Conjugated linoleic acid versus high-oleic acid sunflower oil: Effects on energy metabolism, glucose tolerance, blood lipids, appetite and body composition in regularly exercising individuals

British Journal of Nutrition

Volumn 97, Issue 5, 2007, Pages 1001-1011

  Lambert, Estelle V ^a   Goedecke, Julia H ^a   Bluett, Kerry ^a   Heggie, Kerry ^a   Claassen, Amanda ^a   Rae, Dale E ^a   West, Sacha ^a   Dugas, Jonathan ^a   Dugas, Lara ^a   Meltzer, Shelly ^a   Charlton, Karen ^a   Mohede, Inge ^b  

^a UNIVERSITY OF CAPE TOWN   (South Africa)

^b Loders Croklaan Lipid Nutrition ^*  (Netherlands)

Author keywords

Body fat distribution; CLA isomers; Exercise metabolism; Insulin sensitivity

Indexed keywords

CLARINOL; CONJUGATED LINOLEIC ACID; FATTY ACID; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; LINOLEIC ACID; LOW DENSITY LIPOPROTEIN CHOLESTEROL; OLEIC ACID; PALMITIC ACID; STEARIC ACID; SUNFLOWER OIL; UNCLASSIFIED DRUG;

ADULT; APPETITE; ARTICLE; BLOATING; BODY COMPOSITION; BODY WEIGHT; CHOLESTEROL BLOOD LEVEL; CLINICAL TRIAL; COMMON COLD; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIARRHEA; DIET SUPPLEMENTATION; DOUBLE BLIND PROCEDURE; DRUG INDUCED HEADACHE; DUAL ENERGY X RAY ABSORPTIOMETRY; ENERGY METABOLISM; EXERCISE; FATTY ACID BLOOD LEVEL; FEMALE; FLATULENCE; FOOD INTAKE; GLUCOSE TOLERANCE; GLUCOSE TOLERANCE TEST; HUMAN; HUMAN EXPERIMENT; INFLUENZA; INSULIN BLOOD LEVEL; INSULIN SENSITIVITY; LIPID ANALYSIS; MALE; METABOLIC RATE; NORMAL HUMAN; PATIENT COMPLIANCE; RANDOMIZED CONTROLLED TRIAL; SKIN IRRITATION;

ADULT; APPETITE; BODY COMPOSITION; CHOLESTEROL; DIETARY FATS, UNSATURATED; DIETARY SUPPLEMENTS; DOUBLE-BLIND METHOD; ENERGY INTAKE; ENERGY METABOLISM; EXERCISE; FEMALE; GLUCOSE TOLERANCE TEST; HUMANS; INSULIN; LINOLEIC ACIDS, CONJUGATED; MALE; MIDDLE AGED; OLEIC ACID; PATIENT COMPLIANCE; PLANT OILS; REST; TRIGLYCERIDES;

HELIANTHUS;

EID: 34147142577     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1017/S0007114507172822     Document Type: Article

References (29)

