Synthetic study on telomerase inhibitor, D8646-2-6: Synthesis of the key intermediate using Sn(OTf)2 or Sc(OTf)3 mediated aldol-type reaction and stille coupling

Chemical and Pharmaceutical Bulletin

Volumn 55, Issue 3, 2007, Pages 495-499

  Kanai, Akira ^a   Takeda, Yoshifumi ^a   Kuramochi, Kouji ^a   Nakazaki, Atsuo ^a   Kobayashi, Susumu ^a  

^a TOKYO UNIVERSITY OF SCIENCE   (Japan)

Author keywords

Aldol type reaction; Carbohydrate containing pyrone; Scandium triflate; Stille coupling; Tin triflate; Vinyl stannane which contains phosphonate

Indexed keywords

ALDEHYDE; C 3 PYRANOSYL 4 HYDROXY 2 PYRONE DERIVATIVE; D8646 2 6; PYRONE DERIVATIVE; SCANDIUM; TELOMERASE INHIBITOR; TIN; UNCLASSIFIED DRUG;

ALDOL REACTION; ARTICLE; DRUG DESIGN; DRUG STRUCTURE; DRUG SYNTHESIS;

CATALYSIS; ENZYME INHIBITORS; GLYCOSIDES; MOLECULAR STRUCTURE; SCANDIUM; TELOMERASE; TIN COMPOUNDS;

EID: 34047171283     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.55.495     Document Type: Article

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