A controlled trial of paroxetine for chronic PTSD, dissociation, and interpersonal problems in mostly minority adults

Depression and Anxiety

Volumn 24, Issue 2, 2007, Pages 77-84

  Marshall, Randall D ^a   Lewis Fernandez, Roberto ^a   Blanco, Carlos ^a   Simpson, H Blair ^a   Lin, Shu Hsing ^a   Vermes, Donna ^a   Garcia, Wendy ^a   Schneier, Franklin ^a   Neria, Yuval ^a   Sanchez Lacay, Arturo ^a   Liebowitz, Michael R ^a  

^a NEW YORK STATE PSYCHIATRIC INSTITUTE   (United States)

Author keywords

Dissociation; Interpersonal; Minority; Paroxetine; PTSD

Indexed keywords

PAROXETINE; PLACEBO;

ADULT; ARTICLE; BLURRED VISION; CHRONIC DISEASE; CLINICAL STUDY; CLINICAL TRIAL; CONFLICT; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISSOCIATIVE DISORDER; DOUBLE BLIND PROCEDURE; DRUG DOSE INCREASE; DRUG DOSE REGIMEN; DRUG EFFICACY; DRUG TOLERABILITY; FEMALE; HUMAN; HUMAN RELATION; MAINTENANCE THERAPY; MAJOR CLINICAL STUDY; MALE; MINORITY GROUP; NOSE CONGESTION; OUTPATIENT; PHOTOPHOBIA; POSTTRAUMATIC STRESS DISORDER; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RATING SCALE; SIDE EFFECT; SINGLE BLIND PROCEDURE; SYMPTOMATOLOGY; TREATMENT RESPONSE; TREMOR; URBAN AREA; WEIGHT GAIN;

ADULT; AFRICAN CONTINENTAL ANCESTRY GROUP; ANTIDEPRESSIVE AGENTS, SECOND-GENERATION; CHRONIC DISEASE; DISSOCIATIVE DISORDERS; DOUBLE-BLIND METHOD; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; FOLLOW-UP STUDIES; HISPANIC AMERICANS; HUMANS; INTERPERSONAL RELATIONS; MALE; MIDDLE AGED; PAROXETINE; PERSONALITY ASSESSMENT; STRESS DISORDERS, POST-TRAUMATIC; URBAN POPULATION;

EID: 34047178438     PISSN: 10914269     EISSN: 15206394     Source Type: Journal    
DOI: 10.1002/da.20176     Document Type: Article

References (49)

