Proliferative processes within the equine corpus luteum may depend on paracrine progesterone actions

Journal of Physiology and Pharmacology

Volumn 57, Issue SUPPL. 8, 2006, Pages 139-151

  Ferreira Dias, Graça ^a   Costa, A S ^a   Mateus, L ^a   Korzekwa, A ^b   Redmer, D A ^c   Skarzynski, D J ^b  

^a FACULDADE DE MEDICINA VETERINÁRIA   (Portugal)

^b INSTITUTE OF ANIMAL REPRODUCTION AND FOOD RESEARCH   (Poland)

^c NORTH DAKOTA STATE UNIVERSITY   (United States)

Author keywords

Corpus luteum; Mare; Nitric oxide; Onapristone; Pregnenolone; Progesterone; Prostaglandins

Indexed keywords

NITRIC ACID; ONAPRISTONE; PREGNENOLONE; PROGESTERONE; PROGESTERONE RECEPTOR; PROSTAGLANDIN E2;

ANGIOGENESIS; ANIMAL CELL; ANIMAL TISSUE; AUTOCRINE EFFECT; CELL DIVISION; CELL PROLIFERATION; CONFERENCE PAPER; CONTROLLED STUDY; CORPUS LUTEUM; COW; DRUG SYNTHESIS; ENDOTHELIUM CELL; FEMALE; HORMONE SYNTHESIS; HORSE; IN VITRO STUDY; MITOGENESIS; NONHUMAN; PARACRINE SIGNALING; PROGESTERONE BLOOD LEVEL; TISSUE CULTURE;

ANIMALS; CELL GROWTH PROCESSES; CORPUS LUTEUM; DINOPROSTONE; ENDOTHELIAL CELLS; FEMALE; GONANES; HORSES; NEOVASCULARIZATION, PHYSIOLOGIC; NITRIC OXIDE; PREGNENOLONE; PROGESTERONE;

EID: 34047243794     PISSN: 08675910     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (62)

