Investigation of in vivo measurement of cerebral cytochrome-c-oxidase redox changes using near-infrared spectroscopy in patients with orthostatic hypotension

Physiological Measurement

Volumn 28, Issue 2, 2007, Pages 199-211

  Tachtsidis, I ^a   Tisdall, M ^b   Leung, T S ^a   Cooper, C E ^c   Delpy, D T ^a   Smith, M ^b   Elwell, C E ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b NATIONAL HOSPITAL FOR NEUROLOGY AND NEUROSURGERY   (United Kingdom)

^c UNIVERSITY OF ESSEX   (United Kingdom)

Author keywords

Autonomic failure; Cerebral cytochrome c oxidase; Cerebral oxygenation; Near infrared spectroscopy

Indexed keywords

BLOOD PRESSURE; INFRARED DEVICES; SPECTROMETERS;

% REDUCTIONS; AUTONOMIC FAILURE; AUTONOMICS; CEREBRAL CYTOCHROME-C-OXIDASE; CEREBRAL OXYGENATION; CYTOCHROME-C OXIDASE; HAEMOGLOBINS; HEAD-UP TILTS; IN-VIVO MEASUREMENT; OXIDIZED CYTOCHROME;

NEAR INFRARED SPECTROSCOPY;

CYTOCHROME C OXIDASE; DEOXYHEMOGLOBIN; OXYHEMOGLOBIN; HEMOGLOBIN;

ADULT; AGED; ARTICLE; AUTONOMIC DYSFUNCTION; CALCULATION; CLINICAL ARTICLE; CONCENTRATION (PARAMETERS); FEMALE; HEAD TILTING; HEMOGLOBIN DETERMINATION; HUMAN; MALE; MEAN ARTERIAL PRESSURE; NEAR INFRARED SPECTROSCOPY; ORTHOSTATIC HYPOTENSION; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; SPECTRAL SENSITIVITY; SUPINE POSITION; ALGORITHM; BLOOD PRESSURE; BRAIN; CHEMISTRY; ENZYMOLOGY; METABOLISM; MIDDLE AGED; PHYSIOLOGY; STATISTICAL ANALYSIS;

ADULT; AGED; ALGORITHMS; BLOOD PRESSURE; BRAIN; DATA INTERPRETATION, STATISTICAL; ELECTRON TRANSPORT COMPLEX IV; FEMALE; HEMOGLOBINS; HUMANS; HYPOTENSION, ORTHOSTATIC; MALE; MIDDLE AGED; OXIDATION-REDUCTION; OXYHEMOGLOBINS; SPECTROSCOPY, NEAR-INFRARED; SUPINE POSITION;

EID: 33947722933     PISSN: 09673334     EISSN: 13616579     Source Type: Journal    
DOI: 10.1088/0967-3334/28/2/008     Document Type: Article

References (42)

