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Mechanism of antidiuretic effect of β-adrenergic stimulation
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Mechanism of effect of α adrenergic stimulation with norepinephrine on renal water excretion
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Berl T, Cadnapaphornchai P, Harbottle JA, Schrier RW: Mechanism of stimulation of vasopressin release during β adrenergic stimulation with isoproterenol. J Clin Invest (1974) 53(3):857-867. • This study demonstrated the role of arterial baroreceptors in the non-osmotic regulation of vasopressin during β-adrenergic stimulation.
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Berl T, Cadnapaphornchai P, Harbottle JA, Schrier RW: Mechanism of stimulation of vasopressin release during β adrenergic stimulation with isoproterenol. J Clin Invest (1974) 53(3):857-867. • This study demonstrated the role of arterial baroreceptors in the non-osmotic regulation of vasopressin during β-adrenergic stimulation.
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7
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Berl T, Cadnapaphornchai P, Harbottle JA, Schrier RW: Mechanism of suppression of vasopressin during α-adrenergic stimulation with norepinephrine. J Clin Invest (1974) 53(1):219-227. • This study demonstrated the role of arterial baroreceptors in the non-osmotic regulation of vasopressin during α-adrenergic stimulation.
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Berl T, Cadnapaphornchai P, Harbottle JA, Schrier RW: Mechanism of suppression of vasopressin during α-adrenergic stimulation with norepinephrine. J Clin Invest (1974) 53(1):219-227. • This study demonstrated the role of arterial baroreceptors in the non-osmotic regulation of vasopressin during α-adrenergic stimulation.
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8
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Dunn FL, Brennan TJ, Nelson AE, Robertson GL: The role of blood osmolality and in regulating vasopressin secretion in the rat. J Clin Invest (1973) 52(12):3212-3219. • This study demonstrated the relative sensitivity and potency of osmotic and non-osmotic regulation of vasopressin.
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Dunn FL, Brennan TJ, Nelson AE, Robertson GL: The role of blood osmolality and volume in regulating vasopressin secretion in the rat. J Clin Invest (1973) 52(12):3212-3219. • This study demonstrated the relative sensitivity and potency of osmotic and non-osmotic regulation of vasopressin.
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9
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2 vasopressin receptor on the basolateral surface of principal cells in the collecting duct has allowed the identification of numerous receptor mutations leading to vasopressin-resistant NDI.
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2 vasopressin receptor on the basolateral surface of principal cells in the collecting duct has allowed the identification of numerous receptor mutations leading to vasopressin-resistant NDI.
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Nielsen S, Frokiaer J, Marples D, Kwon T-H, Agre P, Knepper MA: Aquaporins in the kidney: From molecules to medicine. Physiol Rev (2002) 82(1):205-244. • An excellent review of the role of AQP water channels in health and disease, describing the different roles of the seven AQPs expressed within the kidney.
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Nielsen S, Frokiaer J, Marples D, Kwon T-H, Agre P, Knepper MA: Aquaporins in the kidney: From molecules to medicine. Physiol Rev (2002) 82(1):205-244. • An excellent review of the role of AQP water channels in health and disease, describing the different roles of the seven AQPs expressed within the kidney.
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Cadnapaphornchai MA, Summer SN, Falk S, Thurman JM, Knepper MA, Schrier RW: Effect of primary polydipsia on aquaporin and sodium transporter abundance. Am J Physiol Renal Physiol (2003) 285(5):F965-F971. • This study demonstrated the effect of the downregulation of the AQP-2 water channel in a urinary-concentrating defect secondary to polydipsia.
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2 vasopressin receptor antagonist to demonstrate the role of non-osmotic vasopressin and the upregulation of AQP-2 in impaired water excretion in hypothyroidism.
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2 vasopressin receptor antagonist to demonstrate the role of non-osmotic vasopressin and the upregulation of AQP-2 in impaired water excretion in hypothyroidism.
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2 vasopressin receptor antagonist to demonstrate the role of non-osmotic vasopressin and the upregulation of AQP-2 in impaired water excretion in hypothyroidism.
