Oxcarbazepine in bipolar disorder: A critical review of the literature

Expert Opinion on Pharmacotherapy

Volumn 8, Issue 5, 2007, Pages 649-656

  Mazza, Marianna ^a   Di Nicola, Marco ^a   Martinotti, Giovanni ^a   Taranto, Colombo ^a   Pozzi, Gino ^a   Conte, Gianluigi ^a   Janiri, Luigi ^a   Bria, Pietro ^a   Mazza, Salvatore ^a  

^a CATHOLIC UNIVERSITY   (Italy)

Author keywords

Bipolar disorder; Depression; Mania; Oxcarbazepine

Indexed keywords

25 HYDROXYVITAMIN D; CARBAMAZEPINE; CYTOCHROME P450 2C19; ESTROGEN; FLUOXETINE; LITHIUM; OLANZAPINE; OXCARBAZEPINE; PLACEBO; PROGESTERONE; SERTRALINE; VALPROIC ACID; VENLAFAXINE; ANTICONVULSIVE AGENT; DRUG DERIVATIVE;

ADD ON THERAPY; ADJUVANT THERAPY; AGE DISTRIBUTION; ATAXIA; BIPOLAR DISORDER; BREAST MILK; CLINICAL EFFECTIVENESS; CLINICAL TRIAL; COMBINATION CHEMOTHERAPY; COMORBIDITY; DIZZINESS; DRUG BLOOD LEVEL; DRUG DOSE INCREASE; DRUG DOSE TITRATION; DRUG ELIMINATION; DRUG MEGADOSE; DRUG SAFETY; DRUG WITHDRAWAL; ENZYME INDUCTION; ENZYME INHIBITION; EPILEPSY; FATIGUE; HEADACHE; HUMAN; HYPONATREMIA; MANIA; MAXIMUM PLASMA CONCENTRATION; MEDLINE; META ANALYSIS; MONOTHERAPY; NAUSEA AND VOMITING; PANIC; PARKINSONISM; PATIENT MONITORING; RASH; REVIEW; SCHIZOAFFECTIVE PSYCHOSIS; SECONDARY HYPERPARATHYROIDISM; SEDATION; SIDE EFFECT; SLEEP DISORDER; SODIUM BLOOD LEVEL; SOMNOLENCE; SWEATING; SYSTEMATIC REVIEW; TERATOGENICITY; TINNITUS; TRANQUILIZING ACTIVITY; VERTIGO; WATER INTOXICATION; WEIGHT GAIN; EXPERT WITNESS; PRACTICE GUIDELINE;

ANTICONVULSANTS; BIPOLAR DISORDER; CARBAMAZEPINE; CLINICAL TRIALS; EXPERT TESTIMONY; HUMANS; PRACTICE GUIDELINES;

EID: 34047217726     PISSN: 14656566     EISSN: None     Source Type: Journal    
DOI: 10.1517/14656566.8.5.649     Document Type: Review

References (30)

