Monocrotaline pyrrole induces Smad nuclear accumulation and altered signaling expression in human pulmonary arterial endothelial cells

Vascular Pharmacology

Volumn 46, Issue 6, 2007, Pages 439-448

  Ramos, M ^a   Lame M W ^b   Segall, H J ^b   Wilson, D W ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

BMPrII; Bone morphogenic protein; MCTP; Monocrotaline pyrrole; Smad signal transduction

Indexed keywords

ACTIVIN RECEPTOR LIKE KINASE 1; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 4; BONE MORPHOGENETIC PROTEIN RECEPTOR 2; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOCROTALINE PYRROLE; PHOSPHOTRANSFERASE; SMAD1 PROTEIN; SMAD2 PROTEIN; SMAD4 PROTEIN; SMAD6 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ARTERY ENDOTHELIUM; ARTICLE; CAVEOLA; CELL CULTURE; CELL NUCLEUS; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG MECHANISM; ENDOTHELIUM CELL; FEMALE; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN TRANSPORT; PULMONARY ARTERY; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ACTIVE TRANSPORT, CELL NUCLEUS; ALKYLATING AGENTS; BONE MORPHOGENETIC PROTEIN RECEPTORS, TYPE II; BONE MORPHOGENETIC PROTEINS; CAVEOLAE; CELL NUCLEUS; CELLS, CULTURED; CHILD, PRESCHOOL; ENDOTHELIAL CELLS; FEMALE; HUMANS; MONOCROTALINE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PULMONARY ARTERY; SIGNAL TRANSDUCTION; SMAD PROTEINS; SMAD1 PROTEIN; SMAD2 PROTEIN; SMAD4 PROTEIN; SMAD6 PROTEIN; TIME FACTORS; TRANSFECTION; TRANSFORMING GROWTH FACTOR BETA1;

EID: 34147136670     PISSN: 15371891     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vph.2007.01.005     Document Type: Article

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