Effect of melatonin on healing of colonic anastomosis in a rat model of peritonitis

European Surgical Research

Volumn 39, Issue 2, 2007, Pages 122-127

  Ozen I O ^a,c   Ekingen, G ^b   Taslipinar M Y ^a   Bukan, N ^a   Demirogullari B ^a   Karabulut, R ^a   Sonmez K ^a   Basaklar A C ^a   Kale, N ^a  

^a GAZI UNIVERSITY   (Turkey)

^b KOCAELI UNIVERSITY   (Turkey)

^c GAZI UNIVERSITY FACULTY OF MEDICINE   (Turkey)

Author keywords

Anastomotic healing; Bursting pressure; Glutathione; Interleukin 6; Melatonin; Peritonitis; Tissue malondialdehyde; Tumor necrosis factor

Indexed keywords

GLUTATHIONE; INTERLEUKIN 6; MALONALDEHYDE; MELATONIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL PERITONITIS; CECUM; COLON ANASTOMOSIS; CONTROLLED STUDY; DRUG EFFECT; GASTROINTESTINAL SURGERY; LAPAROTOMY; LIGATION; NONHUMAN; PRIORITY JOURNAL; RAT; REOPERATION; SECOND LOOK SURGERY; WISTAR RAT; WOUND HEALING;

ANASTOMOSIS, SURGICAL; ANIMALS; ANTIOXIDANTS; COLON; DISEASE MODELS, ANIMAL; GLUTATHIONE; INTERLEUKIN-6; MALONDIALDEHYDE; MELATONIN; PERITONITIS; RATS; RATS, WISTAR; TUMOR NECROSIS FACTOR-ALPHA; WOUND HEALING;

EID: 34047143291     PISSN: 0014312X     EISSN: None     Source Type: Journal    
DOI: 10.1159/000100068     Document Type: Article

References (30)

