Characterization of the promoter of the gene encoding human tripeptidyl-peptidase II and identification of upstream silencer elements

Gene

Volumn 393, Issue 1-2, 2007, Pages 62-69

  Lindås, Ann Christin ^a   Tomkinson, Birgitta ^a  

^a UPPSALA UNIVERSITY   (Sweden)

Author keywords

EMSA; NF Y; Oct 1; pGL3; Transcriptional regulation; USF 1

Indexed keywords

CCAAT BINDING FACTOR; NUCLEAR FACTOR Y; OCTAMER TRANSCRIPTION FACTOR 1; PEPTIDASE; PROTEINASE; TRIPEPTIDYLPEPTIASE 2; UNCLASSIFIED DRUG; UPSTREAM STIMULATORY FACTOR;

ARTICLE; CELL TYPE; CONTROLLED STUDY; DNA PROTEIN COMPLEX; E BOX ELEMENT; GEL MOBILITY SHIFT ASSAY; HUMAN; HUMAN CELL; MUTATION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEGRADATION; PROTEIN EXPRESSION; SILENCER ELEMENT; TRANSCRIPTION INITIATION;

5' FLANKING REGION; BASE PAIRING; CELL LINE; DNA-BINDING PROTEINS; E-BOX ELEMENTS; ELECTROPHORETIC MOBILITY SHIFT ASSAY; HUMANS; LUCIFERASES; NUCLEAR PROTEINS; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; REPRESSOR PROTEINS; SERINE ENDOPEPTIDASES; SILENCER ELEMENTS, TRANSCRIPTIONAL; TRANS-ACTIVATION (GENETICS);

EID: 34047256400     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.gene.2007.01.015     Document Type: Article

References (22)

1. Alabert C., et al. Cell type-dependent control of NF-Y activity by TGF-beta. Oncogene 25 (2006) 3387-3396
2. Chand A., Wyke S.M., and Tisdale M.J. Effect of cancer cachexia on the activity of tripeptidyl-peptidase II in skeletal muscle. Cancer Lett. 218 (2005) 215-222
3. Corre S., and Galibert M.D. Upstream stimulating factors: highly versatile stress-responsive transcription factors. Pigment Cell Res. 18 (2005) 337-348
4. Gavioli R., Frisan T., Vertuani S., Bornkamm G.W., and Masucci M.G. c-myc overexpression activates alternative pathways for intracellular proteolysis in lymphoma cells. Nat. Cell Biol. 3 (2001) 283-288
5. Geier E., et al. A giant protease with potential to substitute for some functions of the proteasome. Science 283 (1999) 978-981
6. Glas R., Bogyo M., McMaster J.S., Gaczynska M., and Ploegh H.L. A proteolytic system that compensates for loss of proteasome function. Nature 392 (1998) 618-622
7. Groll M., Bochtler M., Brandstetter H., Clausen T., and Huber R. Molecular machines for protein degradation. ChemBioChem 6 (2005) 222-256
8. Hong X., Lei L., and Glas R. Tumors acquire inhibitor of apoptosis protein (IAP)-mediated apoptosis resistance through altered specificity of cytosolic proteolysis. J. Exp. Med. 197 (2003) 1731-1743
9. Liberati C., Ronchi A., Lievens P., Ottolenghi S., and Mantovani R. NF-Y organizes the gamma-globin CCAAT boxes region. J. Biol. Chem. 273 (1998) 16880-16889
10. Lindås A.C., and Tomkinson B. Identification and characterization of the promoter for the gene encoding human tripeptidyl-peptidase. Gene 345 (2005) 249-257
11. Liu M., Whetstine J.R., Payton S.G., Ge Y., Flatley R.M., and Matherly L.H. Roles of USF, Ikaros and Sp proteins in the transcriptional regulation of the human reduced folate carrier B promoter. Biochem. J. 383 (2004) 249-257
12. Luo X., and Sawadogo M. Functional domains of the transcription factor USF2: atypical nuclear localization signals and context-dependent transcriptional activation domains. Mol. Cell. Biol. 16 (1996) 1367-1375
13. Mantovani R. The molecular biology of the CCAAT-binding factor NF-Y. Gene 239 (1999) 15-27
14. Nicolas M., Noe V., and Ciudad C.J. Transcriptional regulation of the human Sp1 gene promoter by the specificity protein (Sp) family members nuclear factor Y (NF-Y) and E2F. Biochem. J. 371 (2003) 265-275
15. Ogbourne S., and Antalis T.M. Transcriptional control and the role of silencers in transcriptional regulation in eukaryotes. Biochem. J. 331 (1998) 1-14
16. Reits E., et al. A major role for TPPII in trimming proteasomal degradation products for MHC class I antigen presentation. Immunity 20 (2004) 495-506
17. Saur D., Seidler B., Paehge H., Schusdziarra V., and Allescher H.D. Complex regulation of human neuronal nitric-oxide synthase exon 1c gene transcription. Essential role of Sp and ZNF family members of transcription factors. J. Biol. Chem. 277 (2002) 25798-25814
18. Sirito M., Lin Q., Maity T., and Sawadogo M. Ubiquitous expression of the 43- and 44-kDa forms of transcription factor USF in mammalian cells. Nucleic Acids Res. 22 (1994) 427-433
19. Tomkinson B., and Lindås A.C. Tripeptidyl-peptidase II: a multi-purpose peptidase. Int. J. Biochem. Cell Biol. 37 (2005) 1933-1937
20. Viollet B., Lefrançois-Martinez A.M., Henrion A., Kahn A., Raymondjean M., and Martinez A. Immunochemical characterization and transacting properties of upstream stimulatory factor isoforms. J. Biol. Chem. 271 (1996) 1405-1415
21. Wang E.W., et al. Integration of the ubiquitin-proteasome pathway with a cytosolic oligopeptidase activity. Proc. Natl. Acad. Sci. U. S. A. 97 (2000) 9990-9995
22. Wray C.J., Tomkinson B., Robb B.W., and Hasselgren P.O. Tripeptidyl-peptidase II expression and activity are increased in skeletal muscle during sepsis. Biochem. Biophys. Res. Commun. 296 (2002) 41-47