1. Beinert H, Shaw R W, Hansen R E and Hartzell C R 1980 Studies on the origin of the near-infrared (800-900 nm) absorption of cytochrome c oxidase Biochim. Biophys. Acta. 591 458-70
2. Colier W N, Binkhorst R A, Hopman M T and Oeseburg B 1997 Cerebral and circulatory haemodynamics before vasovagal syncope induced by orthostatic stress Clin. Physiol. 17 83-94
3. Cooper C, Sharpe M, Elwell C, Springett R, Penrice J, Tyszczuk L, Amess P, Wyatt J, Quaresima V and Delpy D 1997a The cytochrome oxidase redox state in vivo Adv. Exp. Med. Biol. 428 449-56
4. Cooper C E, Cope M, Springett R, Amess P N, Penrice J, Tyszczuk L, Punwani S, Ordidge R, Wyatt J and Delpy D T 1999 Use of mitochondrial inhibitors to demonstrate that cytochrome oxidase near-infrared spectroscopy can measure mitochondrial dysfunction noninvasively in the brain J. Cereb. Blood Flow Metab. 19 27-38
5. Cooper C E, Delpy D T and Nemoto E M 1998 The relationship of oxygen delivery to absolute haemoglobin oxygenation and mitochondrial cytochrome oxidase redox state in the adult brain: a near-infrared spectroscopy study Biochem. J. 332 627-32
6. Cooper C E et al 1997b Measurement of cytochrome oxidase redox state by near infrared spectroscopy Adv. Exp. Med. Biol. 413 63-73
7. Cooper C E, Matcher S J, Wyatt J S, Cope M, Brown G C, Nemoto E M and Delpy D T 1994 Near-infrared spectroscopy of the brain: relevance to cytochrome oxidase bioenergetics Biochem. Soc. Trans. 22 974-80
8. Cope M 1991 The development of a near infrared spectroscopy system and its application for non-invasive monitoring of cerebral blood and tissue oxygenation in the newborn infant PhD Thesis University of London
9. Delpy D T, Cope M, van der Zee P, Arridge S, Wray S and Wyatt J 1988 Estimation of optical pathlength through tissue from direct time of flight measurement Phys. Med. Biol. 33 1433-42
10. Drabkin D L 1951 Metabolism of the hemin chromoproteins Physiol. Rev. 31 345-431
11. Duncan A, Meek J H, Clemence M, Elwell C E, Fallon P, Tyszczuk L, Cope M and Delpy D T 1996 Measurement of cranial optical path length as a function of age using phase resolved near infrared spectroscopy Pediatr. Res. 39 889-94
12. Edwards A D, Brown G C, Cope M, Wyatt J S, McCormick D C, Roth S C, Delpy D T and Reynolds E O 1991 Quantification of concentration changes in neonatal human cerebral oxidized cytochrome oxidase J. Appl. Physiol. 71 1907-13
13. Essenpreis M, Elwell C E, Cope M, van der Zee P, Arridge S R and Delpy D T 1993 Spectral dependence of temporal point spread functions in human tissues Appl. Opt. 32 418-25
14. Harms M P, Colier W N, Wieling W, Lenders J W, Secher N H and van Lieshout J J 2000 Orthostatic tolerance, cerebral oxygenation, and blood velocity in humans with sympathetic failure Stroke 31 1608-14
15. Hesse B, Mehlsen J, Boesen F, Schmidt J F, Andersen E B, Waldemar G, Andersen A R, Paulson O B and Vorstrup S 2002 Regulation of cerebral blood flow in patients with autonomic dysfunction and severe postural hypotension Clin. Physiol. Funct. Imaging 22 241-7
16. Hetzel A, Reinhard M, Guschlbauer B and Braune S 2003 Challenging cerebral autoregulation in patients with preganglionic autonomic failure Clin. Auton. Res. 13 27-35
17. Hunt K, Tachtsidis I, Bleasdale-Barr K, Elwell C, Mathias C J and Smith M 2006 Changes in cerebral oxygenation and haemodynamics during postural blood pressure changes in patients with autonomic failure Physiol. Meas. 27 777-85
18. Jöbsis F F 1977 Noninvasive, infrared monitoring of cerebral and myocardial oxygen sufficiency and circulatory parameters Science 198 1264-7
19. Jöbsis F F, Keizer J H, LaManna J C and Rosenthal M 1977 Reflectance spectrophotometry of cytochrome aa3 in vivo J. Appl. Physiol. 43 858-72
20. Kakihana Y, Matsunaga A, Tobo K, Isowaki S, Kawakami M, Tsuneyoshi I, Kanmura Y and Tamura M 2002 Redox behavior of cytochrome oxidase and neurological prognosis in 66 patients who underwent thoracic aortic surgery Eur. J. Cardiothorac. Surg. 21 434-9
21. Kirkpatrick P J, Lam J, Al-Rawi P, Smielewski P and Czosnyka M 1998 Defining thresholds for critical ischemia by using near-infrared spectroscopy in the adult brain J. Neurosurg. 89 389-94
