Safety, acceptability, and tolerability of 3 topical microbicides among heterosexual Kenyan men

Journal of Acquired Immune Deficiency Syndromes

Volumn 44, Issue 4, 2007, Pages 423-428

  Bukusi, Elizabeth A ^a,b,c,d   Steele, Matthew ^c,e   Cohen, Craig R ^d,f   Nguti, Rosemary ^b   Maingi, Charity W ^a   Thomas, Katherine K ^c   Holmes, King K ^c  

^a KENYA MEDICAL RESEARCH INSTITUTE   (Kenya)

^b UNIVERSITY OF NAIROBI   (Kenya)

^c UNIVERSITY OF WASHINGTON   (United States)

^d UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^e Program for Appropriate Technology in Health   (United States)

^f UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Benzalkonium chloride; Crossover study; Ethanol gel; Male genital hygiene; Sexually transmitted infection; Topical microbicid

Indexed keywords

ALCOHOL; BENZALKONIUM CHLORIDE; ERYTHROMYCIN; MICROBICIDE;

ABRASION; ADULT; ARTICLE; BURNING SENSATION; CLINICAL ARTICLE; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DRUG SAFETY; DRUG TOLERABILITY; DRY SKIN; GENITAL ABRASION; GENITAL PRURITUS; GENITAL RASH; GENITAL ULCER; HETEROSEXUAL MALE; HUMAN; MALE; PENIS; PRIORITY JOURNAL; RASH; SEXUALLY TRANSMITTED DISEASE; TREATMENT RESPONSE; ULCUS MOLLE;

ADMINISTRATION, CUTANEOUS; ADULT; ANTI-INFECTIVE AGENTS; BENZALKONIUM COMPOUNDS; CROSS-OVER STUDIES; EMOLLIENTS; ETHANOL; GENITALIA, MALE; HETEROSEXUALITY; HUMANS; KENYA; MALE; PATIENT SATISFACTION; PENIS; PILOT PROJECTS; SEXUALLY TRANSMITTED DISEASES; TIME FACTORS; TREATMENT OUTCOME;

EID: 34147125374     PISSN: 15254135     EISSN: None     Source Type: Journal    
DOI: 10.1097/QAI.0b013e31802f852b     Document Type: Article

References (16)

1. Moore JE. The diagnosis of chancroid and the effect of prophylaxis on its incidence in the American Expeditionary Forces. J Urol. 1920;4:169-176.
2. O'Farrell N. Soap and water prophylaxis for limiting genital ulcer disease and HIV-1 infection in men in sub-Saharan Africa. Genitourin Med. 1993;69:297-300.
3. Sanderson PJ, Weissler S. A comparison of the effect of chlorhexidine antisepsis, soap and antibiotics on bacteriuria, perineal colonization and environmental contamination in spinally injured patients. J Hosp Infect. 1990;15:235-243.
4. Taha TE, Kumwenda N, Mwakomba A, et al. Safety, acceptability, and potential efficacy of a topical penile microbicide wipe. J Acquir Immune Defic Syndr. 2005;39:347-353.
5. Kampf G, Muscatiello M, Hantschel D, et al. Dermal tolerance and effect on skin hydration of a new ethanol-based hand gel. J Hosp Infect. 2002;52:297-301.
6. Carr MP, Sullivan S, Gilmore J, et al. Preference and compliance of waterless hand-hygiene products versus soap and water. Am J Dent. 2003;16:17A-19A.
7. Steele MS, Bukusi E, Cohen CR, et al. Male genital hygiene beliefs and practices in Nairobi, Kenya. Sex Transm Infect. 2004;80:471-476.
8. Paulson DS, Fendler EJ, Dolan MJ, et al. A close look at alcohol gel as an antimicrobial sanitizing agent. Am J Infect Control. 1999;27:332-338.
9. Zeger SL, Liang KY. Longitudinal data analysis for discrete and continuous outcomes. Biometrics. 1986;42:121-130.
10. Mancl LA, DeRouen TA. A covariance estimator for GEE with improved small-sample properties. Biometrics. 2001;57:126-134.
11. Efron B, Tibshirani RJ. An Introduction to the Bootstrap. New York: Chapman and Hall/CRC; 1998:141-142.
12. Buvé A, Caraël M, Hayes RJ, et al, for the Study Group on Heterogeneity of HIV Epidemics in African Cities. Multicentre study on factors determining differences in rate of spread of HIV in sub-Saharan Africa: methods and prevalence of HIV infection. AIDS. 2001;15(Suppl 4):S5-S14.
13. Kenya Department of Health Services. HIV prevalence and associated factors, Central Bureau of Statistics (CBS) Kenya, Ministry of Health (Kenya), and ORC Macro, Kenya Demographic and Health Survey 2003. Calverton, MD. 2003;220-232.
14. Kenya Department of Health Services. HIV/AIDS related attitudes and behavior, Central Bureau of Statistics (CBS), Ministry of Health (Kenya), and ORC Macro, Kenya Demographic and Health Survey 2003. Calverton, MD. 2003;183-219.
15. Bukusi EA, Cohen CR, Meier AS, et al. Bacterial vaginosis: risk factors among Kenyan women and their male partners. Sex Transm Dis. 2006;33:361-367.
16. Ezumah NN. Gender issues in the prevention and control of STIs and HIV/AIDS: lessons from Awka and Agulu, Anambra State, Nigeria. Afr J Reprod Health. 2003;7:89-99.