Cambridge Healthtech Institute's 7th Annual, Identifying and Validating Metabolic Markers for Drug Development and Clinical Studies: 4-6 December, 2006, Orlando, FL, USA

Expert Review of Molecular Diagnostics

Volumn 7, Issue 2, 2007, Pages 113-115

  Beger, Richard D ^a  

^a NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; SORAFENIB;

BIOINFORMATICS; CANCER RESEARCH; CLINICAL RESEARCH; CLINICAL TRIAL; CONFERENCE PAPER; DRUG CYTOTOXICITY; DRUG RESEARCH; DRUG SCREENING; GENOMICS; HEALTH CARE ORGANIZATION; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; ION MOBILITY SPECTROMETRY; KIDNEY CARCINOMA; LIQUID CHROMATOGRAPHY; MEDICAL INFORMATICS; METABOLIC DISORDER; METABOLOMICS; MOLECULAR DYNAMICS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PHARMACOGENOMICS; PROTEOMICS; UNITED STATES;

ANIMALS; BIOLOGICAL MARKERS; DRUG DESIGN; HUMANS; PHARMACEUTICAL PREPARATIONS;

EID: 34047131650     PISSN: 14737159     EISSN: 17448352     Source Type: Journal    
DOI: 10.1586/14737159.7.2.113     Document Type: Conference Paper

References (8)

1. Tweeddale H, Notley-McRobb L, Ferenci T. Effect of slow growth on metabolism of Escherichia coli, as revealed by global metabolite pool ("metabolome") analysis. J. Bacteriol. 180, 5109-5116 (1998).
2. Nicholson JK, Lindon JC, Holmes E. 'Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data. Xenobiotica 29, 1181-1189 (1999).
3. Trujillo E, Davis C, Milner J. Nutrigenomics, proteomics, metabolomics and the practice of dietetics. J. Am. Diet Assoc. 106, 403-413 (2006).
4. Kochhar S, Jacobs DM, Ramadan Z, Berruex F, Fuerholz A, Fay LB. Probing gender-specific metabolism differences in humans by nuclear magnetic resonance-based metabonomics. Anal. Biochem. 352, 274-281 (2006).
5. Serkova N, Fuller TF, Klawitter J, Freise CE, Niemann CU. H-NMR-based metabolic signatures of mild and severe ischemia/reperfusion injury in rat kidney transplants. Kidney Int. 67, 1142-1151 (2005).
6. Wishart DS, Tzur D, Knox C et al. HMDB: the Human Metabolome Database. Nucleic Acids Res. 35, D521-D526 (2007).
7. National Institutes of Health www.nih.gov
8. US FDA: The Critical Path to New Medical Products www.fda.gov/oc/ initiatives/criticalpath