Valproate is an effective, well-tolerated drug for treatment of status epilepticus/serial attacks in adults

Acta Neurologica Scandinavica

Volumn 115, Issue SUPPL.187, 2007, Pages 51-54

  Olsen, K B ^a   Tauboll E ^a,b   Gjerstad, L ^a,b  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

^b UNIVERSITY OF OSLO   (Norway)

Author keywords

Humans; Serial attacks; Status epilepticus; Valproate

Indexed keywords

BARBITURIC ACID DERIVATIVE; DIAZEPAM; MIDAZOLAM; PROPOFOL; SODIUM CHLORIDE; VALPROIC ACID; ANESTHETIC AGENT; ANTICONVULSIVE AGENT;

ADULT; AGED; CHRONOTHERAPY; CLINICAL ARTICLE; CLINICAL PROTOCOL; CLINICAL TRIAL; CONFERENCE PAPER; CONTINUOUS INFUSION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; EPILEPTIC STATE; FEMALE; FOCAL EPILEPSY; GENERAL ANESTHESIA; HUMAN; HYPOTENSION; LOADING DRUG DOSE; MALE; MULTICENTER STUDY; NORWAY; PROSPECTIVE STUDY; RECOMMENDED DRUG DOSE; REGISTER; SYMPTOMATOLOGY; TONIC CLONIC SEIZURE; ARTICLE; DOSE RESPONSE; DRUG ADMINISTRATION; EMERGENCY HEALTH SERVICE; EPILEPSY; MIDDLE AGED; PATHOPHYSIOLOGY; STANDARD; TIME; TREATMENT OUTCOME;

ADULT; AGED; AGED, 80 AND OVER; ANESTHETICS, GENERAL; ANTICONVULSANTS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; EMERGENCY MEDICAL SERVICES; EPILEPSY; FEMALE; HUMANS; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; STATUS EPILEPTICUS; TIME FACTORS; TREATMENT OUTCOME; VALPROIC ACID;

EID: 34047209006     PISSN: 00016314     EISSN: 16000404     Source Type: Journal    
DOI: 10.1111/j.1600-0404.2007.00847.x     Document Type: Conference Paper

References (17)

1. VIGNATELLI L, TONON C, D'ALESSANDRO R. Incidence and short-term prognosis of status epilepticus in Bologna, Italy. Epilepsia 2003;44:964-8.
2. KANKE S, ROSENOW F, VESCOVI M, et al. Incidence of status epilepticus in adults in Germany: a prospective, population-based study. Epilepsia 2001;42:714-18.
3. COEYTAUX A, JALLON P, GALOBARDES B, MORABIA A. Incidence of status epilepticus in French-speaking Switzerland. Neurology 2000;55:693-7.
4. DELORENZO RJ, HAUSER WA, TOWNE AR, et al. A prospective, population-based epidemiologic study of status epilepticus in Richmond, Virginia. Neurology 1996;46:1029-35.
5. LOWENSTEIN DH, ALLDREDGE BK. Status epilepticus at an urban public hospital in the 1980s. Neurology 1993;43:483-98.
6. ALLDREDGE BK, GELB AM, ISAACS SM, et al. A comparison of lorazepam, diazepam and placebo for the treatment of out-of-hospital status epilepticus. N Engl J Med 2001;345:631-7.
7. LOWENSTEIN DH, BLECK T, MACDONALD RL. Its time to revise the definition of status epilepticus. Epilepsia 1999;40:120-2.
8. MISRA UK, KALITA J, PATEL R. Sodium valproate vs phenytoin in status epilepticus: a pilot study. Neurology 2006;67:340-2.
9. LIMDI NA, SHIMPI AV, FAUGHT E, GOMEZ CR, BURNEO JG. Efficacy of rapid IV administration of valproic acid for status epilepticus. Neurology 2005;64:353-5.
10. PETERS CNA, POHLMANN-EDEN B. Intravenous valproate as an innovative therapy in seizure emergency situations including status epilepticus - experience in 102 adult patients. Seizure 2005;14:164-9.
11. KRÄMER G, BERGMANN A, DESPLAND PA, et al. Derzeitiger Stellenwert intravenöser Valproinsäure in der Therapie des generalisierten tonisch-klonischen Status epilepticus. Aktuel Neurol 2005;32:247-310.
12. ÜBERALL MA, TROLLMANN R, WUNSIEDLER U, WENZEL D. Intravenous valproate in pediatric epilepsy patients with refractory status epilepticus. Neurology 2000;54:2188-9.
13. WATERHOUSE EJ. Status epilepticus. Curr Treat Options Neurol 2002;4:309-34.
14. SCHOLTES FB, RENIER WO, MEINARDI H. Generalized convulsive status epilepticus; causes, therapy and outcome in 346 patients. Epilepsia 1994;35:1104-12.
15. DEVINSKY O, LEPPIK I, WILLMORE LJ, et al. Safety of intravenous valproate. Ann Neurol 1995;38:670-4.
16. SHORT DW, PACK AM, BAZIL CW. Depacon administration, safety, and efficacy in a hospital setting. Epilepsia 1999;40(suppl. 7):226.
17. LIMDI NA, FAUGHT E. Safety of rapid infusion of intravenous valproic acid. Epilepsia 1999;40(suppl. 7):144.