Study on the mechanism of trichlorfon-induced inhibition of progesterone synthesis in mouse leydig tumor cells (MLTC-1)

Toxicology

Volumn 234, Issue 1-2, 2007, Pages 51-58

  Hong, Xia ^a   Qu, Jianhua ^a   Wang, Yubang ^a   Sun, Hong ^a   Song, Lin ^a   Wang, Shoulin ^a   Wang, Xinru ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Mouse Leydig tumor cells (MLTC 1); P450 side chain cleavage enzyme (P450scc); Progesterone; Steroidogenic acute regulatory protein (StAR); Trichlorfon

Indexed keywords

3(OR 17)BETA HYDROXYSTEROID DEHYDROGENASE; CHOLERA TOXIN; CHOLESTEROL MONOOXYGENASE (SIDE CHAIN CLEAVING); CHORIONIC GONADOTROPIN; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYTOCHROME P450; FORSKOLIN; MESSENGER RNA; METRIFONATE; ORGANOPHOSPHATE PESTICIDE; PROGESTERONE; STEROIDOGENIC ACUTE REGULATORY PROTEIN;

ANIMAL CELL; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROGESTERONE SYNTHESIS; PROTEIN EXPRESSION; REPRODUCTION; STEROIDOGENESIS; TUMOR CELL;

3-HYDROXYSTEROID DEHYDROGENASES; ADENYLATE CYCLASE; ANIMALS; CELL LINE, TUMOR; CELL SURVIVAL; CHOLERA TOXIN; CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME; CHORIONIC GONADOTROPIN; CYCLIC AMP; DOSE-RESPONSE RELATIONSHIP, DRUG; FORSKOLIN; GENE EXPRESSION; GTP-BINDING PROTEINS; HUMANS; INSECTICIDES; INTRACELLULAR FLUID; LEYDIG CELL TUMOR; MICE; PHOSPHOPROTEINS; PROGESTERONE; RECEPTORS, LH; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRICHLORFON;

EID: 34047169220     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2007.01.022     Document Type: Article

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