The usefulness of combined biochemical tests in the diagnosis of Cushing's disease with negative pituitary magnetic resonance imaging

European Journal of Endocrinology

Volumn 156, Issue 2, 2007, Pages 241-248

  Testa, R M ^a   Albiger, N ^a   Occhi, G ^a   Sanguin, F ^a   Scanarini, M ^a   Berlucchi, S ^a   Gardiman, M P ^a   Carollo, C ^a   Mantero, F ^a   Scaroni, Carla ^a  

^a UNIVERSITY OF PADOVA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOTROPIN RELEASING FACTOR; CORTISONE ACETATE; DESMOPRESSIN; DEXAMETHASONE; ARGIPRESSIN[1 DEAMINO]; CORTICOTROPIN; DIAGNOSTIC AGENT; GLUCOCORTICOID; HYDROCORTISONE;

ADOLESCENT; ADRENAL HYPERPLASIA; ADRENAL INSUFFICIENCY; ADRENAL SUPPRESSION; ADULT; AGED; ARTICLE; BLOOD ANALYSIS; CLINICAL FEATURE; CONTROLLED STUDY; CUSHING DISEASE; DEXAMETHASONE SUPPRESSION TEST; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; ENDOCRINE FUNCTION TEST; FEMALE; HISTOPATHOLOGY; HORMONAL REGULATION; HORMONE SUBSTITUTION; HUMAN; HYPOPHYSIS ADENOMA; INTERMETHOD COMPARISON; MALE; NEUROSURGERY; NUCLEAR MAGNETIC RESONANCE IMAGING; POSTOPERATIVE PERIOD; PREOPERATIVE EVALUATION; PRIORITY JOURNAL; REMISSION; RETROSPECTIVE STUDY; TRANSSPHENOIDAL SURGERY; ADENOMA; BLOOD; DECISION TREE; FOLLOW UP; HYPOPHYSIS TUMOR; METABOLISM; MIDDLE AGED; PATHOLOGY; PREDICTION AND FORECASTING; PREOPERATIVE CARE; TREATMENT OUTCOME; URINE;

ADENOMA; ADOLESCENT; ADRENOCORTICOTROPIC HORMONE; ADULT; AGED; CORTICOTROPIN-RELEASING HORMONE; DEAMINO ARGININE VASOPRESSIN; DECISION TREES; DEXAMETHASONE; FEMALE; FOLLOW-UP STUDIES; GLUCOCORTICOIDS; HUMANS; HYDROCORTISONE; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; PITUITARY ACTH HYPERSECRETION; PITUITARY NEOPLASMS; PREDICTIVE VALUE OF TESTS; PREOPERATIVE CARE; REMISSION INDUCTION; RETROSPECTIVE STUDIES; TREATMENT OUTCOME;

EID: 33947712941     PISSN: 08044643     EISSN: None     Source Type: Journal    
DOI: 10.1530/eje.1.02332     Document Type: Article

References (40)

