme; Thiolated alginates; Thiolated carboxymethylcelluloses; Thiolated chitosans; Thiomers; Viscosity measurements

Indexed keywords

ALGINATE CYSTEINE CONJUGATE; ALGINIC ACID; CARBOXYMETHYLCELLULOSE; CARBOXYMETHYLCELLULOSE CYSTEAMINE CONJUGATE; CARBOXYMETHYLCELLULOSE CYSTEINE CONJUGATE; CHITOSAN 4 THIOBUTYLAMIDINE CONJUGATE; CHITOSAN DERIVATIVE; CHITOSAN GLUTATHIONE CONJUGATE; CHITOSAN THIOETHYLAMIDINE; CHITOSAN THIOGLYCOLIC ACID CONJUGATE; DISULFIDE; POLYMER; THIOL GROUP; UNCLASSIFIED DRUG;

ARTICLE; BIODEGRADABILITY; CROSS LINKING; DISULFIDE BOND; DRUG DELIVERY SYSTEM; DRUG STABILITY; ENZYMATIC DEGRADATION; HYDROLYSIS; IN VITRO STUDY; OXIDATION; PH; ROOM TEMPERATURE; SPECTROPHOTOMETRY; TISSUE ENGINEERING; VISCOSITY;

ALGINATES; CARBOXYMETHYLCELLULOSE; CELLULASE; CHITOSAN; CROSS-LINKING REAGENTS; DISULFIDES; ENZYME ACTIVATION; ENZYMES; GLUTATHIONE; HYDROGEN-ION CONCENTRATION; HYDROLYSIS; MOLECULAR STRUCTURE; MURAMIDASE; POLYMERS; POLYSACCHARIDE-LYASES; PROTEIN DENATURATION; REPRODUCIBILITY OF RESULTS; SULFHYDRYL COMPOUNDS; TECHNOLOGY, PHARMACEUTICAL; VISCOSITY;

EID: 34147152760     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.1080/03639040600762651     Document Type: Article

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