Effect of hyaluronic acid and polysaccharides from Opuntia ficus indica (L.) cladodes on the metabolism of human chondrocyte cultures

Journal of Ethnopharmacology

Volumn 111, Issue 2, 2007, Pages 315-321

  Panico, A M ^a   Cardile, V ^a   Garufi, F ^a   Puglia, C ^a   Bonina, F ^a   Ronsisvalle, S ^a  

^a UNIVERSITY OF CATANIA   (Italy)

Author keywords

Chondrocytes; Glycosaminoglycans; Hyaluronic acid; Interleukin 1 ; Nitric oxide; Opuntia ficus indica (L.); Prostaglandins; Reactive oxygen species

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; ANTIINFLAMMATORY AGENT; GLYCOSAMINOGLYCAN; HYALURONIC ACID; INTERLEUKIN 1BETA; NITRIC OXIDE; OPUNTIA FICUS INDICA EXTRACT; PLANT EXTRACT; POLYPHENOL DERIVATIVE; POLYSACCHARIDE; PROSTAGLANDIN; REACTIVE OXYGEN METABOLITE; TOCOPHEROL; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CARTILAGE CELL; CELL CULTURE; CHONDROPROTECTION; CONTROLLED STUDY; DRUG MECHANISM; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; INFLAMMATION; OPUNTIA FICUS INDICA; PLANT;

ANTI-INFLAMMATORY AGENTS; ANTIOXIDANTS; CARTILAGE, ARTICULAR; CELL CULTURE TECHNIQUES; CELL SURVIVAL; CELLS, CULTURED; CHONDROCYTES; CULTURE MEDIA, CONDITIONED; DINOPROSTONE; DRUG EVALUATION, PRECLINICAL; FEMORAL NECK FRACTURES; GLYCOSAMINOGLYCANS; HUMANS; HYALURONIC ACID; NITRITES; OPUNTIA; PLANT EXTRACTS; PLANT STEMS; POLYSACCHARIDES; REACTIVE OXYGEN SPECIES; SPECTROPHOTOMETRY;

OPUNTIA FICUS-INDICA;

EID: 34047130316     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2006.11.020     Document Type: Article

References (21)

1. Bedi M.K., and Shenefelt P.D. Herbal therapy in dermatology. Arch. Dermatol. 138 (2002) 232-242
2. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72 (1976) 248-254
3. El Kossori R.L., Villaume C., El Boustani E., Sauvaire Y., and Mejean L. Composition of pulp, skin and seeds of prickly pears fruit (Opuntia ficus indica sp.). Plant Foods Hum. Nutr. 52 (1998) 263-270
4. Farndale R.W., Sayers C.A., and Barrett A.J. A direct spectrophotometric microassay for sulphated glycosaminoglycans in cultured cartilage. Connect. Tissue Res. 2 (1989) 247-248
5. Flugge L.A., Miller-Deist L.A., and Petillo P.A. Towards a molecular understanding of arthritis. Chem. Biol. 6 (1999) 157-166
6. Gaby A.R. Natural treatments for osteoarthritis. Altern. Med. Rev. 4 (1999) 330-341
7. Galati E.M., Tripodo M.M., Trovato A., Miceli N., and Manforte M.T. Biological effect of Opuntia ficus indica (L.) Mill. (Cactaceae) waste matter. Note I: Diuretic activity. J. Ethnopharmacol. 79 (2002) 17-21
8. 15N] nitrate in biological fluids. Anal. Biochem. 126 (1982) 131-138
9. Kuti J.O. Antioxidant compounds from four Opuntia cactus pear fruit varieties. Food Chem. 85 (2004) 527-533
10. Lee J.C., Kim H.R., Kim J., and Jang Y.S. Antioxidant property of an ethanol extract of the stem of Opuntia ficus indica var. saboten. J. Agric. Food Chem. 50 (2002) 6490-6496
11. Manfield L., Jang D., and Murrel G.A. Nitric oxide enhances cyclooxygenase activity in articular cartilage. Inflamm. Res. 45 (2000) 254-258
12. Mankarios A.T., Jones C.F.G., Jarvis M.C., Thelfall D.R., and Friend J. Hydrolysis of plant polysaccharides and GLC analysis of their constituent neutral sugars. Phytochemistry 18 (1979) 419-422
13. McGarvie D., and Parolis H. Methylation analysis of the mucilage of Opuntia ficus indica. Carbohydr. Res. 88 (1981) 305-314
14. Mossmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods 65 (1983) 55-63
15. Panico A.M., Cardile V., Garufi F., Puglia C., Bonina F., and Ronsisvalle G. Protective effects of Capparis spinosa on chondrocytes. Life Sci. 77 (2005) 2479-2488
16. Park E.H., and Chun M.J. Wound healing of Opuntia ficus indica. Fitoterapia 72 (2001) 165-167
17. Renis M., Cardile V., Palumbo M., and Russo A. Et-18-OCH3-induced cytotoxicity and DNA damage in rat astrocytes. Int. J. Dev. Neurosci. 18 (2000) 545-555
18. Schaffer C.J., and Nanney L.B. Cell biology of wound healing. Int. Rev. Cytol. 169 (1996) 151-181
19. Shin H.C., Hwang H.J., Kang K.J., and Lee B.H. An antioxidative and antiinflammatory agent for potential treatment of osteoarthritis from Ecklonia cava. Arch. Pharm. Res. 29 (2006) 165-171
20. Sorrenti V., Salerno L., Di Giacomo C., Acquaviva R., Siracusa M.A., and Vanella A. Imidazole derivatives as antioxidants and selective inhibitors of nNOS. Nitric Oxide 14 (2006) 45-50
21. Trombetta D., Puglia C., Perri D., Licata A., Pergolizzi S., Lauriano E.R., De Pasquale A., Sajia A., and Bonina F.P. Effect of polysaccharides from Opuntia ficus indica (L.) cladodes on the healing of dermal wounds in the rat. Phytomedicine 13 (2006) 352-358