1. Ginther OJ. Reproductive anatomy. In Reproductive Biology of the Mare - Basic and Applied Aspects, OJ Ginther (ed). Cross Plains, Wis: Equiservices, 1992, pp. 233-290.
2. AL-zi'abi MO, Watson ED, Fraser HM. Angiogenesis and vascular endothelial growth factor expression in the equine corpus luteum. Reproduction 2003; 125: 259-270.
3. Ferreira-Dias G, Pinto Bravo P, Mateus L, Redmer D, Medeiros J.A. Microvascularization and angiogenic activity of equine corpus lutea throughout the estrous cycle. Dom Anim Endoc 2006; 30:247-259.
4. Roberto da Costa RP, Branco V, Pessa P, Robalo Silva J, Ferreira-Dias G. Progesterone receptors and proliferating cell nuclear antigen expression in the equine luteal tissue. J Reprod Fert Devel 2005; 17: 659-666.
5. Rotchild I. The regulation of the mammalian corpus luteum. Rec Prog Horm Res 1981; 37: 183-198.
6. Chappell PE, Lydon JP, Conneely OM, O.Malley BW, Levine JE. Endocrine effects in mice carrying a null mutation for the progesterone receptor gene. Endocrinology 1997; 138: 4147-4152.
7. 2α is dependent on progesterone, oxytocin and prostaglandins. Biol Reprod 1999; 60: 1292-1298.
8. Kotwica J, Rekawiecki R, Duras M. Stimulatory influence of progesterone on its own synthesis in bovine corpus luteum. Bull Vet Inst Pulawy 2004; 48: 139-145.
9. Ottander U, Hosokawa K, Loi K, Bergh A, Ny T, Olofsson J. A putative stimulatory role of progesterone acting via progesterone receptors in the steroidogenic cells of the human corpus luteum. Biol Reprod 2000; 62: 655-663.
10. Rueda BR, Hendry IR, Hendry III WJ, Stormshak F, Slyden OD, Davis JS. Decreased progesterone levels and progesterone receptor antagonist promote apoptotic cell death in bovine luteal cells. Biol Reprod 2000; 62(2): 269-276.
11. Okuda K, Korzekwa A, Shibaya M, et al. Progesterone is a suppressor of apoptosis in bovine luteal cells. Biol Reprod 2004; 71: 2065-2071.
12. Liszewska E, Rekawiecki R, Kotwica J. Effect of progesterone on the expression of bax and bcl-2 and on caspase activity in bovine luteal cells. Prostaglandins other Lipid Mediators 2005: 67-81.
13. Batra S, Al-Hijji J. Characterization of nitric oxide synthase activity in rabbit uterus and vagina: downregulation by estrogen. Life Sciences 1998; 62: 2092-2100.
14. Roberto da Costa RP, Ferreira-Dias G, Mateus L, et al. Endometrial nitric oxide production and nitric oxide synthases in the equine endometrium: relationship with microvascular density during the estrous cycle. Dom Anim Endoc 2006; in press.
15. Rupnow HL, Phernetton TM, Shaw CE, Modrick ML, Bird IM, Magness RR. Endothelial vasodilator production by uterine and systemic arteries. VII. Estrogen and progesterone effects on eNOS. Am J Physiol Heart Circ Physiol 2001; 280: H1699-H1705.
16. van der Zee R, Murohara T, Luo Z, et al. Vascular endothelial growth factor/vascular permeability factor augments nitric oxide release from quiescent rabbit and human vascular endothelium. Circulation 1997; 95: 1030-1037.
17. Zheng J, Bird IM, Melsaether AN, Magness RR. Activation of the mitogen-activated protein kinase cascade is necessary but not sufficient for basic fibroblast growth factor- and epidermal growth factor-stimulated expression of endothelial nitric oxide synthase in ovine fetoplacental artery endothelial cells. Endocrinology 1999; 140 (3): 1399-1407.
18. Grasselli F, Basini G, Bussolati S, Tamanini C. Effects of VEGF and bFGF on proliferation and production of steroids and nitric oxide in porcine granulosa cells. Reprod Dom Anim 2002; 37: 362-368.
19. Jaroszewski JJ, Skarzynski DJ, Okuda K. Nitric oxide as a local regulator in the mamalian ovary. In Reproductive Biotechnology: Reproductive Biotecnology Update and its Related Physiology, H Miyamoto, N Manabe (eds). Elsevier Scientific Pub., Tokyo, Japan, 2001, pp. 105-112.
20. Pinto CRF, Paccamonti DL, Eilts BE, Short CR, Godke RA. Effect of nitric oxide synthase inhibitors on ovulation in hCG-stimulated mares. Therio 2002; 58(5): 1017-1026.
21. Jaroszewski JJ, Hansel W. Intraluteal administration of a nitric oxide synthase blocker stimulates progesterone and oxytocin secretion and prolongs the life span of the bovine corpus luteum. Proc Soc Exp Biol Med 2000; 224: 50-55.
22. Olson LM, Jones-Burton CM, Jablonka-shariff A. Nitric oxide decreases estradiol synthesis of rat luteinized ovarian cells: possible role for nitric oxide in functional luteal regression. Endocrinology 1996; 137: 3531-3539.
23. Gobetti A, Boiti C, Canali C, Zerani M. Nitric oxide synthase acutely regulates progesterone production by in vitro cultured rabbit corpora lutea. J Endocrinol 1999; 160: 275-283.
24. Johnson MC, Diaza HA, Stocco C, Palomino A, Devoto L, Veja M. Antisteroidogenic action of nitric oxide on human corpus luteum in vitro: mechanism of action. Endocrine 1999; 11: 31-36.
25. Skarzynski DJ, Jaroszewski JJ, Bah MM, et al. Administration of a nitric oxide synthase inhibitor counteracts prostaglandin F2-induced luteolysis in cattle. Biol Reprod 2003; 68: 1674-1681.
26. Weems YS, Lennon E, Uchima T, et al. Is nitric oxide luteolytic or antiluteolytic? Prostaglandins Other Lipid Mediat 2005; 78: 129-138.
27. Motta AB, Estevez A, Tognetti T, Gimeno MAF, Franchi AM. Dual effects of nitric oxide in functional and regressing rat corpus luteum. Mol Human Reprod 2001; 7(1): 43-47.