1. Invitti C, Pecori Giraldi F, De Martin M & Cavagnini F. Diagnosis and management of Cushing's syndrome: results of an Italian multicentre study. Study Group of the Italian Society of endocrinology on the pathophysiology of the hypothalamic-pituitary-adrenal axis. Journal of Clinical Endocrinology and Metabolism 1999 84 440-448.
2. Tabarin A, Laurent F, Catargi B, Olivier-Puel F, Lescene R, Berge J, Galli FS, Drouillard J, Roger P & Guerin J. Comparative evaluation of conventional and dynamic magnetic resonance imaging of the pituitary gland for the diagnosis of Cushing's disease. Clinical Endocrinology 1998 3 285-286.
3. Kaskarelis IS, Tsatalou EG, Benakis SV, Malagari K, Komninos I, Vasiliadou D, Tsagarakis S & Thalassinos N. Bilateral inferior petrosal sinuses sampling in the routine investigation of Cushing's syndrome: a comparison with MRI. American Journal of Roentgenology 2006 2 562-563.
4. Barrou Z, Abecassis JP, Guilhaume B, Thomopoulos P, Bertagna X, Derome P, Bormin A & Luton JP. Magnetic resonance imaging in Cushing disease. Prediction of surgical results. La Presse Médicale 1997 26 7-11.
5. Ludecke DK, Flitsch J, Knappe UJ & Saeger W. Cushing's disease: a surgical view. Journal of Neuro-Oncology 2001 54 151-166.
6. Coulon G, Felmann D, Arbez-Gindre F & Pageant G. Latent pituitary adenoma. Autopsy study. Semaine Des Hôpitaux 1983 59 2747-2750.
7. Diederich S & Oelkers W. A very high dose dexamethasone suppression test for differential diagnosis of Cushing's syndrome. Clinical Endocrinology 1998 48 45-51.
8. Tsagarakis S, Tsigos C, Vasiliou V, Tsiotra P, Kaskarelis J, Sotiropoulou C, Raptis SA & Thalassinos N. The desmopressin and combined CRH-Desmopressin tests in the differential diagnosis of ACTH-dependent Cushing's syndrome: constraints imposed by the expression of V2 vasopressin receptors in tumors with ectopic secretion. Journal of Clinical Endocrinology and Metabolism 2002 87 1646-1653.
9. Arnaldi G, Angeli A, Atkinson AB, Bertagna X, Cavagnini F, Chrousos GP, Fava GA, Findling JW, Gaillard RC, Grossman AB, Kola B, Lacroix A, Mancini T, Mantero F, Newell-Price J, Nieman LK, Sonino N, Vance ML, Giustina A & Boscaro M. Diagnosis and complications of Cushing's syndrome: a consensus statement. Journal of Clinical Endocrinology and Metabolism 2003 88 5593-5602.
10. Swearingen B, Katznelson L, Miller K, Grinspoon S, Waltman A, Dorer DJ, Klibanski A & Biller BM. Diagnostic errors after inferior petrosal sinus sampling. Journal of Clinical Endocrinology and Metabolism 2004 89 3752-3763.
11. Oldfield EH, Doppman JL, Nieman LK, Chrousos GP, Miller DL, Katz DA, Cutler GB Jr & Loriaux DL. Petrosal sinus sampling with and without corticotrophin-releasing hormone for the differential diagnosis of Cushing's syndrome. New England Journal of Medicine 1991 26 897-905.
12. Colao A, Faggiano A, Pivonello R, Pecori Giraldi F, Cavagnini F & Lombardi G. Study Group of the Italian Endocrinology Society on the Pathophysiology of the hypothalamic-pituitary-adrenal axis. Inferior petrosal sinus sampling in the differential diagnosis of Cushing's syndrome: results of an Italian multicenter study. European Journal of Endocrinology 2001 144 499-507.
13. Bonelli FS, Huston J, III, Carpenter PC, Erickson D, Young WF Jr & Meyer FB. Adrenocorticotropic hormone-dependent Cushing's syndrome: sensitivity and specificity of inferior petrosal sinus sampling. American Journal of Neuroradiology 2000 21 690-696.
14. Findling JW & Raff H. Screening and diagnosis of Cushing's syndrome. Endocrinology and Metabolism Clinics of North America 2005 34 385-402.
15. Tabarin A, Laurent F, Catargi B, Oliver-Puel F, Lescene R, Berge J, Galli FS, Drouillard J, Roger P & Guerin J. Comparative evaluation of conventional and dynamic magnetic resonance imaging of the pituitary gland for the diagnosis of Cushing's disease. Clinical Endocrinology 1998 49 293-300.
16. Reimondo G, Paccotti P, Minetto M, Termine A, Sturat G, Bergui M, Angeli A & Terzolo M. The corticotrophin-releasing hormone test is the most reliable noninvasive method to differentiate pituitary from ectopic secretion in Cushing's syndrome. Clinical Endocrinology 2003 58 718-724.
17. Terzolo M, Reimondo G, Ali A, Borretta G, Cesario F, Pia A, Paccotti P & Angeli A. The limited value of the desmopressin test in the diagnostic approach to Cushing syndrome. Clinical Endocrinology 2001 54 609-616.
18. Newell-Price J, Morris DG, Drake WM, Korbonits M, Monson JP, Besser GM & Grossman AB. Optimal response criteria for the human CRH test in the differential diagnosis of ACTH-dependent Cushing's syndrome. Journal of Clinical Endocrinology and Metabolism 2002 87 1640-1645.
19. Pecori Giraldi F, Invitti C, Cavagnini F & the Study Group of the Italian Society of Endocrinology on the Pathophysiology of the hypothalamic-pituitary-adrenal axis. The corticotropin-releasing hormone test in the diagnosis of ACTR-dependent Cushing's syndrome: a reappraisal. Clinical Endocrinology 2001 54 601-607.
