Protective effects of insulin on polychlorinated biphenyls-induced disruption of actin cytoskeleton in hippocampal neurons

Environmental Toxicology

Volumn 22, Issue 2, 2007, Pages 152-158

  Tang, Feige ^a   Yan, Chonghuai ^a   Li, Fei ^a   Wu, Shenghu ^a   Yu, Yongguo ^a   Gao, Yu ^a   Jin, Xingming ^a   Tian, Ying ^a   Shen, Xiaoming ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Cofilin; Filamentous actin; Insulin; LIM kinase 1; Polychlorinated biphenyls

Indexed keywords

COFILIN PHOSPHORYLATION; CYTOSKELETON; FILAMENTOUS ACTINS; PROTECTIVE EFFECTS;

CELL CULTURE; ENZYME INHIBITION; INSULIN; NEURONS; PHOSPHORYLATION; POLYCHLORINATED BIPHENYLS;

CYTOTOXICITY;

ACTIN; AROCLOR 1254; COFILIN; INSULIN; INSULIN RECEPTOR; LIM KINASE 1; NEUROPROTECTIVE AGENT; POLYCHLORINATED BIPHENYL; PROTEIN KINASE; UNCLASSIFIED DRUG;

BRAIN; ENZYME ACTIVITY; HORMONE; INHIBITION; PCB; POLYMERIZATION; PROTEIN; SIGNAL; TOXICITY;

ACTIN FILAMENT; ACTIN POLYMERIZATION; ANIMAL CELL; ARTICLE; BRAIN INJURY; CONTROLLED STUDY; CYTOPATHOGENIC EFFECT; CYTOSKELETON; DRUG MECHANISM; HIPPOCAMPUS; LEARNING; MEMORY; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT;

ACTIN DEPOLYMERIZING FACTORS; ACTINS; ANIMALS; AROCLOR 1254; CELL SURVIVAL; CELLS, CULTURED; CYTOSKELETON; HIPPOCAMPUS; HYPOGLYCEMIC AGENTS; INSULIN; NEURONS; NEUROPROTECTIVE AGENTS; PROTEIN KINASES; RATS; RATS, SPRAGUE-DAWLEY;

EID: 34047151300     PISSN: 15204081     EISSN: 15227278     Source Type: Journal    
DOI: 10.1002/tox.20247     Document Type: Article

References (32)