1. KRUGER S, YOUNG LT, BRAUNIG P: Pharmacotherapy of bipolar mixed states. Bip. Disord. (2005) 7:205-215.
2. HELLEWELL JSE: Oxcarbazepine (Trileptal) in the treatment of bipolar disorders: a review of efficacy and tolerability. J. Affect. Disord. (2002) 72:S23-S34.
3. FRENCH JA, KANNER AM, BAUTISTA J et al.: Efficacy and tolerability of the new antiepileptic drugs II: treatment of refractory epilepsy; a report of the Therapeutics and technology assessment subcommittee and quality standards subcommittee of the American Academy of Neurology and the American Epilepsy Society. Neurology (2004) 62:1261-1273.
4. AMERICAN PSYCHIATRIC ASSOCIATION (APA): Practice guidelines for the treatment of patients with bipolar disorder (revision). Am. J. Psychiatry (2002) 159(S4):1-50.
5. SUPPES T, DENNEHY EB, SWANN AC: Report of the Texas Consensus Conference Panel on Medication Treatment of Bipolar Disorder. J. Clin. Psy. (2000) 63:288-299.
6. KETTER TA, WANG PW, BECKER OV et al.: The diverse roles of anticonvulsants in bipolar disorders. Ann. Clin. Psychiatry (2003) 15(2):95-108.
7. MAY TW, KORN-MERKER E, RAMBECK B: Clinical pharmacokinetics of oxcarbazepine. Clin. Pharmacokinet. (2003) 42:1023-1042.
8. SCHMIDT D, ELGER CE: What is the evidence that oxcarbazepine and carbamazepine are distinctly different antiepileptic drugs? Epilepsy Behav. (2004) 5:627-635.
9. PRATOOMSRI W, YATHAM LN, BOND DJ et al.: Oxcarbazepine in the treatment of bipolar disorder: a review. Can. J. Psychiatry (2006) 51(8). 540-545.
10. GOODNICK PJ: Anticonvulsants in the treatment of bipolar mania. Expert. Opin. Pharmacoter. (2006) 7(4):401-410.
11. LOFGEN E, TAPANAINEN JS, KOIVUNEN R et al.: Effects of carbamazepine and oxcarbazepine on the reproductive endocrine function in women with epilepsy. Epilepsia (2006) 47(9):1441-1446.
12. VAN AMELSVOORT T, BAKSHI R, DEVAUX CB et al.: Hyponatremia associated with carbamazepine and oxcarbazepine therapy: a review. Epilepsia (1994) 35(1):181-188.
13. DONG X, LEPPIK IE, WHITE J: Hyponatremia from oxcarbazepine and carbamazepine. Neurology (2005) 65:1976-1978.
14. MAVRAGANI CP, PANAYIOTIS G, VLACHOYIANNOPOULOS G: Is polydipsia sometimes the cause of oxcarbazepine-induced hyponatremia? Eur. J. Int. Med. (2005) 16:296-297.
15. SACHDEO RC, WASSERSTEIN A, MESENBRINK PJ: Effects of oxcarbazepine on sodium concentration and water handling. Neurology (2002) 51:613-620.
16. MINTZER S, BOPPANA P, TOGURI J: Vitamin D levels and bone turnover in epilepsy patients taking carbamazepine or oxcarbazepine. Epilepsia (2006) 47(3):510-515.
17. JEFFERSON J: Oxcarbazepine in bipolar disorder. Prim. Care Compan. J. Clin. Psy. (2001) 3(4):181.
18. EMRICH HM, ALTMANN H, DOSE M: Therapeutic effects of GABA-ergic drugs in affective disorders: a preliminary report. Pharmacol. Biochem. Behav. (1983) 19:369-373.
19. EMRICH HM: Studies with oxcarbazepine (Trileptal) in acute mania. Int. Clin. Psychopharmacol. (1990) 5(S1):83-88.
20. HUMMEL B, WALDEN J, STAMPFER R: Acute antimanic efficay anf safety of oxcarbazepine in an open trial with an on-off-on design. Bip. Disord. (2002) 4:412-417.
21. GHAEMI SN, BERV DA, KLUGMAN J: Oxcarbazepine treatment of bipolar disorder. J. Clin. Psy. (2003) 64:943-945.
22. RAJA M, AZZONI A: Oxcarbazepine versus valproate in the treatment of mood and schizoaffective disorders. Int. J. Neuropsychopharmacol. (2003) 6:409-414.
23. CENTORRINO F, ALBERT MJ, BERRY JM et al.: Oxcarbazepine: clinical experience with hospitalized psychiatric patients. Bip. Disord. (2003) 5:370-374.
24. BENEDETTI A, LATTANZI L, PINI S: Oxcarbazepine as add-on treatment in patients with bipolar manic, mixed or depressive episode. J. Affect. Disord. (2004) 79:273-277.
25. PRATOOMSRI W, YATHAM LN, SOHN CH: Oxcarbazepine add-on in the treatment of refractory bipolar disorder. Bip. Disord. (2005) 7(5):37-42.
26. MATTES JA: Oxcarbazepine in patients with impulsive aggression: a double-blind, placebo-controlled trial. J. Clin. Psychopharmacol. (2005) 25(6):575-579.
27. CONWAY CR, CHIBNALL JT, NELSON LA et al.: An open-label trial of adjunctive oxcarbazepine for bipolar disorder. J. Clin. Psychopharmacol. (2006) 26(1):95-97.
28. WAGNER KD, KOWATCH RA, EMSLIE GJ et al.: A double-blind, randomized, placebo-controlled trial of oxcarbazepine in the treatment of bipolar disorder in children and adolescents. Am. J. Psychiatry (2006) 163:1179-1186.
29. MORENO RA, HUPFELD MORENO D, DE MACEDO SOARES MB et al.: Anticonvulsants and antipsychostics in the treatment of bipolar disorder. Rev. Bras. Psi. (2004) 26(S III):37-43.
30. MAZZA M, BRIA P, MAZZA S: Efficacy and safety of oxcarbazepine (OXC) in bipolar disorder. Can. J. Psychiatry In press.