The post-translational phenotype of collagen synthesized by SAOS-2 osteosarcoma cells

Bone

Volumn 40, Issue 5, 2007, Pages 1343-1351

  Fernandes, Russell J ^a   Harkey, Michael A ^a   Weis, Maryann ^a   Askew, Jennifer W ^a   Eyre, David R ^a,b  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Bone; Lysyl hydroxylase; Osteosarcoma; Protein mass spectrometry; Pyridinoline; Type I collagen; Type V collagen

Indexed keywords

COLLAGEN; COLLAGEN TYPE 1; COLLAGEN TYPE 11; COLLAGEN TYPE 5; LYSINE; LYSYLHYDROXYLASE 1; OXYGENASE; PYRIDINOLINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL LINE; COLLAGEN SYNTHESIS; CONTROLLED STUDY; CROSS LINKING; EXTRACELLULAR MATRIX; GENOME ANALYSIS; HUMAN; HUMAN CELL; HUMAN TISSUE; HYDROXYLATION; IMMUNOBLOTTING; NONHUMAN; OSTEOBLAST; OSTEOSARCOMA CELL; PHENOTYPE; PROTEIN EXPRESSION; PROTEIN PROCESSING; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

AMINO ACID SEQUENCE; CELL LINE, TUMOR; COLLAGEN; GENE EXPRESSION REGULATION; GENOME, HUMAN; HUMANS; LIVER; MOLECULAR SEQUENCE DATA; OSTEOSARCOMA; PHENOTYPE; PROCOLLAGEN-LYSINE, 2-OXOGLUTARATE 5-DIOXYGENASE; PROTEIN PROCESSING, POST-TRANSLATIONAL; RNA, MESSENGER;

EID: 34047269957     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2007.01.011     Document Type: Article

References (60)