1. Beckham JC, Lytle BL, Feldman ME. 1996. Caregiver burden in partners of Vietnam war veterans with posttraumatic stress disorder. J Consult Clin Psychol 64:1068-1072.
2. Bernstein-Carlson EB, Putnam FW. 1986. Development, reliability, and validity of a dissociation scale. J Nerv Ment Dis 174:727-735.
3. Blake DD, Weathers FW, Nagy LM, Kaloupek DG, Gusman FD, Charney DS, Keane TM. 1995. The development of a Clinician-Administered PTSD Scale. J Trauma Stress 8:75-90.
4. Blanchard EB, Buckley TC, Hickling EJ, Taylor AE. 1998. Posttraumatic stress disorder and comorbid major depression: Is the correlation an illusion? J Anxiety Disord 12:21-37.
5. Blanco C, Lipsitz J, Caligor E. 2001. Treatment of chronic depression with a 12-week program of interpersonal psychotherapy. Am J Psychiatry 158:371-375.
6. Brady K, Pearlstein T, Asnis GM, Baker D, Rothbaum B, Sikes CR, Farfel GM. 2000. Efficacy and safety of sertraline treatment of posttraumatic stress disorder. JAMA 283:1837-1844.
7. Breslau N, Davis GC, Andreski P, Peterson E. 1991. Traumatic events and posttraumatic stress disorder in an urban population of young adults. Arch Gen Psychiatry 48:216-222.
8. Breslau N, Kessler RC, Chilcoat HD, Schultz LR, Davis GC, Andreski P. 1998. Trauma and posttraumatic stress disorder in the community: The 1996 Detroit Area Survey of Trauma. Arch Gen Psychiatry 55:626-632.
9. Carlier IVE, Lamberts RD, Fouwels AJ, Gersons BPR. 1996. PTSD in relation to dissociation in traumatized police officers. Am J Psychiatry 153:1325-1328.
10. Cloitre M, Scarvalone P, Difede JA. 1997. Posttraumatic stress disorder, self- and interpersonal dysfunction among sexually retraumatized women. J Trauma Stress 10:437-452.
11. Connor KM, Sutherland SM, Tupler LA, Malik ML, Davidson JRT. 1999. Fluoxetine in post-traumatic stress disorder: Randomized, double-blind study. Br J Psychiatry 175:17-22.
12. Cordova MJ, Andrykowski MA, Kenady DE, McGrath PC, Sloan DA, Red WH. 1995. Frequency and correlates of posttraumatic stress disorder like symptoms after treatment for breast cancer. J Consult Clin Psychol 63:981-986.
13. Davidson J, Pearlstein T, Londborg P, Brady KT, Rothbaum B, Bell J, Maddock R, Hegel MT, Farfel G. 2001. Efficacy of sertraline in preventing relapse of posttraumatic stress disorder: Results of a 28-week double-blind, placebo-controlled study. Am J Psychiatry 158:1974-1981.
14. Davidson JRT, Hughes D, Blazer D, George LK. 1991. Posttraumatic stress disorder in the community: An epidemiological study. Psychol Med 21:1-19.
15. Ferrada-Noli M, Asberg M, Ormstad K, Lundin T, Sundbom E. 1998. Suicidal behavior after severe trauma: Part 1. PTSD diagnoses, psychiatric comorbidity, and assessments of suicidal behavior. J Trauma Stress 11:103-112.
16. First MB, Spitzer RL, Gibbon M, William, JBW. 1997. Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I). Washington, DC: American Psychiatric Press.
17. Foa EB, Rothbaum BO, Riggs DS, Murdock TB. 1991. Treatment of posttraumatic stress disorder in rape victims: A comparison between cognitive-behavioral procedures and counseling. J Consult Clin Psychol 59:715-723.
18. Galea S, Ahern J, Resnick H, Kilpatrick D, Bucuvalas M, Gold J, Vlahov D. 2002. Psychological sequelae of the September 11 terrorist attacks in New York City. N Engl J Med 346:982-987.
19. Gibbons RD, Hedeker D, Waternaux C, Davis JM. 1988. Random regression models: A comprehensive approach to the analysis of longitudinal psychiatric data. Psychopharmacol Bull 24:438-443.
20. Hamilton M. 1960. A rating scale for depression. J Neurol Neurosurg Psychiatry 23:56-62.
21. Hamilton M. 1969. Diagnosis and ratings of anxiety. Br J Psychiatry 3:76-79.
22. Hertzberg MA, Feldman ME, Beckham JC, Kudler HS, Davidson JR. 2000. Lack of efficacy for fluoxetine in PTSD: A placebo controlled trial in combat veterans. Ann Clin Psychiatry 12:101-105.
23. Horowitz LM, Rosenberg SE, Baer BA, Ureno G, Villasenor VS. 1988. Inventory of Interpersonal Problems: Psychometric properties and clinical applications. J Consult Clin Psychol 56:885-892.
24. Kessler RC, Sonnega A, Bromet E, Hughes M, Nelson CB. 1995. Posttraumatic stress disorder in the National Comorbidity Survey. Arch Gen Psychiatry 52:1048-1060.
