High-throughput screening for norepinephrine transporter inhibitors using the FLIPRTetra

Journal of Biomolecular Screening

Volumn 12, Issue 3, 2007, Pages 436-441

  Wagstaff, Ryan ^a   Hedrick, Michael ^a   Fan, Jun ^b   Crowe, Paul D ^a,b   DiSepio, Daniel ^a,c  

^a Neurocrine Bisciences Inc   (United States)

^b NEUROCRINE BIOSCIENCES INC   (United States)

^c JOHNSON AND JOHNSON PHARMACEUTICAL RESEARCH AND DEVELOPMENT   (United States)

Author keywords

FLIPRTetra; Fluorescent substrate; Norepinephrine; Transporter

Indexed keywords

4 (4 DIMETHYLAMINOSTYRYL) N METHYLPYRIDINIUM; ATOMOXETINE; CLOMIPRAMINE; DESIPRAMINE; DULOXETINE; FLUORESCENT DYE; NISOXETINE; NORADRENALIN; NORADRENALIN UPTAKE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; BIOASSAY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG BINDING; DRUG POTENCY; EMBRYO; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; IC 50; ISOTOPE LABELING; LIGAND BINDING; LIGHT EMITTING DIODE; PLATING MEDIUM; PRIORITY JOURNAL; REPRODUCIBILITY;

ADRENERGIC UPTAKE INHIBITORS; CELL LINE; DRUG EVALUATION, PRECLINICAL; HUMANS; INHIBITORY CONCENTRATION 50; KINETICS; NOREPINEPHRINE PLASMA MEMBRANE TRANSPORT PROTEINS; PYRIDINIUM COMPOUNDS;

EID: 34047158667     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057106297994     Document Type: Article

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