22. Lye M and Walley T 1998 Haemodynamic responses in young and elderly, healthy subjects during ambient and warm head-up tilt Clin. Sci. (Lond.) 94 493-8
23. Madsen P, Pott F, Olsen S B, Nielsen H B, Burcev I and Secher N H 1998 Near-infrared spectrophotometry determined brain oxygenation during fainting Acta. Physiol. Scand. 162 501-7
24. Matcher S J, Elwell C E, Cooper C E, Cope M and Delpy D T 1995 Performance comparison of several published tissue near-infrared spectroscopy algorithms Anal. Biochem. 227 54-68
25. Mathias C J 2003 Autonomic diseases-clinical features and laboratory evaluation J. Neurol. Neurosurg. Psychiatry 74 31-41
26. Mathias C J, Mallipeddi R and Bleasdale-Barr K 1999 Symptoms associated with orthostatic hypotension in pure autonomic failure and multiple system atrophy J. Neurol. 246 893-8
27. Matsunaga A, Nomura Y, Kuroda S, Tamura M, Nishihira J and Yoshimura N 1998 Energy-dependent redox state of heme a + a3 and copper of cytochrome oxidase in perfused rat brain in situ Am. J. Physiol. 275 C1022-C1030
28. McGown A D, Makker H, Elwell C, Al Rawi P G, Valipour A and Spiro S G 2003 Measurement of changes in cytochrome oxidase redox state during obstructive sleep apnea using near-infrared spectroscopy Sleep 26 710-6
29. Nollert G, Mohnle P, Tassani-Prell P, Uttner I, Borasio G D, Schmoeckel M and Reichart B 1995 Postoperative neuropsychological dysfunction and cerebral oxygenation during cardiac surgery Thorac. Cardiovasc. Surg. 43 260-4
30. Nollert G, Shin'oka T and Jonas R A 1998 Near-infrared spectrophotometry of the brain in cardiovascular surgery Thorac. Cardiovasc. Surg. 46 167-75
31. Novak V, Novak P, Spies J M and Low P A 1998 Autoregulation of cerebral blood flow in orthostatic hypotension Stroke 29 104-11
32. Quaresima V, Springett R, Cope M, Wyatt J T, Delpy D T, Ferrari M and Cooper C E 1998 Oxidation and reduction of cytochrome oxidase in the neonatal brain observed by in vivo near-infrared spectroscopy Biochim. Biophys. Acta. 1366 291-300
33. Richter O M and Ludwig B 2003 Cytochrome c oxidase-structure, function, and physiology of a redox-driven molecular machine Rev. Physiol. Biochem. Pharmacol. 147 47-74
34. Schondorf R, Benoit J and Stein R 2001a Cerebral autoregulation in orthostatic intolerance Ann. N Y Acad. Sci. 940 514-26
35. Schondorf R, Stein R, Roberts R, Benoit J and Cupples W 2001b Dynamic cerebral autoregulation is preserved in neurally mediated syncope J. Appl. Physiol. 91 2493-502
36. Skov L and Greisen G 1994 Apparent cerebral cytochrome aa3 reduction during cardiopulmonary bypass in hypoxaemic children with congenital heart disease. A critical analysis of in vivo near-infrared spectrophotometric data Physiol. Meas. 15 447-57
37. Springett R, Newman J, Cope M and Delpy D T 2000 Oxygen dependency and precision of cytochrome oxidase signal from full spectral NIRS of the piglet brain Am. J. Physiol. Heart Circ. Physiol. 279 H2202-H2209
38. Springett R J, Wylezinska M, Cady E B, Hollis V, Cope M and Delpy D T 2003 The oxygen dependency of cerebral oxidative metabolism in the newborn piglet studied with 31P NMRS and NIRS Adv. Exp. Med. Biol. 530 555-63
39. Tachtsidis I, Cooper C E, McGown A D, Makker H, Delpy D T and Elwell C E 2004 Changes in cerebral total haemoglobin volume and cytochrome oxidase redox state during deep apnoeas in patients with obstructive sleep apnoea Biomedical Topical Meetings on CD-ROM (The Optical Society of America, Washington, DC) WF6
40. Tsuji M, Naruse H, Volpe J and Holtzman D 1995 Reduction of cytochrome aa3 measured by near-infrared spectroscopy predicts cerebral energy loss in hypoxic piglets Pediatr. Res. 37 253-9
41. Uludag K, Steinbrink J, Kohl-Bareis M, Wenzel R, Villringer A and Obrig H 2004 Cytochrome-c-oxidase redox changes during visual stimulation measured by near-infrared spectroscopy cannot be explained by a mere crosstalk artefact Neuroimage 22 109-19
42. van Lieshout J J, Wieling W, Karemaker J M and Secher N H 2003 Syncope, cerebral perfusion, and oxygenation J. Appl. Physiol. 94 833-48