1. Vaneerdeweg W, Hendriks JMH, Lauwers PRM, Ieven M, Eyskens EJM: Effects of gentamicin-containing sponges on the healing of colonic anastomoses in a rat model of peritonitis. Eur J Sur 2000;166:959-962.
2. Sakall?oglu AE, Yagmurlu A, Dindar H, Has?rc? N, Renda N, Deveci MS: Sustained local application of low-dose epidermal growth factor on steroid-inhibited colonic wound healing. J Pediatr Surg 2004;39:591-595.
3. Khalili TM, Navarro RA, Middleton Y, Margulies DR: Early postoperative enteral feeding increases anastomotic strength in a peritonitis model. Am J Surg 2001;182:621-624.
4. Reijnen MMPJ, de Man BM, Hendriks Th, Postma VA, Meis JFGM, van Goor H: Hyaluronic acid-based agents do not affect anastomotic strength in rat colon, in either the presence or absence of bacterial peritonitis. Br J Surg 2000;87:1222-1228.
5. Hubbard WJ, Choudhry M, Schawacha MG, Kerby JD, Rue LW 3rd, Bland KI, Chaudry IH: Cecal ligation and puncture. Shock 2005;24:52-57.
6. Remick DG, Bolgos G, Copeland S, Siddiqui J: Role of IL-6 in mortality from and physiologic response to sepsis. Infect Immun 2005;73:2751-2757.
7. Srinivasan V, Maestruni GJM, Esquifino AI, Pandi Perumal SR, Miller SC: Melatonin, immune function and aging. Immun Ageing 2005;2:1-10.
8. Soybir G, Topuzlu C, Odabaş Ö, Dolay K, Bilir A, Köksoy F: The effects of melatonin on angiogenesis and wound healing. Surg Today 2003;33:896-901.
9. Reynolds FD, Dauchy R, Dietz PA, Lynch D, Zuckerman R: The pineal gland hormone melatonin improves survival in a rat model of sepsis/shock induced by zymosan A. Surgery 2003;134:474-479.
10. Paskaloǧlu K, Şener G, Kapucu C, Ayanoǧlu- Dülger G: Melatonin treatment protects against sepsis-induced functional and biochemical changes in rat ileum and urinary bladder. Life Sci 2004;74:1093-1104.
11. Şener G, Toklu H, Ercan F, Erkanli G: Protective effect of β-glucagon against oxidative organ injury in a rat model of sepsis. Int Immunopharmacol 2005;1387-1396.
12. Basak PY, Aǧalar F, Gültekin F, Eroǧlu E, Altuntaş İ, Aǧalar C: The effect of thermal injury and melatonin on incisional wound healing. Ulus Travma Acil Cerrahi Derg 2003;9:96-101.
13. Wichterman KA, Baue AE, Chaudry IH: Sepsis and septic shock: a review of laboratory models and a proposal. J Surg Res 1980;29:189-201.
14. Aszodi A, Ponsky JL: Effects of 5-fluorouracil on healing of bowel anastomosis in rats. Am Surg 1985;51:671-674.
15. Demiroǧullar? B, Sönmez K, Türky?lmaz Z, Ekingen G, Dursun A, Bor V, Türközkan N, Başaklar C, Kale K: Compression of consequent small bowel anastomoses after transient ischemia: an experimental study in rats. J Pediatr Surg 1998;33:91-93.
16. Mihara M, Uchiyama M: Determination of malonaldehyde precursor in tissue by thiobarbituric acid test. Ann Biochem 1978;86:271-278.
17. Ellman GL: Tissue sulfhydryl groups. Arch Biochem Biophys 1959;82:70-77.
18. Ishumura K, Moroguchi A, Okano K, Maeba T, Maeta H: Local expression of tumor necrosis factor-α and interleukin-10 on wound healing of intestinal anastomosis during endotoxemia in mice. J Surg Res 2002;108:91-97.
19. Feilding LP, Stewart-Brown S, Blesovsky L, Kearny G: Anastomotic integrity after operation for large-bowel cancer: a multicentre study. BMJ 1980;281:411.
20. Gitto E, Karbownik M, Reiter RJ, Tan DX, Cuzzocrea S, Chiurazzi P, Cordaro S, Corona, G, Trimarchi G, Barberi I: Effects of melatonin treatment in septic newborns. Pediatric Res 2001;50:756-760.
21. Riche FC, Cholley BP, Panis YH, Laisne MJ, Briard CG, Graulet AM, Gueris JL, Valleur PD: Inflammatory cytokine response in patients with septic shock secondary to generalized peritonitis. Crit Care Med 2000;28:433-437.
22. Kettle AJ, Winterbourn C: Myeloperoxidase: a key regulator of neutrophil oxidant production. Redox Rep 1997;3:3-15.
23. Macdonald J, Galley HF, Webster NR: Oxidative stress and gene expression in sepsis. Br J Anaesth 2003;90:221-232.
24. Gitto E, Romeo C, Reiter RJ, Impellizzeri P, Pesce S, Basile M, Antonuccio P, Rrimarchi G, Gentile C, Barberi I, Zuccarello B: Melatonin reduces oxidative stress in surgical neonates. J Pediatr Surg 2004;39:184-189.
25. Bulbuller N, Dogru O, Yekeler H, Cetinkaya Z, Ilhan N, Kirkil C: Effect of melatonin on wound healing in normal and pinealectomized rats. J Surg Res 2005;123:3-7.
26. Ozdogan M, Oruk I, Renda N, Kaynaroglu V, Baykal A: The effect of exogenous melatonin on experimental colonic anastomosis. Acta Chir Belg 2005;105:302-305.
27. Reither RJ, Tan DX, Osuna C, Gitto E: Actions of melatonin in the reduction of oxidative stress. A review. J Biomed Sci 2000;7:444-458.
28. Reiter RJ, Calvo RJ, Karbownik MQW, Tan DX: Melatonin and its relation to the immune system and inflammation. Ann NY Acad Sci 2000;917:376-386.
29. Reiter RJ, Tan DX, Gitto E, Sainz RM, Mayo JC, Leon J, Manchester LC, Vijayalaxmi, Kilic E, Kilic U: Pharmacological utility of melatonin in reducing oxidative cellular and molecular damage. Pol J Pharmacol 2004;56:159-170.
30. Carossino AM, Lombardi A, Matucci-Cerinic M, Pignone A, Cagnoni M: Effect of melatonin on normal and sclerodermic skin fibroblast proliferation. Clin Exp Rheumatol 1996;14:493-498.