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2 vasopressin receptor antagonist to demonstrate the role of non-osmotic vasopressin and the upregulation of AQP-2 in impaired water excretion in hypothyroidism.
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Marples D, Christensen S, Christensen EI, Ottosen PD, Nielsen S: Lithium-induced downregulation of aquaporin-2 water channel expression in rat kidney medulla. J Clin Invest (1995) 95(4):1838-1845. • This paper and references [41•,42•,43•,44•,45•] report the effect of the downregulation of AQP-2 expression in acquired NDI.
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Marples D, Christensen S, Christensen EI, Ottosen PD, Nielsen S: Lithium-induced downregulation of aquaporin-2 water channel expression in rat kidney medulla. J Clin Invest (1995) 95(4):1838-1845. • This paper and references [41•,42•,43•,44•,45•] report the effect of the downregulation of AQP-2 expression in acquired NDI.
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41
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Marples D, Frokiaer J, Dorup J, Knepper MA, Nielsen S: Hypokalemia-induced downregulation of aquaporin-2 water channel expression in rat kidney medulla and cortex. J Clin Invest (1996) 97(8):1960-1968. • This paper and references [40•,42•, 43•,44•,45•] report the effect of the downregulation of AQP-2 expression in acquired NDI.
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Marples D, Frokiaer J, Dorup J, Knepper MA, Nielsen S: Hypokalemia-induced downregulation of aquaporin-2 water channel expression in rat kidney medulla and cortex. J Clin Invest (1996) 97(8):1960-1968. • This paper and references [40•,42•, 43•,44•,45•] report the effect of the downregulation of AQP-2 expression in acquired NDI.
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Earm JH, Christensen BM, Frokiaer J, Marples D, Han JS, Knepper MA, Nielsen S: Decreased aquaporin-2 expression and apical plasma membrane delivery in kidney collecting ducts of polyuric hypercalcemic rats. J Am Soc Nephrol (1998) 9(12):2181-2193. • This paper and references [40•,41•,43•,44•,45•] report the effect of the downregulation of AQP-2 expression in acquired NDI.
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Earm JH, Christensen BM, Frokiaer J, Marples D, Han JS, Knepper MA, Nielsen S: Decreased aquaporin-2 expression and apical plasma membrane delivery in kidney collecting ducts of polyuric hypercalcemic rats. J Am Soc Nephrol (1998) 9(12):2181-2193. • This paper and references [40•,41•,43•,44•,45•] report the effect of the downregulation of AQP-2 expression in acquired NDI.
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Frokiaer J, Marples D, Knepper MA, Nielsen S: Bilateral ureteral obstruction downregulates expression of vasopressin-sensitive AQP-2 water channel in rat kidney. Am J Physiol (1996) 270 (4 Pt 2):F657-F668. • This paper and references [40•,41•,42•, 44•,45•] report the effect of the downregulation of AQP-2 expression in acquired NDI.
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Frokiaer J, Marples D, Knepper MA, Nielsen S: Bilateral ureteral obstruction downregulates expression of vasopressin-sensitive AQP-2 water channel in rat kidney. Am J Physiol (1996) 270 (4 Pt 2):F657-F668. • This paper and references [40•,41•,42•, 44•,45•] report the effect of the downregulation of AQP-2 expression in acquired NDI.
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Kwon TH, Frokiaer J, Fernandez-Llama P, Knepper MA, Nielsen S: Reduced abundance of aquaporins in rats with bilateral ischemia-induced acute renal failure: Prevention by α-MSH. Am J Physiol (1999) 277(3 Pt 2):F413-F427. • This paper and references [40•,41•, 42•,43•,45•] report the effect of the downregulation of AQP-2 expression in acquired NDI.
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Kwon TH, Frokiaer J, Fernandez-Llama P, Knepper MA, Nielsen S: Reduced abundance of aquaporins in rats with bilateral ischemia-induced acute renal failure: Prevention by α-MSH. Am J Physiol (1999) 277(3 Pt 2):F413-F427. • This paper and references [40•,41•, 42•,43•,45•] report the effect of the downregulation of AQP-2 expression in acquired NDI.
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