Proteasome and NF-κB inhibiting phaeophytins from the green alga Cladophora fascicularis

Molecules

Volumn 12, Issue 3, 2007, Pages 582-592

  Huang, Xinping ^a,b   Li, Min ^a   Xu, Bo ^a   Zhu, Xiaobin ^b   Deng, Zhiwei ^c   Lin, Wenhan ^a  

^a PEKING UNIVERSITY   (China)

^b INSTITUTE OF OCEANOLOGY   (China)

^c BEIJING NORMAL UNIVERSITY   (China)

Author keywords

Cladophora fascicularis; Green alga; NF B; Porphyrinolactone; Proteasome

Indexed keywords

CHLOROPHYLL; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEASOME; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; GREEN ALGA; HELA CELL; HUMAN; ISOLATION AND PURIFICATION;

ALGAE, GREEN; CHLOROPHYLL; HELA CELLS; HUMANS; NF-KAPPA B; PROTEASOME ENDOPEPTIDASE COMPLEX; TUMOR NECROSIS FACTOR-ALPHA;

EID: 34147099442     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/12030582     Document Type: Article

References (26)

1. Duperon, R.; Thiersault, M.; Duperon, P. Occurrence of Steryl Glycosides and Acylated Steryl Glycosides in Some Marine Algae. Phytochemistry 1983, 22, 535-538.
2. Napoli, L.; Magno, S.; Mayol, L.; Novellino, E. Sterol Composition of Some Mediterranean Green Algae. Phytochemistry 1982, 21, 1993-1994.
3. Aknin, M.; Moellet-Nzaou, R.; Kornprobst, J. M.; Gaydou, E. M.; Samb, A.; Miralles, J. Sterol Composition of Twelve Chlorophyceae from the Senegalese Coast and Their Chemotaxonomic Significance. Phytochemistry 1992, 31, 4167-4169.
4. Elenkov, I.; Georgieva, T.; Dadjieva, P.; Dimitrova, S.; Dimitrova-Konaklieva, S.; Popov, S. Terpenoids and Sterols in Cladophora vagabunda. Phytochemistry 1995, 38, 457-459.
5. Koniyoshi, M.; Yamada, K.; Higa, T. Biologically Active Diphenyl Ether from the Green Alga Cladophora fascicularis. Experientia 1985, 41, 523-524.
6. Matsuo, A.; Ono, K.; Hamasaki, K.; Nozaki, H. Phaeophytins from A Cell Suspension Culture of the Liverwort Plagiochila ovalifolia. Phytochemistry 1996, 42, 427-430.
7. Buchanan, M. B.; Hashimoto, T.; Asakawa, Y. Phytyl Esters and Phaeophytins from the Hornwort Megaceros flagellaris. Phytochemistry 1996, 41, 1373-1376.
8. Senge, M.; Senger, H. Enzymic meso-Chlorination of Chlorphylls Using Chloroperoxidase. Biochim. Biophys. Acta 1989, 977, 177-186.
9. Nakatani, Y.; Ourisson, G.; Beck, J. P. Chemistry and Biochemistry of Chinese Drugs. VII Cytostatic Pheophytins from Silkworm Excreta and Derived Photocytotoxic Pheophorbides. Chem. Pharm. Bull. 1981, 29, 2261-2269.
10. 18O-Labeling and Mass Spectrometry. J. Org. Chem. 2002, 67, 4055-4061.
11. Riccardis, F.; Luigi, M. Marine Sterols. Side-Chain-Oxygenated Sterolds, Possibly of Abiotic Origin, from the New Caledonian Sponge Stelodoryx chlorophylla. J. Nat. Prod. 1993, 56, 282-287.
12. Tang, H.; Yi, Y.; Yao, X.; Zhou, D.; Lu, T.; Jiang, Y. Studies on the Bioactive Steroid Constituents form Sargassum carpophllum. Chin. Pharm. J. 2002, 37, 262-265.
13. Cabrera, C. M.; Seldes, A. M. Hydroperoxycycloartanes from Tillandsia recurvata. J. Nat. Prod. 1995, 58, 1920-1924.
14. Cabrera, C. M.; Gallo, M.; Seldes, A. M. Cycloartane Derivatives from Tillandsia usneoides. J. Nat. Prod. 1996, 59, 343-347.
15. Greca, M. D.; Fiorentino, A.; Monaco, P.; Previtera, L. Cycloartane Triterpenes from Juncus effusus. Phytochemistry 1994, 35, 1017-1022.
16. Li, G..; Wang, J.; Li, N.; Li, X. Cycloartane Triterpenoids from the Pericarp of Sphaerophysa salsula DC. J. Shengyang Pharma. Univ. 2003, 20, 252-254.
17. Heinrich, M.; Bork, P. M.; Schmitz, L.; Rimpler, H.; Frei, B.; Sticher, O. Pheaophorbide A from Solanum diflorum Interferes with NF-κB Activation. Planta Med. 2001, 67, 156-157.
18. Cheng, H.; Wang, H.; Ito, J.; Bastow, K. F.; Tachibana, Y.; Nakanishi, Y.; Xu, Z.; Luo, T.; Lee, K. Cytotoxic Pheophorbide-Related Compounds from Clerodendrum calamitosum and C. cyrtophyllum. J. Nat. Prod. 2001, 64, 915-919.
19. Kisselev, A.F.; Goldberg, A. L. Proteasome Inhibitors: from Research Tools to Drug Candidates. Chem. Biol. 2001, 8, 739-758.
20. Elliott, P. J.; Zollner, T. M.; Boehncke, W. H. Proteasome Inhibition: A New Anti-Inflammatory Strategy. J. Mol. Med. 2003, 81, 235-245.
21. Adams, J. Proteasome Inhibition: A Novel Approach to Cancer Therapy. Trends Mol. Med. 2002, 8S, 49-54.
22. Adams, J. The Proteasome: Structure, Function, and Role in the Cell. Cancer Treat Rev. Suppl 1 2003, 29, 3-9.
23. Um, J. H.; Kang, C. D.; Lee, B. G..; Kim, D. W.; Chung, B. S.; Kim, S. H. Increased and Correlated Nuclear Factor-Kappa B and Ku Autoantigen Activities are Associated with Development of Multidrug resistance. Oncogene 2001, 20, 6048-6056.
24. Giuliano, K. A.; Dunlay, D. R. L.; Gough, A.; Volosky, J. M.; Zock, J.; Pavlakis, G. N.; Taylor, D. L. High-Content Screening: A New Approach to Easing Key Bottlenecks in the Drug Discovery Process. J. Biomol. Screen. 1997, 2, 249-259.
25. Vakkila, J.; DeMarco, R. A.; Lotze, M. T. Imaging Analysis of STAT1 and NF-κB Translocation in Dendritic Cells at the Single Cell Level. J. Immuno. Methods 2004, 294, 123-134.
26. Bo, X.; Monsarrat, B.; Gairin, J. E.; Girbal-Neuhauser, E. Effect of Ajoene, A Natural Antitumor Small Molecule, on Human 20S Proteasome Activity in Vitro and in Human Leukemic HL-60 Cells. Fundam. Clin. Pharmacol. 2004, 18, 171-180.