1. Benito P, Nelson GJ, Kelley DS, Bartolini G, Schmidt PC & Simon V (2001) The effect of conjugated linoleic acid on plasma lipoproteins and tissue fatty acid composition in humans. Lipids 36, 229-236.
2. Blair SN, Haskell WL, Ho P, Paffenbarger RS Jr, Vranizan KM, Farquhar JW & Wood PD (1985) Assessment of habitual physical activity by a seven-day recall in a community survey and controlled experiments. Am J Epidemiol 122, 794-804.
3. Blankson H, Stakkestad JA, Fargertun H, Thom E, Wadstein J & Gudmundsen O (2000) Conjugated linoleic acid reduces body fat mass in overweight and obese humans. J Nutr 130, 2943-2948.
4. Eyjolfson V, Spriet LL & Dyck DJ (2004) Conjugated linoleic acid improves insulin sensitivity in young, sedentary humans. Med Sci Sports Exerc 36, 814-820.
5. Flint A, Raben A, Blundell JE & Astrup A (2000) Reproducibility, power and validity of visual analogue scales in assessment of appetite sensations in single test meal studies. Int J Obes Relat Metab Disord 24, 38-48.
6. Frayn KN (1983) Calculation of substrate oxidation rates in vivo from gaseous exchange. J Appl Physiol 55, 628-634.
7. Friedewald WT, Levy RI & Fredrickson DS (1972) Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 18, 499-502.
8. 2max and performance time in trained cyclists. Eur J Appl Physiol Occup Physiol 65, 79-83.
9. Houseknecht KL, Vanden Heuvel JP, Moya-Camarena SY, Portocarrero CP, Peck LW, Nickel KP & Belury MA (1998) Dietary conjugated linoleic acid normalizes impaired glucose tolerance in the Zucker diabetic fatty fa/fa rat. Biochem Biophys Res Commun 244, 678-682.
10. Kamphuis MM, Lejeune MP, Saris WH & Westerterp-Plantenga MS (2003a The effect of conjugated linoleic acid supplementation after weight loss on body weight regain, body composition, and resting metabolic rate in overweight subjects. Int J Obes Relat Metab Disord 27, 840-847.
11. Kamphius MMJW, Lejeune MPGM, Saris WHM & Westerterp-Plantenga MS (2003 b) The effect of conjugated linoleic acid supplementation after weight loss on appetite and food intake in overweight subjects. Eur J Clin Nutr 57, 1268-1274.
12. Matsuda M & DeFronzo RA (1999) Insulin sensitivity indices obtained from oral glucose tolerance testing: Comparison with the euglycaemic insulin clamp. Diab Care 22, 1462-1470.
13. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF & Turner RC (1985) Homeostasis model assessment: Insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28, 412-419.
14. Medina EA, Horn WF, Keim NL, Havel PJ, Benito P, Kelley D, Nelson GJ & Erickson KL (2000) Conjugated linoleic acid supplementation in humans: effects on circulating leptin concentrations and appetite. Lipids 35, 783-788.
15. Moloney F, Yeow T, Mullen A, Nolan JJ & Roche HM (2004) Conjugated linoleic acid supplementation: Insulin sensitivity, and lipoprotein metabolism in patients with type 2 diabetes mellitus. Am J Clin Nutr 80, 887-895.
16. Noone EJ, Roche HM, Nugent AP & Gibney MJ (2002) The effect of dietary supplementation using isomeric blends of conjugated linoleic acid on lipid metabolism in healthy human subjects. Br J Nutr 88, 243-251.
17. Perseghin G, Caumo A, Caloni M. Testolin G & Luzi L (2001) Incorporation of the fasting plasma FFA concentration into QUICKI improves its association with insulin sensitivity in non-obese individuals. J Clin Endocrinol Metab 86, 4776-4781.
18. Phillips DIW, Clark PM, Hales CN & Osmond C (1994) Understanding oral glucose tolerance: Comparison of glucose or insulin measurements during the oral glucose tolerance test with specific measurements of insulin resistance and insulin secretion. Diab Med 11, 286-292.
19. Rahman SM, Wang Y, Yotsumoto H, Cha J, Han S. Inoue S & Yanagita T (2001) Effects of conjugated linoleic acid on serum leptin concentration, body-fat accumulation, and β-oxidation of fatty acid in OLEFT rats. Nutrition 17, 385-390.
20. Risérus U, Arner P, Brismar K & Vessby B (2002) Treatment with dietary trans 10 cis12 conjugated linoleic acid causes isomerspecific insulin resistance in obese men with the metabolic syndrome. Diabet Care 25, 1516-1521.
21. Risérus U, Berglund L & Vessby B (2001) Conjugated linoleic acid (CLA) reduced abdominal adipose tissue in obese middle-aged men with signs of the metabolic syndrome: A randomised controlled trial. Int J Obes Relat Metab Disord 25, 1129-1135.
22. Risérus U, Vessby B, Arnlov J & Basu S (2004a) Effects of cis-9,trans-11 conjugated linoleic acid supplementation on insulin sensitivity, lipid peroxidation, and proinflammatory markers in obese men. Am J Clin Nutr 80, 279-283.
23. Risérus U, Vessby B, Arner P & Zethelius B (2004b) Supplementation with trans10cis12-conjugated linoleic acid induces hyperproinsulinaemia in obese men: Close association with impaired insulin sensitivity. Diabetologia 47, 1016-1019.
24. Sartorio A, Lafortuna CL, Vangeli V, Tavani A, Bosetti C & La Vecchia C (2001) Short-term changes of cardiovascular risk factors after a non-pharmacological body weight reduction program. Eur J Clin Nutr 55, 865-869.
25. Stunkard AJ & Messick S (1985) The three-factor eating questionnaire to measure dietary restraint, disinhibition and hunger. J Psychosom Res 29, 71-83.
26. Terpstra AH (2001) Differences between humans and mice in efficacy of the body fat lowering effect of conjugated linoleic acid: Role of metabolic rate. J Nutr 131, 2067-2068.
27. Thom E, Wadstein J & Gudmundsen O (2001) Conjugated linoleic acid reduces body fat in healthy exercising humans. J Int Med Res 29 392-396.
28. Yoshizumi T, Nakamura T, Yamane M, Islam AH, Menju M, Yamasaki K, Arai T, Kotani K, Funahashi T, Yamashita S & Matsuzawa Y (1999) Abdominal fat: Standardized technique for measurement at CT. Radiology 211, 283-286.
29. Zambell KL, Keim NL, Van Loan MD, Gale B, Benito P, Kelley DS & Nelson GJ (2000) Conjugated linoleic acid supplementation in humans: Effects on body composition and energy expenditure. Lipids 35, 777-782.