1. Arber S, Barbayannis FA, Hanser H, Schneider C, Stanyon CA, Bernard O, Caroni P. 1998. Regulation of actin dynamics through phosphorylation of cofilin by LIM-kinase. Nature 393:805-809.
2. Ayotte P, Muckle G, Jacobson JL, Jacobson SW, Dewailly É. 2003. Assessment of pre- and postnatal exposure to polychlorinated biphenyls: Lessons from the Inuit Cohort Study. Environ Health Perspect 111:1253-1258.
3. Belluji U, Lichtenberger L, Galaburda A, Korenberg JR. 1999. Bridging cognition, the brain and molecular genetics: Evidence from Williams syndrome. Trends Neurosci 22:197-207.
4. Bemis JC, Seegal RF. 1999. Polychlorinated biphenyls and methylmercury act synergistically to reduce rat brain dopamine content in vitro. Environ Health Perspect 107:879-885.
5. Bradford MM. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254.
6. Craft S, Asthana S, Newcomer JW, Wilkinson CW, Matos IT, Baker LD, Cherrier M, Lofgreen C, Latendresse S, Petrova A, Plymate S, Raskind M, Grimwood K, Veith RC. 1999. Enhancement of memory in Alzheimer disease with insulin and somatostatin, but not glucose. Arch Gen Psychiatry 56:1135-1140.
7. Darvill T, Lonky E, Reihman J, Stewart P, Pagano J. 2000. Prenatal exposure to PCBs and infant performance on the Fagan Test of infant intelligence. Neurotoxicology 21:1029-1038.
8. Duarte AI, Santos MS, Seica R, Oliveira CR. 2003. Insulin affects synaptosomal GABA and glutamate transport under oxidative stress conditions. Brain Res 977:23-30.
9. Frangiskakis JM, Ewart A, Morris C, Mervis C, Bertrand J, Robinson B, Klein BP, Ensing GJ, Everett LA, Green ED, Pröschel C, Gutowski NJ, Noble M, Atkinson DL, Odelberg SJ, Keating MT. 1996. LIM-kinase 1 hemizygosity implicated in impaired visuospatial conses structive cognition. Cell 86:59-69.
10. Fukazawa Y, Saitoh Y, Ozawa F, Ohta Y, Mizuno K, Inokuchi K. 2003. Hippocampal LTP is accompanied by enhanced F-actin content within the dendritic spine that is essential for late LTP maintenance in vivo. Neuron 38:447-460.
11. Gispen WH, Biessels GJ. 2000. Cognition and synaptic plasticity in diabetes mellitus. Trends Neurosci 23:542-549.
12. 2+ pool and of neuropeptide secretion. Nature 385:343-346.
13. Kanzaki M, Watson RT, Hou JC, Stamnes M, Saltiel AR, Pessin JE. 2002. Small GTP-binding protein TC10 differentially regulates two distinct populations of filamentous actin in 3T3L1 adipocytes. Mol Biol Cell 13:2334-2346.
14. Kern W, Peters A, Fruehwald-Schultes B, Deininger E, Born J, Fehm HL. 2001. Improving influence of insulin on cognitive functions in humans. Neuroendocrinology 74:270-280.
15. Kots AYa, Skurat AV, Sergienko EA, Bulargina TV, Severin ES. 1992. Nitroprusside stimulates the cysteine-specific mono (ADP-ribosylation) of glyceraldehyde-3-phosphate dehydrogenase from human erythrocytes. FEBS Lett 300:9-12.
16. Kuroda S, Tokunaga C, Kiyohara Y, Higuchi O, Konishi H, Mizuno K, Gill GN, Kikkawa U. 1996. Protein-protein interaction of zinc finger LIM domains with protein kinase C. J Biol Chem 271:31029-31032.
17. Malicka-Blaszkiewicz M. 1986. DNase-like activity and actin content in the liver of some vertebrates. Comp Biochem Physiol B 84:207-209.
18. Malicka-Blaszkiewicz M, Roth JS. 1981. Some factors affecting the interaction between actin in leukemia Ll210 cells and DNase I. Biochem Biophys Res Commun 102:594-601.
19. Meberg PJ, Ono S, Minamide LS, Takahashi M, Bamburg JR. 1998. Actin depolymerizing factor and cofilin phosphorylation dynamics: Response to signals that regulate neurite extension. Cell Motil Cytoskeleton 39:172-190.
20. Meng Y, Zhang Y, Tregoubov V, Janus C, Cruz L, Jackson M, Lu W-Y, MacDonald JF, Wang JY, Falls DL, Jia Z. 2002. Abnormal spine morphology and enhanced LTP in LIMK-1 knockout mice. Neuron 35:121-133.
21. Mitchison TJ, Cramer LP. 1996. Actin-based cell motility and cell locomotion. Cell 84:371-379.
22. Park CR, Seeley RJ, Craft S, Woods SC. 2000. Intracerebro-ventricular insulin enhances memory in a passive-avoidance task. Physiol Behav 68:509-514.
23. Shucard DW, Santa Maria MP, Specht CM, Podkulski M. 2003. Single-trial latency variability of auditory evoked potentials may indicate immediate memory in the albino rat. Int J Psychophysiol 47:229-241.
24. Smart FM, Halpain S. 2000. Regulation of dendritic spine stability. Hippocampus 10:542-554.
25. Tang F, Yan C, Wu S, Li F, Yu Y, Yu G, Jin X, Shen X. Polychlorinated biphenyls disrupt the actin cytoskeleton in hippocampal neurons. Environ Toxicol Pharmacol (in press).
26. Tojima T, Takahashi M, Ito E. 2003. Dual regulation of LIM kinase 1 expression by cyclic AMP and calcium determines cofilin phosphorylation states during neuritogenesis in NG108-15 cells. Brain Res 985:43-55.
27. Wang JY, Frenzel KE, Wen D, Falls DL. 1998. Transmembrane neuregulins interact with LIM kinase 1, a cytoplasmic protein kinase implicated in development of visuospatial cognition. J Biol Chem 273:20525-20534.
28. Widholm JJ, Clarkson GB, Strupp BJ, Crofton KM, Seegal RF, Schantz SL. 2001. Spatial reversal learning in Aroclor 1254-exposed rats: Sex-specific deficits in associative ability and inhibitory control. Toxicol Appl Pharmacol 174:188-198.
29. Willets JM, Nash MS, Challiss RA, Nahorski SR. 2004. Imaging of muscarinic acetylcholine receptor signaling in hippocampal neurons: Evidence for phosphorylation-dependent and -inde-pendent regulation by G-protein-coupled receptor kinases. J Neurosci 24:4157-4162.
30. Wysolmerski RB, Lagunoff D. 1988. Inhibition of endothelial cell retraction by ATP depletion. Am J Pathol 132:28-37.
31. Yang N, Higuchi O, Ohashi K, Nagata K, Wada A, Kangawa K, Nishida E, Mizuno K. 1998. Cofilin phosphorylation by LIM-kinase 1 and its role in Rac-mediated actin reorganization. Nature 393:809-812.
32. Zhao WQ, Alkon DL. 2001. Role of insulin and insulin receptor in learning and memory. Mol Cell Endocrinol 177(1/2):125-134.