Epoxygenase eicosanoids: Synthesis of tetrahydrofuran-diol metabolites and their vasoactivity

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 9, 2007, Pages 2634-2638

  Falck, J R ^a   Manmohan Reddy, L ^a   Byun, Kihwan ^a   Campbell, William B ^b   Yi, Xiu Yu ^b  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

EETs; Eicosanoids; Epoxygenase; Tetrahydrofuran; Vasorelaxation

Indexed keywords

EPOXYICOSATRIENOIC ACID; GLUCOSE; ICOSANOID; TETRAHYDROFURAN DERIVATIVE;

ARTICLE; CONCENTRATION RESPONSE; COW; DRUG POTENCY; DRUG SYNTHESIS; NONHUMAN; OXIDATION; REDUCTION; STRUCTURE ACTIVITY RELATION; VASODILATATION;

ANIMALS; ARTERIES; CATTLE; CHEMISTRY, PHARMACEUTICAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DESIGN; EICOSANOIDS; FURANS; MODELS, CHEMICAL; MOLECULAR CONFORMATION; OXYGENASES; STEREOISOMERISM; VASODILATION; VASODILATOR AGENTS;

BOVINAE;

EID: 34047164656     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.01.096     Document Type: Article

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