Pregnancy-associated plasma protein-A: An emerging cardiac biomarker

International Journal of Cardiology

Volumn 117, Issue 3, 2007, Pages 370-372

  Thorn, Eric M ^a   Khan, Ijaz A ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

Acute coronary syndrome; Atherosclerosis; Cardiac biomarkers; Pregnancy associated plasma protein A

Indexed keywords

BIOLOGICAL MARKER; METALLOPROTEINASE; PREGNANCY ASSOCIATED PLASMA PROTEIN A; SOMATOMEDIN C;

ACUTE CORONARY SYNDROME; ATHEROGENESIS; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; DIAGNOSTIC VALUE; DISEASE MARKER; EDITORIAL; ENDOTHELIUM CELL; FIBROBLAST; HUMAN; PRIORITY JOURNAL; VASCULAR SMOOTH MUSCLE;

ACUTE DISEASE; ANGINA, UNSTABLE; BIOLOGICAL MARKERS; CORONARY ARTERIOSCLEROSIS; HUMANS; MYOCARDIAL INFARCTION; PREGNANCY-ASSOCIATED PLASMA PROTEIN-A; SYNDROME;

EID: 33947724733     PISSN: 01675273     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijcard.2006.11.001     Document Type: Editorial

References (14)

1. Alpert J.S., Thygesen K., Antman E., and Bassand J.P. Myocardial infarction redefined: a consensus document of The Joint European Society of Cardiology/American College of Cardiology Committee for the redefinition of myocardial infarction. J Am Coll Cardiol 36 (2000) 959-969
2. Galvani M., Ottani F., Ferrini D., et al. Prognostic influence of elevated values of cardiac troponin I in patients with unstable angina. Circulation 95 (1997) 2053-2059
3. Lin T.M., Galbert S.P., Kiefer D., Spellacy W.N., and Gall S. Characterization of four human pregnancy-associated plasma proteins. Am J Obstet Gynecol 118 (1974) 223-236
4. Bonno M., Oxvig C., Kephart G.M., et al. Localization of pregnancy-associated plasma protein-A and colocalization of pregnancy-associated plasma protein-A messenger ribonucleic acid and eosinophil granule major basic protein messenger ribonucleic acid in placenta. Lab Invest 71 (1994) 560-566
5. Lawrence J.B., Oxvig C., Overgaard M.T., et al. The insulin-like growth factor (IGF)-dependent IGF binding protein-4 protease secreted by human fibroblasts is pregnancy-associated plasma protein-A. Proc Natl Acad Sci U S A 96 (1999) 3149-3153
6. Bayes-Genis A., Conover C.A., and Schwartz R.S. The insulin-like growth factor axis: a review of atherosclerosis and restenosis. Circ Res 86 (2000) 125-130
7. Bayes-Genis A., Conover C.A., Overgaard M.T., et al. Pregnancy-associated plasma protein A as a marker of acute coronary syndromes. N Engl J Med 345 (2001) 1022-1029
8. Bayes-Genis A., Schwartz R.S., Lewis D.A., et al. Insulin-like growth factor binding protein-4 protease produced by smooth muscle cells increases in the coronary artery after angioplasty. Arterioscler Thromb Vasc Biol 21 (2001) 335-341
9. Sangiorgi G., Mauriello A., Bonanno E., et al. Pregnancy-associated plasma protein-a is markedly expressed by monocyte-macrophage cells in vulnerable and ruptured carotid atherosclerotic plaques: a link between inflammation and cerebrovascular events. J Am Coll Cardiol 47 (2006) 2201-2211
10. Lund J., Qin Q.P., Ilva T., et al. Circulating pregnancy-associated plasma protein a predicts outcome in patients with acute coronary syndrome but no troponin I elevation. Circulation 108 (2003) 1924-1926
11. Laterza O.F., Cameron S.J., Chappell D., Sokoll L.J., and Green G.B. Evaluation of pregnancy-associated plasma protein A as a prognostic indicator in acute coronary syndrome patients. Clin Chim Acta 348 (2004) 163-169
12. Khosravi J., Diamandi A., Krishna R.G., Bodani U., Mistry J., and Khaja N. Pregnancy associated plasma protein-A: ultrasensitive immunoassay and determination in coronary heart disease. Clin Biochem 35 (2002) 531-538
13. Qin Q.P., Laitinen P., Majamaa-Voltti K., Eriksson S., Kumpula E.K., and Pettersson K. Release patterns of pregnancy associated plasma protein A (PAPP-A) in patients with acute coronary syndromes. Scand Cardiovasc J 36 (2002) 358-361
14. Heeschen C., Dimmeler S., Hamm C.W., Fichtlscherer S., Simoons M.L., and Zeiher A.M. Pregnancy-associated plasma protein-A levels in patients with acute coronary syndromes: comparison with markers of systemic inflammation, platelet activation, and myocardial necrosis. J Am Coll Cardiol 45 (2005) 229-237