1. Eyre D.R. Biochemical basis of collagen metabolites as bone turnover markers. In: Raisz L., Rodin G., and Bilezikian J.P. (Eds). Principles of bone biology (1996), Academic Press, London 43-152
2. Eyre D.R., and Wu J.J. Collagen cross-links. Top. Curr. Chem. 247 (2005) 207-229
3. Eyre D.R., Dickson I.R., and Van Ness K. Collagen cross-linking in human bone and articular cartilage. Age-related changes in the content of mature hydroxypyridinium residues. Biochem. J. 252 (1988) 495-500
4. Kivirikko K.I., and Myllyla R. Posttranslational enzymes in the biosynthesis of collagen: intracellular enzymes. Methods Enzymol. 82 Pt. A (1982) 245-304
5. Hautala T., Byers M.G., Eddy R.L., Shows T.B., Kivirikko K.I., and Myllyla R. Cloning of human lysyl hydroxylase: complete cDNA-derived amino acid sequence and assignment of the gene (PLOD) to chromosome 1p36.3-p36.2. Genomics 13 (1992) 62-69
6. Valtavaara M., Papponen H., Pirttila A.M., Hiltunen K., Helander H., and Myllyla R. Cloning and characterization of a novel human lysyl hydroxylase isoform highly expressed in pancreas and muscle. J. Biol. Chem. 272 (1997) 6831-6834
7. Valtavaara M., Szpirer C., Szpirer J., and Myllyla R. Primary structure, tissue distribution, and chromosomal localization of a novel isoform of lysyl hydroxylase (lysyl hydroxylase 3). J. Biol. Chem. 273 (1998) 12881-12886
8. Passoja K., Rautavuoma K., Ala-Kokko L., Kosonen T., and Kivirikko K.I. Cloning and characterization of a third human lysyl hydroxylase isoform. Proc. Natl. Acad. Sci. U. S. A. 95 (1998) 10482-10486
9. Yeowell H.N., and Walker L.C. Tissue specificity of a new splice form of the human lysyl hydroxylase 2 gene. Matrix Biol. 18 (1999) 179-187
10. van der Slot A.J., Zuurmond A.M., Bardoel A.F., Wijmenga C., Pruijs H.E., Sillence D.O., et al. Identification of PLOD2 as telopeptide lysyl hydroxylase, an important enzyme in fibrosis. J. Biol. Chem. 278 (2003) 40967-40972
11. Ruotsalainen H., Sipila L., Vapola M., Sormunen R., Salo A.M., Uitto L., et al. Glycosylation catalyzed by lysyl hydroxylase 3 is essential for basement membranes. J. Cell Sci. 119 (2006) 625-635
12. Heikkinen J., Risteli M., Wang C., Latvala J., Rossi M., Valtavaara M., et al. Lysyl hydroxylase 3 is a multifunctional protein possessing collagen glucosyltransferase activity. J. Biol. Chem. 275 (2000) 36158-36163
13. Walker L.C., Overstreet M.A., Siddiqui A., De Paepe A., Ceylaner G., Malfait F., et al. A novel mutation in the lysyl hydroxylase 1 gene causes decreased lysyl hydroxylase activity in an Ehlers-Danlos VIA patient. J. Invest. Dermatol. 124 (2005) 914-918
14. Walker L.C., Marini J.C., Grange D.K., Filie J., and Yeowell H.N. A patient with Ehlers-Danlos syndrome type VI is homozygous for a premature termination codon in exon 14 of the lysyl hydroxylase 1 gene. Mol. Genet. Metab. 67 (1999) 74-82
15. Krane S.M., Pinnell S.R., and Erbe R.W. Lysyl-protocollagen hydroxylase deficiency in fibroblasts from siblings with hydroxylysine-deficient collagen. Proc. Natl. Acad. Sci. U. S. A. 69 (1972) 2899-2903
16. Steinmann B., Eyre D.R., and Shao P. Urinary pyridinoline cross-links in Ehlers-Danlos syndrome type VI. Am. J. Hum. Genet. 57 (1995) 1505-1508
17. Eyre D., Shao P., Weis M.A., and Steinmann B. The kyphoscoliotic type of Ehlers-Danlos syndrome (type VI): differential effects on the hydroxylation of lysine in collagens I and II revealed by analysis of cross-linked telopeptides from urine. Mol. Genet. Metab. 76 (2002) 211-216
18. Bank R.A., Robins S.P., Wijmenga C., Breslau-Siderius L.J., Bardoel A.F., van der Sluijs H.A., et al. Defective collagen crosslinking in bone, but not in ligament or cartilage, in Bruck syndrome: indications for a bone-specific telopeptide lysyl hydroxylase on chromosome 17. Proc. Natl. Acad. Sci. U. S. A. 96 (1999) 1054-1058
19. Hanson D.A., and Eyre D.R. Molecular site specificity of pyridinoline and pyrrole cross-links in type I collagen of human bone. J. Biol. Chem. 271 (1996) 26508-26516