28. Wiltbank MC, Ottobre JS. Regulation of intraluteal production of prostaglandins. Reprod Biol Endocrin 2003; 1: 91-112.
29. Lancaster MV, Fields RD. Antibiotic and cytotoxic drug susceptibility assays using reazurin and poising agents. 1996; U.S. Patent No. 5,501,959.
30. Redmer DA, Grazul AT, Kirsch DJ, Reynolds LP. Angiogenic activity of bovine corpora lutea at several stages of luteal development. J Reprod Fert 1988; 82: 627-634.
31. Jaroszewski JJ, Bogacki M, Skarzynski DJ. Progesterone production in bovine luteal cells treated with drugs that modulate nitric oxide production. Reproduction 2003; 125: 389.395.
32. 2α-induced oxytocin secretion and intracellular calcium mobilization in cultured bovine luteal cells. Biol Reprod 2000; 63:1000-1005.
33. Meschia G. Circulation to female reproductive organs. In Handbook of Physiology. JT Shepherd, FM Abboud (eds). Bethesda, American Physiological Society, 1983, Vol 3, part 1. pp. 241-269.
34. Stouffer RL, Martinez-Chequer JC, Molsknee TA, Xu F, Hazzard TM. Regulation and action of angiogenic factors in primate ovary. Arch Med Res 2001; 32: 567-575.
35. Girsh E, Greber Y, Meidan R. Luteotrophic and luteolytic interaction between bovine small and large luteal-like cells and endothelial cells. Biol Reprod 1995; 52: 954-962.
36. Davis JS, Rueda BR, Spanel-Borowski K. Microvascular endothelial cells of the corpus luteum. Reprod Biol Endocrinol 2003;1: 89-103.
37. Ferreira-Dias G, Mateus L, Costa AS, et al. Progesterone and caspase-3 activity in equine cyclic corpora lutea. Reprod Domest Anim 2006; (in press).
38. Hazzard TM, Rohan RM, Molskness TA, Fanton JW, Dámato RJ, Stouffer RL. Injection of antiangiogenic agents into the macaque preovulatory follicle: disruption of corpus luteum development and function. Endocrine 2002; 17: 199-206.
39. Maisonpierre PC, Suri C, Jones PF, et al. Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis. Science 1997; 277: 55-60.
40. Espinosa Cervantes MC, Rosado Garcia A. Angiogenesis in reproductive physiology. Follicular development, formation and maintenance of the corpus luteum. Gynecol Obstet Mex 2002; 70: 17-27.
41. Tamanini C, De Ambrogi M. Angiogenesis in developing follicle and corpus luteum. Reprod Domest Anim 2004; 39: 206-216.
42. 2α, progesterone and oxytocin in basal and pulsatile progesterone release from developing bovine corpus luteum. Prostaglandins Other Lipid Mediat 2006; 79: 218-229.
43. 4 and LH concentrations. Prostaglandins 1980; 20: 641-647.
44. Iwai M, Hasegawa M, Taii S, et al. Endothelins inhibit luteinization of cultured porcine granulosa cells. Endocrinology 1991; 129: 1909-1914.
45. Van Rensburg SJ, van Niekerk CH. Ovarian function, follicular oestradiol-17β, and luteal progesterone and 20α-hydroxypregn-4-en-3- one in cycling and pregnant equines. Ondersepoort J Vet Res 1968; 35:3 01-318.
46. Peluso JJ. Placing progesterone in the apoptotic pathway. Trends Endocrinol Metab 1997; 8: 267-271.
47. Collins S, Lohse MJ, O'Down B, Caron MG, Lefkowitz RJ. Structure and regulation of G protein-coupled receptors: the β2-adrenergic receptors as a model. Vitam Horm 1991; 46: 1-37.
48. Lohse MJ. Molecular mechanisms of membrane receptor desensitization. Biochim Biophys Acta 1993; 1179: 171-188.
49. Wiltbank MC, Belfiore CJ, Niswender GD. Steroidogenic enzyme activity after acute activation of protein kinase (PK) A and PKC in ovine small and large luteal cells. Mol Cell Endocrinol 1993; 97: 1-7.
50. 2α, and progesterone secretion by bovine corpora lutea of midpregnancy in vitro. Chin J Physiol 2002; 45: 163-168.
51. 2α and progesterone by ovine corpora lutea of pregnancy or the estrous cycle. Prostaglandins 2001; 63: 189-203.
52. Garrett JE, Geisert RD, Zavy MT, Morgan GL. Evidence for maternal regulation of early conceptus growth and development in beef cattle. J Reprod Fert 1988; 84: 437-446.
53. Ottobre JS, Lewis GS, Thayne WZ, Inskeep EK. Mechanism by which progesterone shortens the estrous cycle of the ewe. Biol Reprod 1980; 23:1046-1053.
54. Diaz FJ, Anderson LE, YL Wu, Rabot A, Tsai SJ, Wiltbank MC. Regulation of progesterone and prostaglandin F2α production in the CL. Mol Cel Endocrinol 2002; 191: 65-80.
55. 2 not LH regulates secretion of progesterone in vitro by the 88-90 day ovine corpus luteum of pregnancy. Prostaglandins 1997; 153: 337-353.
56. Weems YS, Lammoglia MA, Vera-Avila HR, et al. Effect of luteinizing hormone, PGE2, 8-EPI-PGE1, 8-EPI-PGE2, trichosanthin, and pregnancy specific protein B on secretion of progesterone in vitro by corpora lutea from nonpregnant and pregnant cows. Prostaglandins Other Lipid Mediat 1988; 55: 27-42.
57. Watson ED, Sertich PL. Secretion of prostaglandins and progesterone by cells from corpora lutea of mares. J Reprod Fertil 1990; 88(1): 223-229.
58. 2-9- ketoreductase in ovarian tissues. J Reprod Fertil 1979; 57: 489-496.
59. 2-9-ketoreductase activity in cyclic and pregnant ewes. Prostaglandins 1992; 44: 37-42.
60. 2 reductase: effector of oxytocin and interferon-τ. Biol Reprod 2000; 62: 125-131.
61. 2α in the bovine endometrium. J Biol Chem 2003; 278: 11205-11212.
62. Sugino N, Telleria CM, Gibori G. Progesterone inhibits 20a-hydroxysteroid dehydrogenase expression in the rat corpus luteum through the glucocorticoid receptor. Endocrinology 1997;138: 4497-4500.