25. Londborg PD, Hegel MT, Goldstein S, Goldstein D, Himmelhoch JM, Maddock R, Patterson W, Rausch J, Farfel GM. 2001. Sertraline treatment of posttraumatic stress disorder: Results of a 24-week open-label extension study. J Clin Psychiatry 62:325-331.
26. Marcos LR, Cancro R. 1982. Pharmacotherapy of Hispanic depressed patients: Clinical observations. Am J Psychother 36:505-512.
27. Marks I, Lovell K, Noshirvani H, Livanou M, Thrasher S. 1998. Treatment of posttraumatic stress disorder by exposure and/or cognitive restructuring: A controlled study. Arch Gen Psychiatry 55:317-325.
28. Marshall RD, Beebe KL, Oldham M, Zaninelli R. 2001. Efficacy and safety of paroxetine treatment of chronic PTSD: A fixed-dosage, multi-center, placebo-controlled study. Am J Psychiatry 158:1982-1988.
29. Marshall RD, Schneier FR, Knight CBG, Abbate LA, Fallon BA, Goetz D, Campeas R, Liebowitz MR. 1998. An open trial of paroxetine in patients with noncombat-related chronic PTSD. J Clin Psychopharmacol 18:10-18.
30. Marshall RD, Vaughan SC, Mackinnon RA, Mellman L, Roose SP. 1997. Assessing outcome in psychoanalysis and long-term psychodynamic psychotherapy. J Am Acad Psychoanal 24:575-604.
31. Martenyi F, Brown EB, Zhang H, Koke SC, Prakash A. 2002. Fluoxetine v. placebo in prevention of relapse in post-traumatic stress disorder. Br J Psychiatry 181:315-320.
32. McFarlane AC, Atchison M, Rafalowicz E, Papay P. 1994. Physical symptoms in posttraumatic stress disorder. J Psychosom Res 38:715-726.
33. Mendoza R, Smith MW, Poland RE, Lin KM, Strickland TL. 1991. Ethnic psychopharmacology: The Hispanic and Native American perspective. Psychopharmacol Bull 27:449-461.
34. Pole N, Best SR, Weiss DS, Metzler T, Liberman AM, Fagan J, Marmar CR. 2001. Effects of gender and ethnicity on duty-related posttraumatic stress symptoms among urban police officers. J Nerv Ment Dis 189:442-448.
35. Quitkin FM, Stewart JW, McGrath PJ, Nunes E, Ocepek-Welikson K, Tricamo E, Rabkin JG, Ross D, Klein DF. 1993. Loss of drug effects during continuation therapy. Am J Psychiatry 150:562-565.
36. Riggs DS, Byrne CA, Weathers FW, Litz BT. 1998. The quality of the intimate relationships of male Vietnam veterans: Problems associated with posttraumatic stress disorder. J Trauma Stress 11:87-101.
37. Ruefl AM, Litz BT; Schlenger WE. 2000. Hispanic ethnicity and risk for combat-related posttraumatic stress disorder. Cult Divers Ethnic Minority Psychol 6:235-251.
38. Sánchez-Lacay JA, Lewis-Fernández R, Goetz D, Blanco C, Salman E, Davies, S. Liebowitz MR. 2001. Open trial of nefazodone among Hispanics with major depression: Efficacy, tolerability, and adherence issues. Depress Anxiety 13:118-124.
39. Sullivan HS. 1953. The interpersonal theory of psychiatry. New York: Norton.
40. Tucker P, Zaninelli R, Yehuda R, Ruggiero L, Dillingham K, Pitts CD. 2001. Paroxetine in the treatment of chronic posttraumatic stress disorder: Results of a placebo-controlled, flexible-dosage trial. J Clin Psychiatry 62:86-88.
41. U.S. Bureau of the Census, Population Division. 2003. Table ST-EST2002-ASPRO-01. Released September 18, 2003. Washington, DC: U.S. Government Printing Office.
42. Van der Kolk BA, Dreyfull D, Michaels M, Shera D, Berkowitz R, Fisler R, Saxe G. 1994. Fluoxetine in posttraumaric stress disorder. J Clin Psychiatry 55:517-522.
43. Wagner D, Heinrichs M, Ehlert U. 1998. Prevalence of symptoms of posttraumatic stress disorder in German professional firefighters. Am J Psychiatry 155:1727-1732.
44. Wagner GJ, Maguen S, Rabkin JG. 1998. Ethnic differences in response to fluoxetine in a controlled trial with depressed HIV-positive patients. Psychiatr Serv 49:239-240.
45. Ward JH, Laird NM. 1982. Random-effects models for longitudinal data. Biometrics 38:963-974.
46. Warshaw MG, Fierman E, Pratt L, Hunt M, Yonkers KA, Massion AO, Keller MB. 1993. Quality of life and dissociation in anxiety disorder patients with histories of trauma or PTSD. Am J Psychiatry 150:1512-1516.
47. Weathers FW, Keane TM, Davidson JRT. 2001. The Clinician-Administered PTSD Scale: A review of the first ten years of research. Depress Anxiety 13:132-156.
48. Wenninger K, Heiman JR. 1998. Relating body image to psychological and sexual functioning in child sexual abuse survivors. J Trauma Stress 11:543-623.
49. Yehuda R, Elkin A, Binder-Brynes K, Kahana B, Southwick SM, Schmeidler J, Giller EL. 1996. Dissociation in aging Holocaust survivors. Am J Psychiatry 153:935-940.