Asymmetric synthesis of novel α-amino acids with β-branched side chains

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 9, 2007, Pages 2401-2403

  Zhang, Minsheng ^a   Porte, Alex ^a   Diamantidis, George ^a   Sogi, Kimberly ^a   Kubrak, Dennis ^a   Resnick, Lynn ^a   Mayer, Scott C ^a   Wang, Zheng ^a   Kreft, Anthony F ^a   Harrison, Boyd L ^a  

^a PFIZER INC   (United States)

Author keywords

Amino acids; Asymmetric synthesis

Indexed keywords

4 TOLUENESULFINYLIMINE; ALPHA AMINO ACID; IMINE; TOLUENE DERIVATIVE; UNCLASSIFIED DRUG;

AMINO ACID SYNTHESIS; ARTICLE; ASYMMETRIC SYNTHESIS; CHIRALITY; PHARMACOPHORE; REACTION ANALYSIS; STEREOCHEMISTRY; STRECKER SYNTHESIS; STRUCTURE ANALYSIS;

AMINO ACIDS; CHEMISTRY, ORGANIC; CHEMISTRY, PHARMACEUTICAL; DRUG DESIGN; MODELS, CHEMICAL; MOLECULAR CONFORMATION;

EID: 33947722688     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.02.041     Document Type: Article

References (7)

1. Kreft, A.F.; Resnick, L.; Mayer, S.C.; Diamantidis, G.; Cole, D.C.; Harrison, B.L.; Zhang, M.; Hoke, M.; Ting, W.; Galante, R.C.U.S. Patent 20040198778, 2004.
2. Chem. Abstr. 141 (2004) 314147
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4. 4-6
5. 2), 3.6 (1H, 2t, CHN).
6. 3), 7.0-7.4 (5H, m, ArH).
7. 3), 3.6 (1H, 2t, CHN), 7.0-7.4 (5H, m, ArH).