20. Lehmann H.W., Bodo M., Frohn C., Nerlich A., Rimek D., Notbohm H., et al. Lysyl hydroxylation in collagens from hyperplastic callus and embryonic bones. Biochem. J. 282 Pt. 2 (1992) 313-318
21. Shapiro F.D., and Eyre D.R. Collagen polymorphism in extracellular matrix of human osteosarcoma. J. Natl. Cancer Inst. 69 (1982) 1009-1016
22. Lehmann H.W., Wolf E., Roser K., Bodo M., Delling G., and Muller P.K. Composition and posttranslational modification of individual collagen chains from osteosarcomas and osteofibrous dysplasias. J. Cancer Res. Clin. Oncol. 121 (1995) 413-418
23. Bailey A.J., Wotton S.F., Sims T.J., and Thompson P.W. Post-translational modifications in the collagen of human osteoporotic femoral head. Biochem. Biophys. Res. Commun. 185 (1992) 801-805
24. Glimcher M.J., Shapiro F., Ellis R.D., and Eyre D.R. Changes in tissue morphology and collagen composition during the repair of cortical bone in the adult chicken. J. Bone Jt. Surg., Am. 62 (1980) 964-973
25. Acil Y., Springer I., Behrens P., Ullrich K.P., Hedderich J., and Bruns J. Differential enhancement of collagen crosslink excretion in cases of osteosarcoma and chondrosarcoma. J. Cancer Res. Clin. Oncol. 129 (2003) 583-588
26. Behrens P., Bruns J., Ullrich K.P., Acil Y., and Gille J. Pyridinoline cross-links as markers for primary and secondary bone tumors. Scand. J. Clin. Lab. Invest. 63 (2003) 37-44
27. Rodan S.B., Imai Y., Thiede M.A., Wesolowski G., Thompson D., Bar-Shavit Z., et al. Characterization of a human osteosarcoma cell line (Saos-2) with osteoblastic properties. Cancer Res. 47 (1987) 4961-4966
28. Pautke C., Schieker M., Tischer T., Kolk A., Neth P., Mutschler W., et al. Characterization of osteosarcoma cell lines MG-63, Saos-2 and U-2 OS in comparison to human osteoblasts. Anticancer Res. 24 (2004) 3743-3748
29. Murray E., Provvedini D., Curran D., Catherwood B., Sussman H., and Manolagas S. Characterization of a human osteoblastic osteosarcoma cell line (SAOS-2) with high bone alkaline phosphatase activity. J. Bone Miner. Res. 2 (1987) 231-238
30. Barrett M.G., Belinsky G.S., and Tashjian Jr. A.H. A new action of parathyroid hormone. receptor-mediated stimulation of extracellular acidification in human osteoblast-like SaOS-2 cells. J. Biol. Chem. 272 (1997) 26346-26353
31. Farley J.R., Hall S.L., Herring S., Tarbaux N.M., Matsuyama T., and Wergedal J.E. Skeletal alkaline phosphatase specific activity is an index of the osteoblastic phenotype in subpopulations of the human osteosarcoma cell line SAOS-2. Metabolism 40 (1991) 664-671
32. Schroder H.C., Boreiko O., Krasko A., Reiber A., Schwertner H., and Muller W.E. Mineralization of SaOS-2 cells on enzymatically (silicatein) modified bioactive osteoblast-stimulating surfaces. J. Biomed. Mater. Res., B Appl. Biomater. 75 (2005) 387-392
33. Fassina L., Visai L., Asti L., Benazzo F., Speziale P., Tanzi M.C., et al. Calcified matrix production by SAOS-2 cells inside a polyurethane porous scaffold, using a perfusion bioreactor. Tissue Eng. 11 (2005) 685-700
34. Fedde K.N. Human osteosarcoma cells spontaneously release matrix-vesicle-like structures with the capacity to mineralize. Bone Miner. 17 (1992) 145-151
35. McQuillan D.J., Richardson M.D., and Bateman J.F. Matrix deposition by a calcifying human osteogenic sarcoma cell line (SAOS-2). Bone 16 (1995) 415-426
36. Sevetson B., Taylor S., and Pan Y. Cbfa1/RUNX2 directs specific expression of the sclerosteosis gene (SOST). J. Biol. Chem. 279 (2004) 13849-13858
37. Bertaux K., Broux O., Chauveau C., Jeanfils J., and Devedjian J.C. Identification of CBFA1-regulated genes on SaOs-2 cells. J. Bone Miner. Metab. 23 (2005) 114-122
38. Cheng Y.Y., Huang L., Lee K.M., Li K., and Kumta S.M. Alendronate regulates cell invasion and MMP-2 secretion in human osteosarcoma cell lines. Pediatr. Blood Cancer 42 (2004) 410-415
39. Raval P., Hsu H.H., and Anderson H.C. Osteoinductive ability of confluent Saos-2 cell correlates with enhanced expression of bone morphogenetic proteins. J. Orthop. Res. 14 (1996) 605-610
