Antioxidant Therapy in Idiopathic Tinnitus: Preliminary Outcomes

Archives of Medical Research

Volumn 38, Issue 4, 2007, Pages 456-459

  Savastano, Marina ^a   Brescia, Giuseppe ^a   Marioni, Gino ^a  

^a UNIVERSITY OF PADOVA   (Italy)

Author keywords

Antioxidant therapy; Idiopathic tinnitus; Reactive oxygen species

Indexed keywords

4 HYDROXYNONENAL; ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; BETA CAROTENE; GLYCEROPHOSPHOETHANOLAMINE; GLYCEROPHOSPHORYLCHOLINE; MALONALDEHYDE; REACTIVE OXYGEN METABOLITE;

ADULT; AGED; ARTICLE; AUDITORY THRESHOLD; CLINICAL ARTICLE; DRUG BLOOD LEVEL; FEMALE; HUMAN; LOUDNESS; MALE; OUTCOME ASSESSMENT; PURE TONE AUDIOMETRY; STATISTICAL SIGNIFICANCE; TINNITUS; VALIDITY; VISUAL ANALOG SCALE;

ADULT; AGED; ALDEHYDES; ANTIOXIDANTS; FEMALE; HUMANS; MALE; MALONDIALDEHYDE; MIDDLE AGED; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; TINNITUS; TREATMENT OUTCOME;

EID: 34047148495     PISSN: 01884409     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.arcmed.2006.12.004     Document Type: Article

References (30)

1. Gutteridge J.M.C. Free radicals in disease processes: a compilation of causes and consequences. Free Rad Res Commun 19 (1993) 141-158
2. Galli F., Piroddi M., Annetti C., Aisa C., Floridi E., and Floridi A. Oxidative stress and reactive oxygen species. Contrib Nephrol 149 (2005) 240-260
3. Shimosawa T. Increasing oxidative stress in aging. Nippon Rinsho 63 (2005) 994-999
4. Kang D., and Hamasaki N. Alterations of mitochondrial DNA in common diseases and disease states: aging, neurodegeneration, heart failure, diabetes and cancer. Curr Med Chem 12 (2005) 429-441
5. Signorelli S., Privitera G., Martini R., Di Pino L., Marraro S., and Neri S. Comportamento di alcuni parametri endoteliali (MDA) e coagulativi (Fibrinogeno e betatromboglobulina) in soggetti normali e arteriopatici. Min Angiol 17 (1992) 77
6. Cao W., Carney J.M., Douchon A., Floyd R.A., and Chevion M. Oxygen free radical involvement in ischemia and reperfusion injury in the brain. Neurosci Let 88 (1988) 233-238
7. Paravicini T.M., and Sobey C.G. Cerebral vascular effects of reactive oxygen species: recent evidence for a role of NADPH-oxidase. Clin Exp Pharmacol Physiol 30 (2003) 85-89
8. Rhyu D.Y., Yang Y., Ha H., Lee G.T., Song J.S., Uh S.T., et al. Role of reactive oxygen species in TGF-β1-induced mitogen-activated protein kinase activation and epithelial-mesenchymal transition in renal tubular epithelial cells. J Am Soc Nephrol 16 (2005) 667-675
9. Clerici W.J., and Yang L. Direct effects of intraperilymphatic reactive oxygen species generation on cochlear function. Hear Res 101 (1996) 14-22
10. Takumida M., Anniko M., and Popa R. Possible involvement of free radicals in lipopolysaccharide-induced labyrinthitis in the guinea pig: a morphological and functional investigation. ORL J Otorhinolaryngol Relat Spec 60 (1998) 246-253
11. Huang T., Cheng A.G., Stupak H., Liu W., Kim A., Staecker H., et al. Oxidative stress-induced apoptosis of cochlear sensory cells: otoprotective strategies. Int J Dev Neurosci 18 (2000) 258-270
12. Aubert A., Bernard C., Clauser P., Harpey C., and Vaudry H. A cellular anti-ischemic agent, trimetazidine prevents the deleterious effects of oxygen free-radicals on the internal ear. Ann Otalaryngol Clin Cervicofac 107 Suppl 1 (1990) 28-35
13. Neri S., Maceri B., Cilio D., Bordonaro F., Messina A., Malaguarnera M., et al. Tinnitus and oxidative stress in a selected series of elderly patients. Arch Gerontol Geriatr Suppl 8 (2002) 219-223
14. Bast A., Haenen G., and Doelman C. Oxidant and antioxidant: state of art. Am J Med 91 (1991) S2-S13
15. Yuen B., Furrer L., and Ballmer P.E. Antioxidant vitamin supplementation in the prevention of cardiovascular disease. Ther Umsch 62 (2005) 615-618
16. Fujisawa S., and Kadoma Y. Kinetic study of the radical-scavenging activity of vitamin E and ubiquinone. In Vivo 19 (2005) 1005-1011
17. Martinez-Sanchez G., Giuliani A., Perez-Davison G., and Leon-Fernandez O.S. Oxidized proteins and their contribution to redox homeostasis. Redox Rep 10 (2005) 175-185
18. Esterbauer H., and Cheeseman K.H. Determination of aldehydic lipid peroxidation products: malonaldehyde and 4-hydroxynoneal. Methods Enzymol 186 (1990) 407
19. Yagi K. Assay for serum lipid peroxide level and its chemical significance. In: Yagi K. (Ed). Lipid Peroxides in Biology and Medicine (1982), Academic Press, New York 223-242
20. Jackson M.J. Reactive oxygen species and redox-regulation of skeletal muscle adaptations to exercise. Philos Trans R Soc Lond Biol Sci 29 (2005) 2285-2291
21. Klebanoff S.J. Oxygen metabolites from phagocytes. In: Gallin J.I., Goldstein I.M., and Snyderman R. (Eds). Inflammation: basic principles and clinical correlates (1992), Raven Press, New York, NY
22. Huang M.F., Lin W.L., and Ma Y.C. A study of reactive oxygen species in mainstream of cigarette. Indoor Air 15 (2005) 135-140
23. Krikun G., Critchley H., Schatz F., Wan L., Caze R., Baergen R.N., and Lockwood C.J. Abnormal uterine bleeding during progestin-only contraception may result from free radical-induced alterations in angiopoietin expression. Am J Pathol 161 (2002) 979-986
24. Powers S.K., and Lennon S.L. Analysis of cellular responses to free radicals: focus on exercise and skeletal muscle. Proc Nutr Soc 58 (1999) 1025-1033
25. Vane J.R., Anggard E., and Botting R.M. Regulatory functions of the vascular endothelium. N Engl J Med 323 (1990) 27-36
26. De Keulenaer G.W., Andries L.J., Sys S.U., and Brutsaert D.L. Endothelin-mediated positive inotropic effect induced by reactive oxygen species in isolated cardiac muscle. Circ Res 76 (1995) 878-884
27. Lehr H.A., Frei B., Olofsson A.M., Carew T.E., and Arfors K.E. Protection from oxidized LDL-induced leukocyte adhesion to microvascular and macrovascular endothelium in vivo by vitamin C but not by vitamin E. Circulation 91 (1995) 1525-1532
28. Davies K.J. Protein damage and degradation by oxygen radicals. General aspects. J Biol Chem 262 (1987) 95-98
29. Amer J., Goldfarb A., and Fibach E. Flow cytometric analysis of the oxidative status of normal and thalassemic red blood cells. Cytometry A 60 (2004) 73-80
30. Ewing J.A. Detecting alcoholism: the CAGE questionnaire. JAMA 252 (1984) 1905-1907