Long term follow-up of a large cohort of inactive HBsAg(+)/HBeAg(-)/anti- HBe(+) carriers in Greece

Journal of Gastrointestinal and Liver Diseases

Volumn 16, Issue 1, 2007, Pages 19-22

  Gigi, Eleni ^a   Lalla, Thalia ^a   Orphanou, Eleni ^a   Sinakos, Emmanuel ^a   Vrettou, Eleni ^a   Raptopoulou Gigi, Maria ^a,b  

^a ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

^b Aristotle University of Thessaloniki   (Greece)

Author keywords

Chronic hepatitis B; HBVDNA; Inactive carrier

Indexed keywords

ALANINE AMINOTRANSFERASE; HEPATITIS B SURFACE ANTIGEN; HEPATITIS B(E) ANTIBODY; HEPATITIS B(E) ANTIGEN;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FOLLOW UP; GREECE; HEPATITIS B; HISTOPATHOLOGY; HUMAN; HYBRIDIZATION; LIVER BIOPSY; LIVER CELL CARCINOMA;

ADULT; CARRIER STATE; COHORT STUDIES; FEMALE; GREECE; HEPATITIS B; HEPATITIS B ANTIBODIES; HEPATITIS B E ANTIGENS; HEPATITIS B SURFACE ANTIGENS; HEPATITIS B, CHRONIC; HUMANS; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES; TIME FACTORS;

EID: 34047253752     PISSN: 18418724     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Mahoney FJ. Update on diagnosis, management and prevention of hepatitis B virus infection. Clin Microbiol Rev 1999; 12:351-366
2. Chang KM, Chisari FV. Immunopathogenesis of hepatitis B virus infection. Clinics Liv Dis 1999; 2: 221-239
3. Fattovich G, Brollo L, Giustina G. Natural history and prognostic factors for chronic hepatitis type B. Gut 1991; 32: 294-298
4. Chu C, Liaw YF. Natural history of chronic hepatitis B virus infection: an immunopathological study. J Gastroenterol Hepatol 1997; 12:S218-222
5. Fattovich G, Brollo L, Alberto A, et al. Long term follow up of antiHBe positive chronic active hepatitis B. Hepatology 1988; 8:1651-1654
6. Befeler AS, Di Bisceglie AM. Hepatitis B. Infect Dis Clin N Am 2000; 14: 617-632
7. Okamoto H, Tsuda F, Akahane Y, et al. Hepatitis B virus with mutations in the core promoter for an e antigen-negative phenotype in carriers with antibody to e antigen. J Virol 1994; 68:8102-8110
8. Hadziyannis SJ. Interferon alpha therapy in HBeAg-negative chronic hepatitis B: new data in support of long-term efficacy. J Hepatol 2002; 36:280-282.
9. Ishak K et al. Histological grading and staging of chronic hepatitis. J Hepatol 1995; 22:696-699
10. Desmet VJ, Gerber M, Hoofnagle JH, Manns M, Scheuer PJ. Classification of chronic hepatitis: diagnosis, grading and staging. Hepatology 1994; 19:1513-1520
11. Huo TI, Wu JC, Lee PC et al. Sero-clearance of hepatitis B surface antigen in chronic carriers does not necessarily imply a good prognosis. Hepatology 1998; 28: 231-236
12. Martinot-Peignoux M, Boyer N, Colombat M, et al. Serum hepatitis B virus DNA levels and liver histology in inactive HBsAg carriers. J Hepatol 2002; 36: 543-546
13. Villeneuve JP, Desrochers M, Infante-Rivard C, et al. A long-term follow-up study of asymptomatic hepatitis B surface antigen-positive carriers in Montreal. Gastroenterology 1994; 106:1000-1005
14. Lok AS, Heathcote EJ, Hoofnagle JH. Management of hepatitis B 2000, Summary of a Workshop. Gastroenterology 2001; 120:1828-1853
15. Manno M, Camma C, Schepis F, et al. Natural history of chronic HBV carriers in Northern Italy: morbitity and mortality after 30 years. Gastroenterology 2004; 127: 756-763
16. Perillo RP. Acute flares in chronic hepatitis B: the natural and unnatural history of an immunologically mediated liver disease. Gastroenterology 2001; 120:1009-1022
17. Hsu YS, Chien RN, Yeh CT, et al. Long-term outcome after spontaneous HBeAg seroconversion in patients with chronic hepatitis B. Hepatology 2002; 35:1522-1527
18. Bellentani S, Dal Molin G, Miglioli L, et al. Natural history of HBV infection: a 9 years follow-up of the Dionysos cohort. J Hepatol 2002; 36(suppl 1): 228
19. Bortolotti F, Jara P, Crivellaro C, et al. Outcome of chronic hepatitis B in Caucasian children during a 20-year observation period. J Hepatol 1998; 29: 184-190