40. Hunt T.R., Schwappach J.R., and Anderson H.C. Healing of a segmental defect in the rat femur with use of an extract from a cultured human osteosarcoma cell-line (Saos-2). A preliminary report. J. Bone Jt. Surg., Am. 78 (1996) 41-48
41. Goto T., Matsui Y., Fernandes R.J., Hanson D.A., Kubo T., Yukata K., et al. Sp1 family of transcription factors regulates the human alpha2 (XI) collagen gene (COL11A2) in Saos-2 osteoblastic cells. J. Bone Miner. Res. 21 (2006) 661-673
42. Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227 (1970) 680-685
43. Hauselmann H.J., Fernandes R.J., Mok S.S., Schmid T.M., Block J.A., Aydelotte M.B., et al. Phenotypic stability of bovine articular chondrocytes after long-term culture in alginate beads. J. Cell Sci. 107 Pt. 1 (1994) 17-27
44. Eyre D.R., Koob T.J., and Van Ness K.P. Quantitation of hydroxypyridinium crosslinks in collagen by high-performance liquid chromatography. Anal. Biochem. 137 (1984) 380-388
45. Fernandes R.J., Schmid T.M., and Eyre D.R. Assembly of collagen types II, IX and XI into nascent hetero-fibrils by a rat chondrocyte cell line. Eur. J. Biochem. 270 (2003) 3243-3250
46. Stegemann H. Microdetermination of hydroxyproline with chloramine-T and p-dimethylaminobenzaldehyde. Hoppe-Seyler's Z. Physiol. Chem. 311 (1958) 41-45
47. Fernandes R.J., Schmid T.M., Harkey M.A., and Eyre D.R. Incomplete processing of type II procollagen by a rat chondrosarcoma cell line. Eur. J. Biochem. 247 (1997) 620-624
48. Sambrook J., Fritsch E.F., and Maniatis T. Molecular cloning: a laboratory manual (1989), Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
49. Robbins J.R., Thomas B., Tan L., Choy B., Arbiser J.L., Berenbaum F., et al. Immortalized human adult articular chondrocytes maintain cartilage-specific phenotype and responses to interleukin-1beta. Arthritis Rheum. 43 (2000) 2189-2201
50. Bolton M.C., Dudhia J., and Bayliss M.T. Quantification of aggrecan and link-protein mRNA in human articular cartilage of different ages by competitive reverse transcriptase-PCR. Biochem. J. 319 Pt. 2 (1996) 489-498
51. Grandinetti K.B., Spengler B.A., Priedler J.L., and Ross R.A. Loss of one HuD allele on chromosome #1p selects for amplification of the N-myc proto-oncogene in human neuroblastoma cells. Oncogene 25 (2006) 706-712
52. Niyibizi C., and Eyre D.R. Identification of the cartilage alpha 1(XI) chain in type V collagen from bovine bone. FEBS Lett. 242 (1989) 314-318
53. Niyibizi C., and Eyre D.R. Bone type V collagen: chain composition and location of a trypsin cleavage site. Connect. Tissue Res. 20 (1989) 247-250
54. Keene D.R., Sakai L.Y., and Burgeson R.E. Human bone contains type III collagen, type VI collagen, and fibrillin: type III collagen is present on specific fibers that may mediate attachment of tendons, ligaments, and periosteum to calcified bone cortex. J. Histochem. Cytochem. 39 (1991) 59-69
55. Sugimoto M., Kimura T., Tsumaki N., Matsui Y., Nakata K., Kawahata H., et al. Differential in situ expression of alpha2(XI) collagen mRNA isoforms in the developing mouse. Cell Tissue Res. 292 (1998) 325-332
56. Matsui Y., Kimura T., Tsumaki N., Nakata K., Yasui N., Araki N., et al. Splicing patterns of type XI collagen transcripts act as molecular markers for osteochondrogenic tumors. Cancer Lett. 124 (1998) 143-148
57. Dominguez L.J., Barbagallo M., and Moro L. Collagen overglycosylation: a biochemical feature that may contribute to bone quality. Biochem. Biophys. Res. Commun. 330 (2005) 1-4
58. Erler J.T., Bennewith K.L., Nicolau M., Dornhofer N., Kong C., Le Q.T., et al. Lysyl oxidase is essential for hypoxia-induced metastasis. Nature 440 (2006) 1222-1226
59. Masi L., Franchi A., Santucci M., Danielli D., Arganini L., Giannone V., et al. Adhesion, growth, and matrix production by osteoblasts on collagen substrata. Calcif. Tissue Int. 51 (1992) 202-212
60. Engler A.J., Sen S., Sweeny H.L., and Discher D.E. Matrix elasticity directs stem cell lineage specification. Cell 126 (2006) 677-689