Effect of ethanol extract of alga Laurencia supplementation on DNA oxidation and alkylation damage in mice

Asia Pacific Journal of Clinical Nutrition

Volumn 16, Issue SUPPL.1, 2007, Pages 164-168

  Liang, Hui ^a,b   He, Juan ^b   Ma, Ai Guo ^b   Zhang, Pei Hua ^b   Bi, Shu Lian ^b   Shi, Dayong ^c  

^a OCEAN UNIVERSITY OF CHINA   (China)

^b QINGDAO UNIVERSITY   (China)

^c INSTITUTE OF OCEANOLOGY   (China)

Author keywords

DNA damage; Laurencia; O6 methylguanine; SCGE; Terpenoid

Indexed keywords

DNA; HYDROGEN PEROXIDE; PLANT EXTRACT; SCAVENGER;

ANIMAL; BIOASSAY; CHEMISTRY; COMET ASSAY; CONFERENCE PAPER; DNA DAMAGE; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; LAURENCIA; LYMPHOCYTE; METABOLISM; MOUSE; OXIDATION REDUCTION REACTION; RANDOMIZATION;

ANIMALS; BIOLOGICAL ASSAY; COMET ASSAY; DNA; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; FREE RADICAL SCAVENGERS; HYDROGEN PEROXIDE; LAURENCIA; LYMPHOCYTES; MICE; OXIDATION-REDUCTION; PLANT EXTRACTS; RANDOM ALLOCATION;

ALGAE; ANIMALIA; LAURENCIA; MUS; RHODOPHYTA; TRISTICHA;

EID: 34047234236     PISSN: 09647058     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (31)

1. Le Tutour B. Antioxidative activities of alga extracts, synergistic effect with vitamin E. Phytochemistry 199029:3759-3765
2. Yan X, Nagata T, Fan X. Antioxidative activities in some common seaweeds. Plant Foods Hum Nutr1998;52:253-262
3. Fnical, W. Natural chemistry of the marine environment. Science 1982;215:923-928.
4. Liang H, He J, Zhang S C. Anticancer activities and immunologic function of Laurencia terpenoids. Chin J Mar Drugs 2005;24:6-9.
5. He J, Liang H, Shi D Y. Studies on the antioxidant activities of Laurencia extract in mice. Chin J Pubic Health 2005;21:1082-1083.
6. Singh NP, McCoy MT, Tice RR, Schneider EL. A simple technique for quantitation of low levels of DNA damage in individual cells. Experimental Cell Research 1988;184-191.
7. Anderson D, Yu TW, Phillips BJ, Schmezer P. The effects of various antioxidants and other modifying agents on oxygen-radical-generated DNA damage in human lymophcytes in the Comet assay. Mutation Res1994;307 261-271.
8. 6 -methylguanine. Chin J Chrom 2000; 18: 187-188.
9. Fairbairn DW, Olive PL, O'Neill KL. The Comet assay: a comprehensive review. Mutat Res 1995;339:37-59.
10. Ross GM, McMillan TJ, Wilcox P, Collins AR. The single cell microgel electrophoresis assay Comet assay: technical aspects and applications. Mutat Res 1994; 337: 57-60.
11. Tice RR, Strauss GHS. The single cell gel electrophoresisrComet assay: a potential tool for detecting radiation-induced DNA damage in humans, in: TM Fliedner, EP Cronkite, VP Bond Eds. , Assessment of Radiation Effects by Molecular and Cellular Approaches, AlphaMed Press, Dayton, OH, Stem Cells, 1995;13: 207-214.
12. Farinati F, Cardin R, Degan P. Oxidative DNA damage accumulation in gastric carcinogenesis. Gut 1998;42: 351-356.
13. Cooke MS, Mistry N, Wood C, Herbert KE, Lunec J. Immunogenicity of DNA damaged by reactive oxygen species - implications for anti-DNA antibodies in lupus. Free Radic Biol Med 1997;22: 151-159.
14. Darely-Usmer V, Halliwell B. Blood radicals: reactive nitrogen species, reactive oxygen species, transition metal ions, and the vascular system. Pharmacol Res1996;13:649-662.
15. Parthasarathy S, Steinberg D, Witztum JL. The role of oxidized LDL in the pathogenesis of arteriosclerosis. Annu Rev Med 1992;43: 219-225.
16. Nakazono K, Watanabe N, Matsuno K, Sasaki J, Sato T, Inoue M. Does superoxide underlie the pathogenesis of hypertension? Proc Natl Acad Sci USA 1991;88: 10045-10048.
17. Halliwell B, Gutterridge JMC. Lipidperoxidation, oxygen radicals,cell damage and antioxidant therapy. Lancet 1994;1:1396-1397.
18. Durackova Z. Oxidative stress. In: Durackova Z, Bergendi L, Carsky J. Free radicals and antioxidants in medicine (II).Slovak Academic Press, Bratislava 1999; 11-38.
19. Halliwell B. Reactive oxygen species in living systems: source, biochemistry and role in human disease. Annales Journal of Medicine 1991;(Suppl. 3C):14S-22S.
20. Labieniec M, Gabryelak T, Falcioni G. Antioixidant and prooxidant effects in digestive cells of the freshwater mussel Unio tumidus. Mutat. Res. 2003;539:19-28.
21. Tew KD, Colvin M, Chabner BA. Alkylating agents, in: B.A.Chabner, D. Longo (Eds.), Cancer Chemotherapy: Principles and Practice, second ed., J.B. Lippincott Co. Philadelphia 1996;297-332.
22. Beranek DT. Distribution of methyl and ethyl adducts following alkylation with monofunctional alkylating agents. Mutat Res 1990;231:11-30.
23. 6-alkylguanine-DNA alkyltransferase:role in carcinogenicity and chemotherapy. BioEssays 2002;24:255-266.
24. Kaina B, Fritz G, Mitra S, Coquerelle T. Transfection and expression of human O6-methylguanine-DNA methyltransferase (MGMT) cDNA in Chinese hamster cells: the role of MGMT in protection against the genotoxic effects of alkylating agents. Carcinogenesis 1991;12:1857-1867.
25. Kaina B, Christmann M. DNA repair in resistance to alkylating anticancer drugs. Int J Clin Pharm Ther 2002;40:354-367.
26. Kaina B, Fritz G, Coquerelle T. Contribution of O6-alkylguanine and N-alkylpurines to the formation of sister chromatid exchanges, chromosomal aberrations, and gene mutations: new insights gained from studies of genetically engineered mammalian cell lines. Environ Mol Mutagen 1993;22:283-292.
27. Kaina B, Ziouta A, Ochs K, Coquerelle T. Chromosomal instability, reproductive cell death and apoptosis induced by O6-methylguanine in Mex., Mex+ and methylationtolerant mismatch repair compromised cells: facts and models. Mutat Res 1997;381:227-241.
28. Tominaga Y, Tsuzuki T, Shiraishi A, Kawate H, Sekiguchi M. Alkylation-induced apoptosis of embryonic stem cells in which the gene for DNA-repair, methyltransferase, had been disrupted by gene targeting. Carcinogenesis 1997;18:889-896.
29. 6-alkylguanine DNA lesions trigger apoptosis. Carcinogenesis 1998;19:369-372.
30. 6- methylguanine is Bcl-2 and caspase-9/3 regulated and Fas/caspase-8 independent. Cancer Res 2000;60:5815-5824.
31. 6-methylguanine-DNA methyltransferase. Proc Natl Acad Sci USA 2001;98:12566-12571.