Potential thrombogenic complications with the use of recombinant activated factor VII in combat trauma

Clinical and Applied Thrombosis/Hemostasis

Volumn 13, Issue 2, 2007, Pages 121-123

  Fareed, Jawed ^a,g   Bick, Rodger L ^b   Kessler, Craig ^c   Messmore, Harry L ^a   Rao, Gundu ^d   Sasahara, Arthur ^e   Haas, Sylvia ^f  

^a LOYOLA UNIVERSITY MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c GEORGETOWN UNIVERSITY   (United States)

^d UNIVERSITY OF MINNESOTA   (United States)

^e HARVARD MEDICAL SCHOOL   (United States)

^f TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^g NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RECOMBINANT BLOOD CLOTTING FACTOR 7A;

BLEEDING; CLINICAL TRIAL; DRUG EFFICACY; DRUG SAFETY; EDITORIAL; FOOD AND DRUG ADMINISTRATION; GENETIC ENGINEERING; HEART INFARCTION; HEMOPHILIA; HUMAN; INJURY; LUNG EMBOLISM; PRACTICE GUIDELINE; PRIORITY JOURNAL; RISK ASSESSMENT; STROKE; THROMBOGENICITY; UPREGULATION;

FACTOR VII; HUMANS; RECOMBINANT PROTEINS; THROMBOSIS; WAR; WOUNDS AND INJURIES;

EID: 34047261425     PISSN: 10760296     EISSN: None     Source Type: Journal    
DOI: 10.1177/1076029606298733     Document Type: Editorial

References (4)

1. Hoots WK Challenges in the therapeutic use of a "so-called" universal hemostatic agent: recombinant factor VIIa. Hematology Am Soc Hematol Educ Program. 2005 ; 426-431.
2. Stein DM, Dutton RP, O'Connor J., Alexander M., Scalea TM Determinants of futility of administration of recombinant factor VIIa in trauma. Trauma. 2005 ; 59: 609-615.
3. MacLaren R. Weber LA, Brake H., Gardner MA, Tanzi M. A multicenter assessment of recombinant factor viia off-label usage: clinical experiences and associated outcomes. Transfusion. 2005 ; 45: 1434-1438.
4. Midla GS Recombinant factor VIIa and its clinical applications. Army Med Department Journal. PB 8-04-7/8/9 Jul/ Aug/Sep.