20. Tsagarakis S, Vasiliou V, Kokkoris P, Stavropoulos G & Thalassinos N. Comparison of cortisol and ACTH responses to the desmopressin test between patients with Cushing's syndrome and simple obesity. Clinical Endocrinology 1999 51 473-477.
21. Moro M, Putignano P, Losa M, Invitti C, Maraschini C & Cavagnini F. The desmopressin test in the differential diagnosis between Cushing's disease and pseudo-Cushing states. Journal of Clinical Endocrinology and Metabolism 2000 85 3569-3573.
22. Scott LV, Medbak S & Dinan T. ACTH and cortisol release following intravenous desmopressin: a dose-response study. Clinical Endocrinology 1999 51 653-658.
23. Arlt W, Dahia PLM, Callies F, Nordmeyer JP, Allolio B, Grossman AB & Reincke M. Ectopic ACTH production by a bronchial carcinoid tumour responsive to desmopressin in vivo and in vitro. Clinical Endocrinology 1997 47 623-627.
24. Tyrrell JB, Findling JW, Aron DC, Fitzgerald PA & Forsham PH. An overnight high-dose dexamethasone suppression test for rapid differential diagnosis of Cushing's syndrome. Annals of Internal Medicine 1986 104 180-186.
25. Dickstein G, Rowan De Bold C, Gaitan D, De Cherney GS, Jackson RV, Sheldon WR Jr, Nicholson WE & Orth D. Plasma corticotropin and cortisol responses to ovine corticotropin-releasing hormone (CRH), arginine vasopressin (AVP), CRH plus AVP, and CRH plus metyrapone in patients with Cushing's disease. Journal of Clinical Endocrinology and Metabolism 1996 81 2934-2941.
26. Dichek HL, Nieman LK, Oldfield EH, Pass HI, Malley JD & Cutler GB Jr. A comparison of the standard high dose dexamethasone suppression test and the overnight 8-mg dexamethasone suppression test for the differential diagnosis of adrenocorticotropin-dependent Cushing's syndrome. Journal of Clinical Endocrinology and Metabolism 1994 78 418-422.
27. Isidori AM, Kaltsas GA, Mohammed S, Morris DG, Jenkins P, Chew SL, Monson JP, Besser GM & Grossman AB. Discriminatory value of the low-dose dexamethasone suppression test in establishing the diagnosis and differential diagnosis of Cushing's syndrome. Journal of Clinical Endocrinology and Metabolism 2003 88 5299-5306.
28. Hermus AR, Pieters GF, Pesman GJ, Smals AG, Benraad TJ & Kloppenborg PW. The corticotropin-releasing-hormone test versus the high-dose dexamethasone test in the differential diagnosis of Cushing's syndrome. Lancet 1986 2 540-544.
29. Newell-Price J, Perry L, Medbak S, Monson J, Savage M, Besser M & Grossman A. A combined test using desmopressin and corticotropin-releasing hormone in the differential diagnosis of Cushing's syndrome. Journal of Clinical Endocrinology and Metabolism 1997 82 176-181.
30. Bochicchio D, Losa M & Buchfelder M. Factors influencing the immediate and late outcome of Cushing's disease treated by transsphenoidal surgery: a retrospective study by the European Cushing's Disease Survey Group. Journal of Clinical Endocrinology and Metabolism 1995 80 3114-3120.
31. Salenave S, Gatta B, Pecheur S, San-Galli F, Visot A, Lasjaunias P, Roger P, Berge J, Young J, Tabarin A & Chanson P. Pituitary magnetic resonance imaging findings do not influence surgical outcome in adrenocorticotropin-secreting microadenomas. Journal of Clinical Endocrinology and Metabolism 2004 89 3371-3376.
32. Blevins LS Jr, Clark RV & Owens DS. Thromboembolic complications after inferior petrosal sinus sampling in patients with Cushing's syndrome. Endocrine Practice 1998 4 365-367.
33. Diez JJ & Iglesias P. Pulmonary thromboembolism after inferior petrosal sinus sampling in Cushing's syndrome. Clinical Endocrinology 1997 46 7 77.
34. Newell-Price J, Bertagna X, Grossman AB & Nieman LK. Cushing's syndrome. Lancet 2006 367 1605-1617.
35. Esposito F, Dusick JR, Cohan P, Moftakhar P, McArthur D, Wang C, Swerdloff RS & Kelly DF. Clinical review: early morning cortisol levels as a predictor of remission after transsphenoidal surgery for Cushing's disease. Journal of Clinical Endocrinology and Metabolism 2006 9 7-13.
36. Burke CW, Adams CB, Esiri MM, Morris C & Bevan JS. Transsphenoidal surgery for Cushing's disease: does what is removed determine the endocrine outcome? Clinical Endocrinology 1990 33 525-537.
37. Hammer GD, Tyrrel BJ, Lamborn KR, Applebury CB, Hannegan ET, Bell S, Rahl R, Lu A & Wilson CB. Transsphenoidal microsurgery for Cushing's disease: initial outcome and long-term results. Journal of Clinical Endocrinology and Metabolism 2004 89 6348-6357.
38. Simpson DJ, McNicol AM, Murray DC, Bahar A, Turner HE, Wass JA, Esiri MM, Clayton RN & Farrell WE. Thromboembolic complications after inferior petrosal sinus sampling in patients with Cushing's syndrome. Clinical Cancer Research 2004 5 1780-1788.
39. Kovacs K, Horvath E, Coire C, Cusimano M, Smith H, Cheithauer BW & Lloyd RV. Pituitary corticotroph hyperplasia preceding adenoma in a patient with Nelson's syndrome. Clinical Neuropathology 2006 2 74-80.
40. Salgado LR, Mendonca BB, Goldman J, Semer M, Knoepfelmacher M, Tsanaclis AM, Wajchenberg BL & Liberman B. Failure of partial hypophysectomy as definitive treatment in Cushing's disease owing to nodular corticotrope hyperplasia: report of four cases. Endocrine Pathology 1995 6 57-66.